Effect of chronotropic and inotropic stimulation on the coronary pressure-flow relation in left ventricular hypertrophy

Basic Research in Cardiology

Volumn 92, Issue 4, 1997, Pages 271-286

  Duncker, D J ^a,b   Bache, R J ^b  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Adenosine; Aortic stenosis; Blood flow; Exercise; Supravalvular; Vasodilator reserve

Indexed keywords

ADENOSINE; DOBUTAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CHRONOTROPISM; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY PRESSURE; DOG; EXERCISE; HEART ATRIUM PACING; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE FILLING PRESSURE; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE PERFUSION; HEART RATE; INOTROPISM; MULTIVARIATE ANALYSIS; MUSCLE CONTRACTILITY; MUSCLE EXCITATION; NONHUMAN; REGRESSION ANALYSIS; SYSTOLIC BLOOD PRESSURE; VASODILATATION;

ADENOSINE; ANIMALS; BLOOD FLOW VELOCITY; BLOOD PRESSURE; CARDIOTONIC AGENTS; CORONARY VESSELS; DOBUTAMINE; DOGS; EXERTION; HEART RATE; HYPERTROPHY, LEFT VENTRICULAR; MYOCARDIAL CONTRACTION; PREDICTIVE VALUE OF TESTS; REGRESSION ANALYSIS; STIMULATION, CHEMICAL; VASODILATOR AGENTS;

EID: 0030795044     PISSN: 03008428     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00788522     Document Type: Article

References (54)

