Evidence that the substance P-induced enhancement of pacemaking in lymphatics of the guinea-pig mesentery occurs through endothelial release of thromboxane A2

British Journal of Pharmacology

Volumn 121, Issue 8, 1997, Pages 1589-1596

  Rayner, Sharyn E ^a   Van Helden, Dirk F ^a  

^a UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

Arachidonic acid; Calcium; Constriction rate; Endothelium; Lymphatic vessels; NK1 receptor; Pacemaking; Pertussis toxin; Substance P; Thromboxane A2

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 17ALPHA ETHYNYL 17BETA HYDROXY 5ALPHA ANDROSTANO[3,2 B]PYRIMIDO[1,2 A]BENZIMIDAZOLE; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; ACETYLCHOLINE; ANTIFLAMMIN; CALCIUM ION; FLUO 3 AM; GUANINE NUCLEOTIDE BINDING PROTEIN; IMIDAZOLE; INDOMETACIN; N(G) NITROARGININE; NEUROKININ 1 RECEPTOR; NITRIC OXIDE SYNTHASE; PERTUSSIS TOXIN; PHOSPHOLIPASE A2; SPANTIDE; SUBSTANCE P; THROMBOXANE A2; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM; ENZYME INHIBITION; GUINEA PIG; LYMPH VESSEL; MESENTERY; NONHUMAN; PACEMAKER; PRIORITY JOURNAL; TACHYPHYLAXIS; VASOCONSTRICTION;

ANDROSTANES; ANIMALS; ARACHIDONIC ACID; BENZIMIDAZOLES; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELINS; ENDOTHELIUM, VASCULAR; GUINEA PIGS; INDOMETHACIN; LYMPHATIC SYSTEM; MESENTERY; PERTUSSIS TOXIN; PHOSPHOLIPASES A; SUBSTANCE P; THROMBOXANE A2; VIRULENCE FACTORS, BORDETELLA;

EID: 0030794187     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701306     Document Type: Article

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