Endurance exercise modulates neuromuscular junction of C57BL/6NNia aging mice

Journal of Applied Physiology

Volumn 83, Issue 1, 1997, Pages 59-66

  Fahim, Mohamed A ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

Author keywords

Morphology; Physiology; Safety margin; Synaptic plasticity; Transmitter release

Indexed keywords

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAPACITANCE BLOOD VESSEL; CONTROLLED STUDY; ENDPLATE POTENTIAL; ENDURANCE; EXERCISE; GLUTEUS MAXIMUS MUSCLE; HISTOPATHOLOGY; MALE; MEMBRANE STEADY POTENTIAL; MOUSE; NERVE ENDING; NEUROMODULATION; NEUROMUSCULAR JUNCTION DISORDER; NONHUMAN; PRIORITY JOURNAL;

EID: 0030797413     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1997.83.1.59     Document Type: Article

References (30)

1. Alshuaib, W. B., and M. A. Fahim. Aging increases calcium influx at motor nerve terminal. Int. J. Dev. Neurosci. 8: 655-666, 1990.
2. Andonian, M. H., and M. A. Fahim. Effects of endurance exercise on the morphology of mouse neuromuscular junctions during aging. J. Neurocytol. 16: 589-599, 1987.
3. Banker, B. Q., S. S. Kelly, and N. Robbins. Neuromuscular transmission and correlative morphology in young and old mice. J. Physiol. (Lond.) 339: 355-375, 1983.
4. Cardasis, C. A., and D. M. LaFontaine. Aging rat neuromuscular junctions; a morphometric study of cholinesterase-stained whole mounts and ultrastructure. Muscle Nerve 10: 200-213, 1987.
5. Dorlochter, M., A. Irintchev, M. Brinkers, and A. Wernig. Effects of enhanced activity on synaptic transmission in mouse extensor digitorum longus muscle. J. Physiol. (Lond.) 436: 283-292, 1991.
6. Fahim, M. A. Chronic corticosterone treatment-induced ultrastructural changes at rat neuromuscular junction. Anat. Rec. 242: 424-431, 1995.
7. Fahim, M. A. Morphological correlates of physiological responses in partially denervated mouse muscle during aging. Int. J. Dev. Neurosci. 11: 303-310, 1993.
8. Fahim, M. A. Rapid neuromuscular remodelling following limb immobilization. Anat. Rec. 24: 102-109, 1989.
9. Fahim, M. A., J. A. Holley, and N. Robbins. Scanning and light microscopic study of age changes at a neuromuscular junction in the mouse. J. Neurocytol. 12: 13-25, 1983.
10. Fahim, M. A., and N. Robbins. Ultrastructural studies of young and old mouse neuromuscular junction. J. Neurocytol. 11: 641-656, 1982.
11. Fahim, M. A., N. Robbins, and R. Price. Fixation effects on synaptic vesicle density in neuromuscular junctions of young and old mice. Neurobiol. Aging 8: 71-75, 1987.
12. Herrera, A. A., A. D. Grinnell, and B. Wolowske. Ultrastructural correlates of naturally-occurring differences in transmitter release efficacy in frog motor nerve terminals. J. Neurocytol. 14: 193-202, 1985.
13. Herscovich, S., and D. Gershon. Effects of aging and physical training on the neuromuscular junction of the mouse. Gerontology 33: 7-13, 1987.
14. Howald, H., H. Hoppeler, H. Classen, O. Mathieu, and R. Straub. Influences of endurance training on the ultrastructural composition of the different muscle fiber types in humans. Pflügers Arch. 403: 369-376, 1985.
15. Irintchev, A., and A. Wernig. Muscle damage and repair in voluntary running mice; strain and muscle differences. Cell Tissue Res. 249: 509-521, 1987.
16. Ko, C. P., and L. Chen. Synaptic remodelling revealed by repeated in vivo observations and electron microscopy of identified frog neuromuscular junctions. J. Neurocytol. 16: 1780-1790, 1996.
17. Kovanen, V., and H. Suominen. Effects of age and life-time physical training on fiber composition of slow and fast skeletal muscle in rats. Pflügers Arch. 408: 543-551, 1987.
18. Larsson, L., and T. Ansved. Effects of ageing on the motor unit. Prog. Neurobiol. 45: 397-458, 1995.
19. Lichtman, J. W. A., L. Magrassi, andD. Purves. Visualisation of neuromuscular junctions over periods of several months in living mice. J. Neurosci. 7: 1215-1222, 1987.
20. Lomo, T., and O. Waerhaug. Motor endplates in fast and slow muscles of rat; what determines their differences? J. Physiol. (Paris) 80: 290-297, 1985.
21. Lynch, G. S., B. J. Rodgers, and D. A. Williams. The effects of age and low-intensity endurance exercise on the contractile properties of single skinned fast- and slow-twitch skeletal muscle fibers. Growth, Dev. Aging 57: 147-161, 1993.
22. Pierotti, D. J., R. R. Roy, R. J. Gregor, and V. R. Edgerton. Electromyographic activity of cat hindlimb flexors and extensors during locomotion at varying speeds and inclines. Brain Res. 481: 57-66, 1989.
23. Robbins, N., and M. A. Fahim. Progression of changes in mature mouse motor nerve terminals and its relation to locomotor activity. J. Neurosci. 14: 1019-1036, 1985.
24. Silbermann, M., S. Finkelbrand, A. Weiss, D. Gershon, and A. Reznick. Morphometric analysis of aging skeletal muscle following endurance training. Muscle Nerve 6: 136-142, 1983.
25. Smith, D. O., and M. R. Chapman. Acetylcholine receptor binding properties at the rat neuromuscular junction during aging. J. Neurochem. 48: 1834-1841, 1987.
26. Smith, D. O., and M. H. Weiler. Acetylcholine metabolism and choline availability at the neuromuscular junction of mature adult and aged rats. J. Physiol. (Lond.) 383: 693-709, 1987.
27. Stoop, R., and M. M. Poo. Synaptic modulation by neurotrophic factors: differential and synergistic effects of brain-derived neurotrophic factor and ciliary neurotrophic factor. J. Neurosci. 16: 3256-3264, 1996.
28. Swanson, G. J., and G. Vrbova. Effects of low calcium and inhibition of calcium-activated neutral protease (CANP) on mature nerve terminal structure in the rat sternocostalis muscle. Brain Res. 430: 199-203, 1987.
29. Washio, H., C. Imazato-Tanaka, K. Kanda, and S. Nomoto. Choline acetyltransferase and acetylcholinesterase activities in muscles of aged mice. Brain Res. 416: 69-74, 1987.
30. Wernig, A., A. Irintchev, and P. Weisshaupt. Muscle injury, cross-sectional area, and fiber type distribution in mouse soleus after intermittent wheel-running. J. Physiol. (Lond.) 428: 639-652, 1990.