Alternative insulin delivery systems: How demanding should the patient be?

Diabetologia

Volumn 40, Issue SUPPL. 2, 1997, Pages

  Polonsky, K S ^a,b   Byrne, M M ^a   Sturis, J ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN;

CONFERENCE PAPER; DIABETES MELLITUS; DRUG DELIVERY SYSTEM; HUMAN; INSULIN RELEASE; INSULIN TREATMENT; PATIENT SATISFACTION; PRIORITY JOURNAL;

BLOOD GLUCOSE; CONSUMER SATISFACTION; DIABETES MELLITUS, TYPE 1; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN INFUSION SYSTEMS;

EID: 0030796922     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051417     Document Type: Conference Paper

References (20)

1. Polonsky KS, Licinio-Paixao J, Given BD et al. (1986) Use of biosynthetic human C-peptide in the measurement of insulin secretion rates in normal volunteers and type I diabetic patients. J Clin Invest 77: 98-105
2. Polonsky KS, Given BD, Van Cauter E (1988) Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects. J Clin Invest 81: 442-448
3. Polonsky KS, Given BD, Hirsch L et al. (1988) Quantitative study of insulin secretion and clearance in normal and obese subjects. J Clin Invest 81: 435-441
4. Sturis J, Van Cauter E, Blackman JD, Polonsky KS (1991) Entrainment of pulsatile insulin secretion by oscillatory glucose infusion. J Clin Invest 87: 439-445
5. Byrne MM, Sturis J, Polonsky KS (1995) Insulin secretion and clearance during low-dose graded glucose infusion. Am J Physiol 268: E21-E27
6. Bergman RN, Phillips LS. Cobelli C (1981) Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose. J Clin Invest 68: 1456-1467
7. Lang DA, Matthews DR, Burnett M, Turner RC (1981) Brief, irregular oscillations of basal plasma insulin and glucose concentrations in diabetic man. Diabetes 30: 435-439
8. Polonsky KS, Given BD, Hirsch LJ et al. (1988) Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus. N Engl J Med 318: 1231-1239
9. O'Meara NM, Sturis J, Van Cauter E, Polonsky KS (1993) Lack of control by glucose of ultradian insulin secretory oscillations in impaired glucose tolerance and in non-insulin dependent diabetes mellitus. J Clin Invest 92: 262-271
10. O'Rahilly S, Turner RC, Matthews DR (1988) Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes. N Engl J Med 318: 1225-1230
11. Byrne M, Sturis J, Polonsky K (1995) Insulin secretory defects in prediabetes. Diabetes 44 [Suppl 1]: 195A (Abstract)
12. Prager R, Wallace P, Olefsky JM (1986) In vivo kinetics of insulin action on peripheral glucose disposal and hepatic glucose output in normal and obese subjects. J Clin Invest 78: 472-481
13. Yang YJ, Hope ID, Bergman RN (1989) Insulin transport across capillaries is rate limiting for insulin action in dogs. J Clin Invest 84: 1620-1628
14. Sturis J, Polonsky KS, Mosekilde E, Van Cauter E (1991) Computer model for mechanisms underlying ultradian oscillations of insulin and glucose. Am J Physiol 260: E801-E809
15. Mirouze J, Selam JL, Pham TC, Cavadore D (1977) Evaluation of exogenous insulin homeostasis by the artificial pancreas in insulin-dependent diabetes. Diabetologia 13: 273-278
16. Byrne MM, Sturis J, Clément K et al. (1994) Insulin secretory abnormalities in subjects with hyperglycemia due to glucokinase mutations. J Clin Invest 93: 1120-1130
17. Nishida K, Sakakida M, Ichinose I et al. (1995) Development of a ferrocene-mediated needle-type glucose sensor covered with newly designed biocompatible membrane, 2-methacryloyloxyethyl phosphorylcholine -co-n-butyl methacrylate. Diabetes 44 [Suppl 1]: 127A (Abstract)
18. Blackman JD, Polonsky KS, Jaspan JB, Sturis J, Van Cauter E, Thistlethwaite JR (1992) Insulin secretory profiles and C-peptide clearance kinetics at 6 months and 2 years after kidney-pancreas transplantation. Diabetes 41: 1346-1354
19. Duckworth WC, Saudek CD, Henry RR (1992) Why intraperitoneal delivery of insulin with implantable pumps in NIDDM? Diabetes 41: 657-661
20. Sturis J, Scheen AJ, Leproult R, Polonsky KS, Van Cauter E (1995) 24-hour glucose profiles during continuous or oscillatory insulin infusion: demonstration of the functional significance of ultradian insulin oscillations. J Clin Invest 95:1464-1471