Analysis of cis-acting sequence and structural elements required for antitermination of the Bacillus subtilis tyrS gene

Molecular Microbiology

Volumn 25, Issue 2, 1997, Pages 411-421

  Rollins, Sean M ^a   Grundy, Frank J ^a   Henkin, Tina M ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACILLUS SUBTILIS; BASE PAIRING; GENE SEQUENCE; GENETIC ANALYSIS; NONHUMAN; PRIORITY JOURNAL; TRANSCRIPTION TERMINATION;

BACILLUS SUBTILIS;

EID: 0030795362     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1997.4851839.x     Document Type: Article

References (26)

1. Anagnostopoulos, C., and Spizizen, J. (1961) Requirements for transformation in Bacillus subtilis. J Bacteriol 81: 741-746.
2. Dale, B.A., and Nester, E.W. (1971) Regulation of tyrosyl-transfer ribonucleic acid synthetase in Bacillus subtilis. J Bacteriol 108: 586-588.
3. Garrity, D.B., and Zahler, S.A. (1994) Mutations in the gene for a tRNA that functions as a regulator of a transcriptional attenuator in Bacillus subtilis. Genetics 137: 627-636.
4. Gendron, N., Putzer, H., and Grunberg-Manago, M. (1994) Expression of both Bacillus subtilis threonyl-tRNA synthetase genes is autogenously regulated. J Bacteriol 176: 486-494.
5. Grandoni, J.A., Zahler, S.A., and Calvo, J.M. (1992) Transcriptional regulation of the ilv-leu operon of Bacillus subtilis. J Bacteriol 174: 3212-3219.
6. Grandoni, J.A., Fulmer, S.B., Brizzio, V., Zahler, S.A., and Calvo, J.M. (1993) Regions of the Bacillus subtilis ilv-leu operon involved in regulation by leucine. J Bacteriol 175: 7581-7593.
7. Green, C.J., and Vold, B.S. (1993) tRNA, tRNA processing, and aminoacyl-tRNA synthetases. In Bacillus subtilis and other Gram-positive Bacteria: Biochemistry, Physiology, and Molecular Genetics. Sonenshein, A.L., Hoch, J.A., and Losick, R. (eds). Washington, DC: American Society for Microbiology, pp. 683-698.
8. Grundy, F.J., and Henkin, T.M. (1993) tRNA as a positive regulator of transcription antitermination in B. subtilis. Cell 74: 475-482.
9. Grundy, F.J., and Henkin, T.M. (1994) Conservation of a transcription antitermination mechanism in aminoacyl-tRNA synthetase and amino acid biosynthesis genes in Gram-positive bacteria. J Mol Biol 235: 798-804.
10. Grundy, F.J., Waters, D.A., Allen, S.H.G., and Henkin, T.M. (1993) Regulation of the Bacillus subtilis acetate kinase gene by CcpA. J Bacteriol 175: 7348-7355.
11. Grundy, F.J., Rollins, S.M., and Henkin, T.M. (1994) Interaction between the acceptor end of tRNA and the T box stimulates antitermination in the Bacillus subtilis tyrS gene: a new role for the discriminator base. J Bacteriol 176: 4518-4526.
12. Grundy, F.J., Haldeman, M.T., Hornblow, G.M., Ward, J.M., Chalker, A.F., Henkin, T.M. (1997a) The Staphylococcus aureus ileS gene, encoding isoleucyl-tRNA synthetase, is a member of the T box family. J Bacteriol 179: 3767-3772.
13. Grundy, F.J., Hodil, S.E., Rollins, S.M., and Henkin, T.M. (1997b) Specificity of tRNA-mRNA interactions in Bacillus subtilis tyrS antitermination. J Bacteriol 179: 2587-2594.
14. Henkin, T.M. (1994) tRNA-directed transcription antitermination. Mol Microbiol 13: 381-387.
15. Henkin, T.M., Glass, B.L., and Grundy, F.J. (1992) Analysis of the Bacillus subtilis tyrS gene: conservation of a regulatory sequence in multiple tRNA synthetase genes. J Bacteriol 174: 1299-1306.
16. Kunkel, T.A. (1985) Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc Natl Acad Sci USA 82: 488-492.
17. LeCuyer, K.A., and Crothers, D.M. (1994) Kinetics of an RNA conformational switch. Proc Natl Acad Sci USA 91: 3373-3377.
18. Marta, P.T., Ladner, R.D., and Grandoni, J.A. (1996) A CUC triplet confers leucine-dependent regulation of the Bacillus subtilis ilv-leu operon. J Bacteriol 178: 2150-2153.
19. Messing, J. (1983) New M13 vectors for cloning. Methods Enzymol 101: 20-78.
20. Miller, J. (1972) Experiments in Molecular Genetics. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
21. Nakano, M.M., and Zuber, P. (1989) Cloning and characterization of srfB, a regulatory gene involved in surfactin production and competence in Bacillus subtilis. J Bacteriol 171: 5347-5353.
22. Perriere, G., Goey, M., and Gojobori, T. (1994) NRSub: a non-redundant data base for the Bacillus subtilis genome. Nucleic Acids Res 22: 5525-5529.
23. Putzer, H., Gendron, N., and Grunberg-Manago, M. (1992) Coordinate expression of the two threonyl-tRNA synthetase genes in Bacillus subtilis: control by transcriptional antitermination involving a conserved regulatory sequence. EMBO J 11: 3117-3127.
24. Putzer, H., Grunberg-Manago, M., and Springer, M. (1995a) Bacterial aminoacyl-tRNA synthetases: genes and regulation of expression. In tRNA: Structure, Biosynthesis and Function. Soll, D., and RajBhandary, U. (eds). Washington, DC: American Society for Microbiology, pp. 293-333.
25. Putzer, H., Laalami, S., Brakhage, A.A., Condon, C., and Grunberg-Manago, M. (1995b) Aminoacyl-tRNA synthetase gene regulation in Bacillus subtilis: induction, repression, and growth-rate regulation. Mol Microbiol 16: 709-718.
26. Zuber, P., and Losick, R. (1987) Role of AbrB in Spo0A- and Spo0B-dependent utilization of a sporulation promoter in Bacillus subtilis. J Bacteriol 169: 2223-2230.