Effect of adenosine analogues on the expression of matrix metalloproteinases and their inhibitors from human dermal fibroblasts

Biochemical Pharmacology

Volumn 53, Issue 10, 1997, Pages 1511-1520

  Svendsrud, Debbie Hege ^a   Loennechen, Thrina ^a   Winberg, Jan Olof ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

Author keywords

Adenosine analogues; Cell morphology; Cell viability; Matrix metalloproteinases; TIMP

Indexed keywords

3 DEAZAADENOSINE; 3 DEAZAARISTEROMYCIN; ADENOSINE DERIVATIVE; ANTIVIRUS AGENT; COLLAGENASE; GELATINASE; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; STROMELYSIN;

ARTICLE; CELL VIABILITY; COLLAGEN SYNTHESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN FIBROBLAST;

ADENOSINE; ADENOSYLHOMOCYSTEINASE; CELL SURVIVAL; CELLS, CULTURED; COLLAGENASES; DNA FRAGMENTATION; ENZYME INHIBITORS; FIBROBLASTS; GELATINASES; GLYCOPROTEINS; HUMANS; HYDROLASES; MATRIX METALLOPROTEINASE 3; METALLOENDOPEPTIDASES; PROTEASE INHIBITORS; SKIN; TISSUE INHIBITOR OF METALLOPROTEINASES; TUBERCIDIN;

EID: 0030795772     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00071-3     Document Type: Article

References (46)

