Significance of IgM anti-HCVcore level in chronic hepatitis C

Journal of Hepatology

Volumn 27, Issue 1, 1997, Pages 36-41

  Papatheodoridis, George V ^a   Delladetsima, Johanna K ^b   Katsoulidou, Antigoni ^c   Sypsa, Vana ^c   Albrecht, Monika ^d   Michel, Gerd ^d   Hatzakis, Angelos ^c   Tassopoulos, Nicolaos C ^a  

^a Western Attica General Hospital   (Greece)

^b UNIVERSITY OF ATHENS   (Greece)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^d ABBOTT GMBH AND CO KG   (Germany)

Author keywords

Chronic hepatitis C; HCV genotype; IgM anti HCVcore; Serum HCV RNA

Indexed keywords

ALANINE AMINOTRANSFERASE; CORE PROTEIN; DNA; HEPATITIS C ANTIBODY; HEPATITIS C ANTIGEN; IMMUNOGLOBULIN M ANTIBODY; VIRUS RNA;

ADULT; AGE; AGED; ARTICLE; CONTROLLED STUDY; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENOTYPE; HEPATITIS C; HUMAN; HYBRIDIZATION; LIVER BIOPSY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0030797450     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(97)80277-2     Document Type: Article

References (26)

1. Kuo G, Choo Q-L, Alter HJ, Gitnick GL, Redeker AG, Purcell RH, et al. An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Science. 244:1989;362-364.
2. Van der Poel CJ, Cuypers HTM, Reesnick HW, Weiner AJ, Quan S, di Nello R, et al. Confirmation of hepatitis C virus infection by new four-antigen recombinant immunoblot assay. Lancet. 337:1991;317-319.
3. Yuki N, Hayashi N, Hagiwara H, Takehara T, Oshita M, Kasahara A, et al. Serodiagnosis of chronic hepatitis C in Japan by second generation recombinant immunoblot assay. J Hepatol. 17:1993;170-174.
4. Lok ASF, Cheung R, Chan R, Liu V. Hepatitis C viremia in patients with hepatitis C virus infection. Hepatology. 15:1992;1007-1012.
5. Quiroga JA, Campillio ML, Catillo I, Bartolome J, Porres JC, Carreno V. IgM antibody to hepatitis C virus in acute and chronic hepatitis C. Hepatology. 14:1991;38-43.
6. Chau KH, Dawson GJ, Mushahwar IK, Gutierrez RA, Johnson RG, Lesniewski RR, et al. IgM-antibody response to hepatitis C virus antigens in acute and chronic post-transfusion non-A, non-B hepatitis. J Virol Meth. 35:1991;343-352.
7. Clemens JM, Taskar S, Chau K, Vallari D, Shih JW-K, Alter HJ, et al. IgM antibody response in acute hepatitis C viral infection. Blood. 79:1992;169-172.
8. Brillanti S, Masci C, Ricci P, Miglioli M, Barbara L. Significance of Igm antibody to hepatitis C virus in patients with chronic hepatitis C. Hepatoloy. 15:1992;998-1001.
9. Chen P-J, Wang J-T, Hwang L-H, Yang Y-H, Hsieh C-L, Kao J-H, et al. Transient immunoglobulin M antibody response to hepatitis C virus capsid antigen in postransfusion hepatitis C: putative serological marker for acute viral infection. Proc Natl Acad Sci USA. 89:1992;5971-5975.
10. Tassopoulos NC, Hatzakis AE, Papatheodoridis GV, Karvountzis G, Troonen H, Lennartz L. Early prediction of successful alpha-interferon therapy of chronic hepatitis C by core-IgM antibodies to hepatitis C virus. J Hepatol. 20:1994;305-306.
11. Yuki N, Hayashi N, Ohkawa K, Hagiwara H, Oshita M, Katayama K, et al. The significance of immunoglobulin M antibody response to hepatitis C virus core protein in patients with chronic hepatitis C. Hepatology. 22:1995;402-406.
12. Quiroga JA, Van Binsbergen J, Wang JV, Pardo M, Navas S, Trines C, et al. Immunoglobulin M antibody to hepatitis C core antigen: correlations with viral replication, histological activity, and liver disease outcome. Hepatology. 22:1995;1635-1640.
13. Shindo M, Di Bisceglie AM, Cheung L, Shih W-K, Cristiano K, Feinstone SM, et al. Decrease in serum hepatitis C viral RNA during alpha-interferon therapy for chronic hepatitis C. Ann Intern Med. 115:1991;700-704.
14. Lau JYN, Davis GL, Kniffen J, Qian K-P, Urdea MS, Chan CS, et al. Significance of serum hepatitis C virus RNA levels in chronic hepatitis C. Lancet. 341:1993;1501-1504.
15. Tsubota A, Chayama K, Ikeda K, Yasuzi A, Koida I, Saitoh S, et al. Factors predictive of response to interferon-α therapy in hepatitis C virus infection. Hepatology. 19:1994;1088-1094.
16. Young KKY, Resnick RM, Myers TW. Detection of hepatitis C virus by a combined reverse transcription-polymerase chain reaction assay. J Clin Microb. 31:1993;882-886.
17. Stuyver L, Rossau R, Wyseur A, Duhamel M, Vanderborght B, Van Heuverswyn H, et al. Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay. J Gen Virol. 74:1993;1093-1102.
18. Simmonds P, Smith DB, McOmish F, Yap PL, Kolberg J, Urdea MS, et al. Identification of genotypes of hepatitis C virus by sequence comparisons in the core, E1 and NS-5 regions. J Gen Virol. 75:1994;1053-1061.
19. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ. Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology. 19:1994;1513-1520.
20. Hellstrom UB, Sylvan SPE, Decker RH, Sonnerborg A. Immunoglobulin M reactivity towards the immunologically active region sp75 of the core protein of hepatitis C virus (HCV) in chronic HCV infection. J Med Virol. 39:1993;325-332.
21. Nagayama R, Miyake K, Tsuda F, Okamoto H. IgM antibody to a hepatitis C virus core peptide (CP14) for monitoring activity of liver disease in patients with acute or chronic hepatitis C. J Med Virol. 42:1994;311-317.
22. Pawlotsky J-M, Darthuy F, Remire J, Pellet C, Udin L, Stuyver L, et al. Significance of anti-hepatitis C virus cone IgM antibodies in patients with chronic hepatitis C. J Med Virol. 47:1995;285-291.
23. Kato N, Sekiya H, Ootsuyama Y, Nakazawa T, Hijikata M, Ohkoshi S, et al. Humoral immune response to hypervariable region 1 of the putative envelope glycoprotein (gp70) of hepatitis C virus. J Virol. 67:1993;3923-3930.
24. Martinelli ALC, Brown D, Braun H-B, Michel G, Dusheiko GM. Quantitative assessment of hepatitis C virus RNA and IgM antibodies to hepatitis C core in chronic hepatitis C. J Hepatol. 24:1996;21-26.
25. Negro F, Abate ML, Mondardini A, Baldi M, Leandro G, Lombardi S, et al. The fluctuations of hepatitis C virus RNA and IgM anti-HCV (core) serum levels correlate with those of alanine aminotransferase during the hepatitis relapses of patients treated with interferon. J Viral Hepatitis. 2:1995;171-174.
26. Sjogren MH, Hoofnagle JH, Waggoner JG. Effect of corticosteroid therapy on levels of antibody to hepatitis B core antigen in patients and chronic type B hepatitis. Hepatology. 7:1987;582-585.