Prevalence of carcinoma in situ of the testis in 207 oligozoospermic men from infertile couples: Prospective study of testicular biopsies

British Medical Journal

Volumn 315, Issue 7114, 1997, Pages 989-991

  Giwercman, Aleksander ^a   Thomsen, Jørn Kvist ^b   Hertz, Jens ^b   Berthelsen, Jørgen G ^c   Jensen, Vibeke ^a   Meinecke, Birgit ^b   Thormann, Lene ^d   Storm, Hans H ^e   Skakkebæk, Niels F ^a  

^a Rigshospitalet   (Denmark)

^b GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^c HILLERØD HOSPITAL   (Denmark)

^d GLOSTRUP UNIVERSITY HOSPITAL   (Denmark)

^e DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CANCER REGISTRY; CARCINOMA IN SITU; CRYPTORCHISM; DATA ANALYSIS; DENMARK; HUMAN; HUMAN TISSUE; INFERTILITY; MAJOR CLINICAL STUDY; MALE; OLIGOSPERMIA; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK FACTOR; SPERMATOZOON DENSITY; TESTIS BIOPSY; TESTIS CARCINOMA;

EID: 0030796147     PISSN: 09598146     EISSN: None     Source Type: Journal    
DOI: 10.1136/bmj.315.7114.989     Document Type: Article

References (19)

1. Skakkebæk NE, Berthelsen JG Giwercman A Muller J. Garcinoma-in-situ of the testis possible origin from gonocytes and precursor of all typt of germ cell tunours except spermatocytoma. Int J Androl 1987;10:19-28.
2. Muller J, Skakkebæk NE, Parkinson MC. The spermatocytic seminoma: views on pathogenesis. Int J androl 1987; 10:147-56
3. Skakkebæk NE. Possible carcinoma-in-situ of the testis. Lancet 1972;ii:516-7.
4. West AB, Butler MR, Fitzpatrick J O' Brien A Testicular tumors in subfer-tile men report of 4 cases with implications for management of patients presenting with infertility J Urol 1985;133:107-9
5. Giwemnan A, von der Maase H, Skakkebæk NE. Epidemiological and clinical aspects of carcinoma in situ of the testis. Eur Urol 1993;23:104-14
6. Nüesch-Bachmann IH, Medinger C. Atypische Sperrnatogonien als Präkanzerose. Schweiz Med Wochenschr 1977; 107:795-801.
7. Pryor JP, Cameron KM, Chilton CP, Ford TF. Parkinson MC, Sinokrol J et al. Carcinoma in situ in testicular biopsies from men presenting with infertility- Br J Urol 1983;55:780-84.
8. Skakkebæk NK. Carcinoma in situ of the testise frequency and relationship to invasive germ cell tumours in infertile men. Histopathology 1978;2:157-70
9. Schutte B. Early testicular cancer in severe oligozoospermia. In: Molstein AF Leidenberger F, Hölzer KH, Bettendorf G, eds. Carl Schirren symposium achances in andrology. Berlinh: Diesbach Verlag. 1988:188-90.
10. Berthelsen JG. Skakkebæk NE. von der Maase H, Sørensen BL., Mogensen P Screening for carcinoma in situ of the Contralateral testis in patients with germinal testicular cancer. BMJ 1982;285:1683-6
11. Rowlev MJ, Meller CG. The testicular biopsy: surgical procedure, fixation, and staining technics. Fertil Steril 1966;17:177-86.
12. Bruun E. Frimodt-Moller C, Giwercman A, Lenz S, Skakkebæk NE. Testicular biopsy as an outpatientin screening carcinoma-in-situ: complications and the patients acceptance. Int J Androl 1987;10:199-202.
13. Dieckmann K-P. Loy V. Prevalence of contralateral testicular intraepithelial neoplasia in patients with lesticular germ cell neoplasms.J Clin Oncol 1996;14:3126-32
14. Giwercinan A, Kerthelsen JG, Muller J, von der Maase H, SkakkebækNK. Screning for carcinona-in-situ of the testis. Int J Androl 1987;10:173-80.
15. Dieckmann K-P. Kaup F Loy V. False-negative biopsy for testicular intraepithelial neoplasia. J Cancer Res Clin Oncol 1993;119:1-4
16. Berthelsen JG, Skakkebæk NE. Value of testicular biopsy in diagnosing carcinoma in situ testis. Scand J Urol Nephrol 1981;15:165-8.
17. Mumperow E, Lauke H. Holstein AF, Hartmanin M. Further practical experiences in the recognition and management of caninoma in situ of the testis. URol Int 1992;18:162-6.
18. Bettocchi C, Coker CB, Deacon J, Parkinson C, Pryor JP. A review of testicular intratubular germ cell neoplasia in infertile men. J. Androl 1994;14:6S.
19. Chemes HE, Casabe A, Davidzon I. Carcinoma in situ of the testis: incidence in infertility and rapid evolution to invasive seminoma. J. Androt 1995;suppl:P-24 (abstract).