Idiopathic thrombocytopenic purpura in a liver transplant recipient with previous primary biliary cirrhosis

Journal of Clinical Gastroenterology

Volumn 24, Issue 4, 1997, Pages 274-275

  Yoshida, Eric M ^a,b,e   Mandl, Lisa A ^a   Erb, Siegfried R ^a   Buckley, Alan B ^c   Scudamore, Charles H ^b   Buskard, Noel A ^d  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c British Columbia Transplant Society ^*  (Canada)

^d ROYAL JUBILEE HOSPITAL   (Canada)

^e British Columbia Transplant Society   (Canada)

Author keywords

Idiopathic thrombocytopenic purpura; Immune; Liver; Primary biliary cirrhosis; Thrombocytopenia; Transplantation

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN A; IMMUNOSUPPRESSIVE AGENT; PHENOBARBITAL; PREDNISONE; RANITIDINE;

ADULT; ARTICLE; CASE REPORT; DISEASE ASSOCIATION; FEMALE; GRAFT REJECTION; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; IMMUNOLOGICAL TOLERANCE; IMMUNOSUPPRESSIVE TREATMENT; LIVER TRANSPLANTATION; POSTOPERATIVE COMPLICATION; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL;

ADULT; FEMALE; HUMANS; IMMUNOSUPPRESSION; LIVER CIRRHOSIS, BILIARY; LIVER TRANSPLANTATION; POSTOPERATIVE COMPLICATIONS; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; TIME FACTORS;

EID: 0030797356     PISSN: 01920790     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004836-199706000-00022     Document Type: Article

References (17)

1. Kaplan MM. Primary biliary cirrhosis. N Engl J Med 1987;316: 521-8.
2. George JN, El-Harake MA, Raskob GE. Chronic idiopathic thrombocytopenic purpura. N Engl J Med 1994;331:1207-11.
3. Chazot C, Vital Durand D, Sibille M, Levrat R. Primary biliary cirrhosis and idiopathic thrombocytopenic purpura: a new association. Rev Med Interne 1983;4:173-235.
4. Selinger S, Tsai J, Pulini M, et al. Autoimmune thrombocytopenia and primary biliary cirrhosis with hypoglycemia and insulin receptor auto-antibodies. Ann Intern Med 1987;107:686-8.
5. Chalmers EA, Chan Lam D, Holder RJ, Fitzimons EJ. Familial primary biliary cirrhosis and autoimmune thrombocytopenia. Scott Med J 1987;32:152.
6. Kumazawa K, Kayanuma K, Kamiya T, et al. A case of granulomatous polymyositis associated with primary biliary cirrhosis and immune thrombocytopenic purpura. Rinsho Shinkeigaku 1987;27:867-72.
7. Wallerstedt S, Westin J, Hansson G. Primary biliary cirrhosis presenting as idiopathic thrombocytopenic purpura with deterioration after splenectomy. Ann Intern Med 1990;228:411.
8. Panzer S, Penner E, Nelson PJ, et al. Identification of the platelet glycoprotein IIb/IIIa complex as a target antigen in primary biliary cirrhosis-associated autoimmune thrombocytopenia: evidence that platelet reactive autoantibodies can also bind to the mitochondrial antigen M2. J Autoimmun 1990;3:473-83.
9. Semple JW, Freedman J. Cellular immune mechanisms in chronic autoimmune thrombocytopenic purpura (ATP). Autoimmunity 1992;13:311-9.
10. Bassendine MF, Collins JD, Stephenson J, et al. Platelet associated immunoglobulins in primary biliary cirrhosis: a cause of thrombocytopenia? Gut 1985;26:1074-9.
11. Suou R, Civeira MP, Kanof ME, et al. Defective immunoregulation in primary biliary cirrhosis: CD4+, Leu-8+ T cells have abnormal activation and suppressor function in vitro. Hepatology 1989;10:408-13.
12. Gershwin ME, Mackay IR. Primary biliary cirrhosis: paradigm or paradox for autoimmunity? Gastroenterology 1991;100:822-33.
13. Quiquandon I, Feraux P, Cavlier MT, et al. Re-evaluation of the role of azathioprine in the treatment of adult chronic idiopathic thrombocytopenic purpura: a report on 53 cases. Br J Haematol 1990;74:223-8.
14. Schiavotto C, Castaman G, Rodeghiero F. Treatment of idiopathic thrombocytopenic purpura with refractoriness to or with contraindication for corticosteroids and/or splenectomy with immunosuppression therapy and danazol. Haematologica 1993;78(Suppl. 2):29-34.
15. Kelsey PR, Schofield KP, Geary CG. Refractory idiopathic thrombocytopenic purpura (ITP) treated with cyclosporine. Br J Haematol 1985;60:197-203.
16. Matsumura O, Kawashima Y, Kato S, et al. Therapeutic effect of cyclosporine in thrombocytopenia associated with autoimmune disease. Transplant Proc 1988;20(Suppl. 4):317-22.
17. Randoux O, Gambiez L, Navarro F, et al. Post-liver transplantation thrombocytopenia: a persistent immunologic sequestration? Transplant Proc 1995;27:1710-1.