1. Birkedal-Hansen H, Moore WGI, Bodden MK, Windsor LJ, Birkedal-Hansen B, DeCarlo A and Engler JA, Matrix Metalloproteinases: A review. Crit Rev Oral Biol Med 4: 197-250, 1993.
2. Matrisan LM, Metalloproteinases and their inhibitors in matrix remodeling. Trends in Genetics 6: 121-125, 1990.
3. Woessner JF Jr, Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J. 5: 2145-2154, 1991.
4. Gross J and Nagai Y, Specific degradation of the collagen molecule by tadpole collagenolytic enzyme. Proc Natl Acad Sci USA 54: 1197-1204, 1965.
5. Angel P, Baumann I, Stein B, Delius H, Rahmsdorf H and Herrlich P, 12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5′-flanking region. Mol Cell Biol 7: 2256-2266, 1987.
6. Brinckerhoff CE, Plucinska IM, Sheldon CA and O'Connor GT, Half-life of synovial cell collagenase mRNA is modulated by phorbol myristate acetate but not by all-trans-retenoic acid or dexametasone. Biochemistry 25: 6378-6384, 1986.
7. Eisen AZ, Human skin collagenase: Relationship to pathogenesis of epidermolysis dystrophica. J Invest Dermatol 52: 449-453, 1969.
8. Bauer EA, Gjedde-Dahl T Jr and Eisen AZ, The role of human skin collagenase in epidemolysis bullosa. J Invest Dermatol 68: 119-124, 1977.
9. Winberg JO, Anton-Lamprecht I, König A, Bruchner-Tuderman L, Nilssen Ø and Gjedde-Dahl T Jr, Biochemical, molecular and ultrastructural heterogeneity in severe mutilating recessive dystrophic epidermolysis bullosa. Eur J Dermatol 14: 463-470, 1994.
10. Harris ED Jr, Faulkner CS and Braun FE, Collagenolytic system in rheumatoid arthritis. Clin Orthop Relat Res 110: 303-316, 1975.
11. Stetler-Stevenson WG, Liotta L and Kleiner DE Jr, Extracellular matrix 6: Role of matrix metalloproteinase in tumor invasion and metastasis. FASEB J 7: 1434-1441, 1993.
12. MacDougall JR and Matrisian LM, Contributions of tumor and stromal matrix metalloproteinases to tumor progression, invasion and metastasis. Cancer Metastasis Rev 14: 351-362, 1995.
13. Takeda K, Hatamochi A, Arakawa M and Ueke H, Effects of tumor necrosis factor-alpha on connective tissue metabolism in normal and scleroderma fibroblast cultures. Arch Dermatol Res 284: 440-444, 1993.
14. Westermark J, Häkkinen L, Fiers W and Kähäri VM, TNF-R55-specific form of human tumor necrosis factor-α induces collagenase gene expression by human skin fibroblasts. J Invest Dermatol 105: 197-202, 1995.
15. Chirivi RGS, Garofalo A, Crimmin MJ, Bauden LJ, Stopacciaro A, Braun PD and Giavazzi R, Inhibition of the metastatic spread and growth of B16-BL6 murine melanoma by a synthetic matrix metalloproteinase inhibitor. Int J Cancer 58: 460-464, 1994.
16. Karakiulakis G, Missirlis E and Maragoudakis ME, Basement membrane collagen-degrading activity from a malignant tumor is inhibited by anthracycline antibiotics. Biochim Biophys Acta 1035: 218-222, 1990.
17. Bruckner-Tuderman L, Epidermolysis bullosa. In: Connective Tissue and its heritable disorders (Eds. Royce PM and Steinmann B), pp. 507-532. Wiley-Liss Inc, 1993.
18. Gordon D and Lewis GP, Effects of piroxicam on mononuclear cells. Inflammation (Supplement) 8: 87-102, 1984.
19. Prytz PS and Aarbakke J, Differential cell cycle perturbation by transmethylation inhibitors. Biochem Pharmacol 39: 203-206, 1990.
20. Loennechen T, Nilsen IW, Moens U, Andersen A and Aarbakke J, Is there an association between an increase in c-myc RNA steady state levels and c-myc methylation in HL-60 cells treated with 3-deaza-(±)-aristeromycin, and indirect inhibitor of methylation. Biochem Pharmacol 44: 1283-1289, 1992.
21. Prytz PS, Loennechen T, Johansson PA, Larsen LB, Slørdal L and Aarbakke J, Effects of 3-deazaadenosine, an inducer of HL-60 cell differentiation on human blood cells in vitro. Eur Paediatr Haematol Oncol 6: 173-179, 1989.
22. Montgomery JA, Clayton SJ, Thomas HJ, Shannon WM, Arnett G, Bodner AJ, Kion IK, Cantoni GL and Chiang PK, Carbocyclic analogue of 3-deazaadenosine: a novel antiviral agent using S-adenosylhomocysteine hydrolase as a pharmacological target. J Med Chem 25: 626-629, 1982.
23. De Clercq E and Montgomery JA, Broad spectrum antiviral activity of the carbocyclic analog of 3-deazaadenosine. Antiviral Res 3: 17-24, 1983.