1. Alyono D, Andersen RW, Parrish DG, Dai XZ, Bache RJ (1986) Alterations of myocardial blood flow associated with experimental canine left ventricular hypertrophy secondary to valvular aortic stenosis. Circ Res 58: 47-57
2. Anderson PG, Bishop SP, Digerness SB (1988) Cardiac and vascular pathology of hydralazine treated DOCA salt rats. J Mol Cell Cardiol 20: 755-767
3. Archie JP Jr (1978) Transmural distribution of intrinsic and transmitted left ventricular diastolic intramyocardial pressure in dogs. Cardiovasc Res 12: 255-262
4. Aversano T, Klocke FJ, Mates RE, Canty JM (1984) Preload-induced alterations in capacitance-free diastolic pressure-flow relationship. Am J Physiol 246 (Heart Circ Physiol 15): H410-H417
5. Bache RJ (1988) Effects of hypertrophy on the coronary circulation. Prog Cardiovasc Disease 31: 403-440
6. Bache RJ, Alyono D, Sublett E, Dai XZ (1986) Myocardial blood flow in left ventricular hypertrophy developing in young and adult dogs. Am J Physiol 251 (Heart Circ Physiol 20): H949-H956
7. Bache RJ, Cobb FR (1977) Effect of maximal coronary vasodilation on transmural myocardial perfusion during tachycardia in the awake dog. Circ Res 41:648-653
8. Bache RJ, Dai XZ (1990) Myocardial oxygen consumption during exercise in the presence of left ventricular hypertrophy secondary to supravalvular aortic stenosis. J Am Coll Cardiol 15: 1157-1164
9. Bache RJ, Vrobel TR, Arentzen CE, Ring S (1981) Effect of maximal coronary vasodilation on transmural myocardial perfusion during tachycardia in dogs with left ventricular hypertrophy. Circ Res 49: 742-750
10. Bishop SP, Powell PC, Hasebe N, Shen YT, Patrick TA, Hittinger L, Vatner SF (1996) Coronary vascular morphology in pressure-overload left ventricular hypertrophy. J Moll Cell Cardiol 28: 141-154
11. Breisch EA, White FC, Nimmo LE, Bloor CM (1986) Cardiac vasculature and flow during pressure-overload hypertrophy. Am J Physiol 251 (Heart Circ Physiol 20): H1031-H1037
12. Brilla CG, Hanicki JD, Weber KT (1991) Impaired diastolic function and coronary reserve in genetic hypertension. Role of interstitial fibrosis and medial thickening of intramyocardial coronary arteries. Circ Res 69: 107-115
13. Canty JM, Giglia J, Kandath D (1990) Effect of tachycardia on regional function and transmural myocardial perfusion during graded coronary pressure reduction in conscious dogs. Circulation 82: 1815-1825
14. 2-adrenergic receptors in the coronary microcirculation. Circulation 84: 2108-2122
15. Chilian WM, Layne SM, Klausner C, Eastham ML (1989) Redistribution of coronary microvascular resistance produced by dipyridamole. Am J Physiol 256 (Heart Circ Physiol 25): H383-H390
16. Downey JM, Kirk ES (1975) Inhibition of coronary blood flow by a vascular waterfall mechanism. Circ Res 36: 753-760
17. Duncker DJ, Zhang J, Bache RJ (1993) Pressure-flow relation in left ventricular hypertrophy: Importance of changes in minimum resistance versus changes in back pressure. Circ Res 72: H768-H775
18. Duncker DJ, Zhang J, Pavek TJ, Crampton MJ, Bache RJ (1995) Effect of exercise on coronary pressure-flow relation in hypertrophied left ventricle. Am J Physiol 269 (Heart Circ Physiol 38): H271-H281
19. 1-adrenergic vasoconstriction. Am J Physiol 266 (Heart Circ Physiol 35): H795-H810
20. Ellis AK, Klocke FJ (1979) Effects of preload on the transmural distribution of perfusion and pressure-flow relationships in the canine coronary vascular bed. Circ Res 46: 68-77
21. Folkow B, Hallback M, Lundgren Y, Weiss L (1970) Structurally based increase of flow resistance in spontaneously hypertensive rats. Acta Physiol Scand 79: 373-379
22. Fujii AM, Gelpi RJ, Mirsky I, Vatner SF (1988) Systolic and diastolic dysfunction during atrial pacing in conscious dogs with left ventricular hypertrophy. Circ Res 62: 462-470
23. Goodwin JR (1973) Hypertrophic diseases of the myocardium. Prog Cardiovasc Dis 16:199-238
24. Harris CN, Aronow WS, Parker DP, Kaplan MA (1973) Treadmill stress tests in left ventricular hypertrophy. Chest 63: 353-357
25. Harrison DG, Barnes DH, Hiratzka LF, Eastham CL, Kerber RE, Marcus ML (1985) The effect of cardiac hypertrophy on the coronary circulation. Circulation 71: 1135-1145
26. Hoffman JIE, Spaan JAE (1990) Pressure-flow relations in coronary circulation. Physiol Rev 70: 331-390
27. Holtz J, Restorff W, Bard P, Bassenge E (1977) Transmural distribution of myocardial blood flow and of coronary reserve in canine left ventricular hypertrophy. Basic Res Cardiol 72: 286-292
28. Kanatsuka H, Lamping KG, Eastham CL, Dellsperger KC, Marcus ML (1989) Comparison of the effects of increased myocardial oxygen consumption and adenosine on the coronary microvascular resistance. Circ Res 65: 1296-1305
29. Klocke FJ (1987) Measurements of coronary flow reserve: defining pathophysiology versus making decisions about patient care. Circulation 76: 1183-1189
