7-Spirobenzocyclohexyl derivatives of naltrexone, oxymorphone, and hydromorphone as selective opioid receptor ligands

Journal of Medicinal Chemistry

Volumn 40, Issue 19, 1997, Pages 3064-3070

  Fang, Xinqin ^a   Larson, Dennis L ^a   Portoghese, Philip S ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR ANTAGONIST; HYDROMORPHONE DERIVATIVE; MU OPIATE RECEPTOR AGONIST; NALTREXONE DERIVATIVE; OXYMORPHONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; DRUG ACTIVITY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; GUINEA PIG; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; ELECTRIC STIMULATION; GUINEA PIGS; HYDROMORPHONE; LIGANDS; MALE; MICE; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; NALTREXONE; NARCOTICS; OXYMORPHONE; RECEPTORS, OPIOID, DELTA; SPIRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030796272     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970283e     Document Type: Article

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