24. Wyde PR, Ambrose MW, Meyer HL, Zolinski CL and Gilbert BE, Evaluation of the toxicity and antiviral activity of carbocyclic 3-deazaadenosine against respiratory syncytial and parainfluenza type 3 viruses in tissue culture and in cotton rats. Antiviral Res 14: 215-225, 1990.
25. Mayers DL, Mikovits JA, Joshi B, Hewlett IK, Estrada JS, Wolfe AD, Garcia GE, Doctor BP, Burke DS, Gordon RK, Lane JR and Chiang PK, Anti-human immunodeficiency virus 1 (HIV-1) activities of 3-deazaadenosine analogs: increased potency against 3′-azido-3′-deoxythymidine-resistant HIV-1 strains. Proc Natl Acad Sci USA 92: 215-219, 1995.
26. Coulombe RA Jr, Huie JM, Sharma RP and Huggins JW, Pharmacokinetics of the antiviral agent carbocyclic 3-deazaadenosine. Biochem Pharmacol 21: 555-559, 1993.
27. Schmidt JA, Bomford R, Gao XM and Rhodes J, 3-Deazaadenosine an inhibitor of interleukin 1 production by human peripheral blood monocytes. Int J Immunopharmacol 12: 89-97, 1990.
28. Jürgensen CH, Huber BE, Zimmerman TP and Wolberg G, 3-deazaadenosine inhibits leukocyte adhesion and ICAM-1 biosynthesis in tumor necrosis factor-stimulated human endothelial cells. J Immunol 144: 653-661, 1990.
29. Endresen PC, Eide TJ and Aarbakke J, Cell death initiated by 3-deazaadenosine in HL-60 cells is apoptosis and is partially inhibited by homocysteine. Biochem Pharmacol 46: 1893-1901, 1993.
30. Stopford CR, Wolberg G, Prus KL, Reynolds-Vaughn R and Zimmerman TP, 3-Deazaadenosine-induced disorganization of macrophage microfilaments. Proc Natl Acad Sci USA 82: 4060-4064, 1985.
31. Gordon S and Werb Z, Secretion of macrophage neutral proteinase is enhanced by colchicin. Proc Natl Acad Sci USA 73: 872-876, 1976.
32. Bauer EA and Valle KJ, Colchicin-induced modulation of collagenase in human skin fibroblast cultures. I. Stimulation of enzyme synthesis in normal cells. J Invest Dermatol 79: 398-402, 1982.
33. Winberg JO and Gjedde-Dahl T Jr, Epidermolysis bullosa simplex: Expression of gelatinase activity in cultured human skin fibroblasts. Biochem Genet 30: 401-420, 1992.
34. Johnson-Wint B and Hollies S, A rapid in situ deoxyribonucleic acid assay for determining cell number in culture and tissue. Anal Biochem 122: 338-344, 1982.
35. Bruckner-Tuderman L, Winberg JO, Anton-Lamprecht I, Schnyder UW and Gedde-Dahl T Jr, Anchoring fibrils, collagen VII and neutral metalloproteases in recessive dystrophic epidermolysis bullosa inversa. J Invest Dermatol 99: 550-558, 1992.
36. Heussen C and Dowdle EB, Electrophoretic analysis of plasminogen activators in polyactylamide gels containing sodium dodecyl sulfate and copolymerized substrates. Anal Biochem 102: 196-202, 1980.
37. Matzinger P, The JAM test. A simple assay for DNA fragmentation and cell death. J Immunol Methods 145: 185-199, 1991.
38. Wyllie AH, Apoptosis (the 1992 Frank Rose Memorial Letter). Br J Cancer 67: 205-208, 1993.
39. Cohen GM, Sun XM, Snowden RT, Dinsdale D and Skilleter D, Key morphological features of apoptosis in the absence of internucleosomal DNA fragmentation. Biochem J 286: 331-334, 1992.
40. Oberhammer F, Fritsch G, Pavelka M, Froshl G, Tiefenbacher R, Purchio T and Schulte-Hermann R, Induction of apoptosis in cultured hepatocytes and in the regressing liver by transforming growth factor-beta 1 occurs without activation of an endonuclease. Toxicol Lett. 64-65: 701-704, 1992.
41. Backlund PS Jr, Carotti D and Cantoni GL, Effects of the S-adenosylhomocysteine hydrolase inhibitors 3-deazaadenosine and 3-deazaaristeromycin on RNA methylation and synthesis. Eur J Biochem 160: 245-251, 1986.
42. Duerre JA, Buttz HR and Ackerman JJ, Effect of methylation inhibitors on gene expression in HL-60 cells. Biochem Cell Biol 70: 703-711, 1992.
43. Chiang PK, Burbelo PD, Brugh SA, Gordon RK, Fukuda K and Yamada Y, Activation of collagen IV gene expression in F9 teratocarcinoma cells by 3-deazaadenosine analogs. J Biol Chem 267: 3988-4991, 1992.
44. Murphy G, Cockett MI, Stephens PE, Smith BJ and Docherty AJP, Stromelysin is an activator of procollagenase. A study with natural and recombinant enzymes. Biochem J 248: 265-268, 1987.
45. Unemori EN, Bair MJ, Bauer EA and Amento EP, Stromelysin expression regulates collagenase activation in human fibroblasts. J Biol Chem 266: 23477-23482, 1991.
46. Clark IM and Cawston TE, Fragments of human fibroblast collagenase. Purification and characterization. Biochem J 263: 201-206, 1989.