Upregulation of phagocytosis and candidicidal activity of macrophages exposed to the immunostimulant, acemannan

International Journal of Immunopharmacology

Volumn 19, Issue 2, 1997, Pages 75-82

  Stuart, R W ^a   Lefkowitz, D L ^a   Lincoln, J A ^a   Howard, K ^a   Gelderman, M P ^a   Lefkowitz, S S ^b  

^a TEXAS TECH UNIVERSITY   (United States)

^b TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Acemannan; Candida albicans; Chemiluminescence; Macrophage activity; Phagocytosis

Indexed keywords

ACEMANNAN; IMMUNOSTIMULATING AGENT;

ANIMAL CELL; ARTICLE; CANDIDA ALBICANS; COCULTURE; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; FEMALE; FLUORESCENCE MICROSCOPY; IN VITRO STUDY; INTRACELLULAR KILLING; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PRIORITY JOURNAL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CANDIDA ALBICANS; CATTLE; FEMALE; MACROPHAGE ACTIVATION; MACROPHAGES, PERITONEAL; MALE; MANNANS; MANNOSE; MICE; MICE, INBRED C57BL; PHAGOCYTOSIS; RESPIRATORY BURST; SERUM ALBUMIN; UP-REGULATION;

EID: 0030796908     PISSN: 01920561     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0192-0561(97)00010-6     Document Type: Article

References (21)

1. Adams, D. O. (1992). Macrophage activation. In Encyclopedia of Immunology (eds Roitt, I. & Delves, P.), pp. 1020-1026. W.B. Saunders Co. Philadelphia, PA.
2. Domer, J. E. & Lehrer, R. I. (1993). Introduction to candida: systemic candidiasis. In Fungal Infections and Immune Respiratory (ed. Jueann Murphy, W.) pp. 49-71. Plenum Press, New York.
3. Gelderman, M. P., Lefkowitz, D. L., Lefkowitz, S. S., Bollen A. & Moguilevsky N. Exposure of macrophages to an enzymatically inactive macrophage mannose receptor ligand augments killing of Candida albicans (submitted).
4. Greenberg, S. & Silverstein, S. C. (1993). Phagocytosis. In: Fundamental Immunology (ed. Paul, W.), pp. 941-964. Raven Press, New York.
5. Hirai, K. I., Moriguchi, K. & Wang, G. Y. (1991) Human neutrophils produce free radicals from the cell-zymosan interface during phagocytosis and from the whole plasma membrane when stimulated with calcium ionophore A23187. Exp. cell. Res., 194, 19-27.
6. Hostetter, M. K. (1994) Interactions of Candida albicans with eukaryotic cells. ASM News, 60, 370-374.
7. Kullberg, B. J., Van't-Wont, J. W., Hoogstraten, C. & Van Furth, R. (1993) Recombinant interferon-γ enhances resistance to acute disseminated Candida albicans infection in mice. J. infect. Dis., 168, 436-443.
8. Lefkowitz, S. S., Gelderman, M. P., Lefkowitz, D. L., Moguilevsky, N. & Bollen, A. (1996) Phagocytosis and intracellular killing of Candida albicans by macrophages exposed to myeloperoxidase. J. infect. Dis., 173, 1202-1207.
9. Lefkowitz, D. L., Lefkowitz, S. S., Mone, J. & Everse, J. (1988) Peroxidase-induced enhancement of chemiluminescence by murine peritoneal macrophages. Life Sci., 43, 739-745.
10. Lefkowitz, D. L., Lefkowitz, S. S., Wei, R. Q. & Everse, J. (1986). Activation of macrophages with oxidative enzymes. In Methods in Enzymology, pp. 537-548. Academic Press, Orlando.
11. Lian, C. J., Hwang, W. S. & Pai, C. H. (1987) Plasmid-mediated resistance to phagocytosis in Yersinia enterocolitica. Infect. Immun., 55, 1176-1183.
12. Marshall, G. D. & Druck, J. P. (1993) In vitro stimulation of NK activity by acemannan (ACM). J. Immun., 150, 1381.
13. Marshall, G. D., Gibbons, A. S. & Parnell, L. S. (1993) Human cytokines induced by acemannan. J. Allergy Clin. Immun., 91, 295.
14. Rodriguez-Bigas, M., Cruz, N. & Suarez, A. (1988) Comparative evaluation of aloe vera in the management of burn wounds in guinea pigs. Plast. Reconstr. Surg., 81, 386-389.
15. Stahl, P. D. (1992) The macrophage mannose receptor and other macrophage lectins. Cur. Opin. Immun., 4, 49-52.
16. Susada, M. & Johnson, J. (1980) Clearance of neutrophil derived myeloperoxidase by the macrophage mannose receptor. Am. J. Respir. Cell mol. Biol., 152, 85-98.
17. Suzuki, M. T., Sherr, E. B. & Sherr, B. F. (1993) DAPI direct counting underestimates bacterial abundances and average cell size compared to AO direct counting. Limnol. Oceanogr., 38, 1566-1570.
18. Szabo, I., Guan, L. & Rogers, T. J. (1995) Modulation of macrophage phagocytic activity by cell wall components of Candida albicans. Cell Immun., 164, 182-188.
19. Taylor, M. E., Bezouska, K. & Drickamer, K. (1992) Contribution to ligand binding by multiple carbohydrate-recognition domains in the macrophage mannose receptor. J. biol. Chem., 3, 1719-1726.
20. Taylor, M. E. & Drickamer, K. (1993) Structural requirements for high affinity binding of complex ligands by the macrophage mannose receptor. J. biol. Chem., 268, 399-404.
21. Tizzard, I. & Kemp, M. (1994) Use of macrophage stimulating agents to stimulate wound healing in aged rats. Ostomy/wound Mngmt, 40, 3.