30. Klocke FJ, Ellis AK, Canty JM (1987) Interpretation of changes in coronary flow that accompany pharmacologic interventions. Circulation 75 (suppl V): V-34-V-38
31. Krams R, Sipkema P, Zegers J, Westerhof N (1989) Contractility is the main determinant of coronary systolic flow impediment. Am J Physiol 257 (Heart Circ Physiol 26): H1936-H1944
32. Marcus ML, Mueller TM, Eastham CL (1981) Effects of short- and long-term left ventricular hypertrophy on coronary circulation. Am J Physiol 241 (Heart Circ Physiol 10): H358-H362
33. Marzilli M, Goldstein S, Sabbah HN, Lee T, Stein PD (1979) Modulating effect of regional myocardial performance on local myocardial perfusion in the dog. Circ Res 45: 634-641
34. McFalls EO, DunckerDJ, Sassen LMA, Gho BCG, Verdouw PD (1991) The effect of antianginal therapy on coronary flow reserve and the maximal flow-pressure relationship in anesthetized swine. J Cardiovasc Pharmacol 18: 827-836
35. Messina LM, Hanley FL, Uhlig PN, Baer RW, Grattan MT, Huffman JIE (1985) Effects of pressure gradients between branches of the left coronary artery on the pressure axis intercept and the shape of steady state circumflex pressure-flow relations in dogs. Circ Res 56: 11-19
36. Mueller TM, Marcus ML, Kerber RE, Young JA, Barnes RW. Abboud FM (1978) Effect of renal hypertension and left ventricular hypertrophy on the coronary circulation. Circ Res 42: 543-549
37. O'Keefe DO, Hoffman JIE, Cheitlin R, O'Neill MJ, Allard JR, Shapkin E (1978) Coronary blood flow in experimental canine left ventricular hypertrophy. Circ Res 43: 43-51
38. Parks M, Manohar M, Lundeen G (1983) Regional myocardial blood flow and coronary vascular reserve in unanesthetized ponies during pacing-induced ventricular tachycardia. J Surg Res 35: 119-131
39. Raff WK, Kosche F, Lochner W (1972) Extravascular coronary resistance and its relation to microcirculation. Influence of heart rate, end-diastolic pressure and maximal rate of rise of intraventricular pressure. Am J Cardiol 29: 590-603
40. Rakusan K, Cheng M, Wicker P, Healy B (1987) Morphometry of coronary arterioles in normal and hypertrophic rat heart. In: Tsuchiya M, Asano M, Mishima Y, Oda M (eds) Microcirculation: An Update, vol 2. International Congress Series 755, Proceedings of 4th World Congress of Microcirculation, pp 185-186
41. Ruffolo Jr RR, Spradlin TA, Pollock GD, Waddell JE, Murphy PJ (1981) Alpha and beta adrenergic effects of the stereoisomers of dobutamine. J Pharmacol Exp Ther 219: 447-452
42. Sabiston Jr DC, Gregg DE (1957) The effect of cardiac contraction on coronary blood flow. Circulation 15: 14-20
43. Satoh S, Maruyama Y, Watanabe J, Keitoku M, Hangai K, Takishima T (1990) Coronary zero flow pressure and intramyocardial pressure in the transiently arrested heart. Cardiovasc Res 24: 358-363
44. Satoh S, Watanabe J, Keitoku M, Itho N, Maruyama Y, Takishima T (1988) Influences of pressure surrounding the heart and intracardiac pressure on the diastolic coronary pressure-flow relation in excised canine heart. Circ Res 63: 788-797
45. Scheel KW, Eisenstein BL, Ingram LA (1984) Coronary, collateral, and perfusion territory responses to aortic banding. Am J Physiol 246 (Heart Circ Physiol 10): H768-H775
46. Strauer BE (1983) Left ventricular dynamics, energetics and coronary hemodynamics in hypertrophied heart disease. Eur Heart J 4 (Suppl A): 137-142
47. Tomanek RJ, Palmer PJ, Pfeiffer GL, Schreiber KL, Eastham CL, Marcus ML (1986) Morphometry of canine coronary arteries arterioles and capillaries during hypertension and left ventricular hypertrophy. Circ Res 58: 38-46
48. Tomanek RJ, Schalk KA, Marcus ML, Harrison DG (1989) Coronary angiogenesis during long-term hypertension and left ventricular hypertrophy. Circ Res 65: 352-359
49. Tomanek RJ, Wrangler RD, Bauer CA (1985) Prevention of coronary vasodilator reserve decrements in spontaneously hypertensive rats. Hypertension 7: 533-540
50. Trimble J, Downey J (1979) Contribution of myocardial contractility to myocardial perfusion. Am J Physiol 236 (Heart Circ Physiol 5): H121-H126
51. Uhlig PN, Baer RW, Vlahakes GJ, Hanley FL, Messina LM, Hoffman JIE (1984) Arterial and venous coronary pressure-flow relations in anesthetized dogs. Evidence for a vascular waterfall in epicardial coronary veins. Circ Res 55: 238-248
52. Vlahakes GJ, Baer RW, Uhlig PN, Verrier ED, Bristow JD, Hoffman JIE (1982) Adrenergic influence in the coronary circulation of conscious dogs during maximal vasodilation with adenosine. Circ Res 51: 371-384
53. Vlodaver Z, Neufeld HN (1968) The coronary arteries in coarctation of the aorta. Circulation 37: 449-454
54. Watanabe J, Maruyama Y, Satoh S, Keitoku M, Takishima T (1987) Effect of the pericardium on the diastolic left coronary pressure-flow relationship in the isolated dog heart. Circulation 75: 670-675