G-CSF activates STAT pathways in Kasumi-1 myeloid leukemic cells with the t(8; 21) translocation: Basis for potential therapeutic efficacy

Cytokines, Cellular and Molecular Therapy

Volumn 3, Issue 2, 1997, Pages 75-80

  Da Silva, Nicolas ^a   Meyer Monard, Sandrine ^a   Menot, Marie Laurence ^a   Degos, Laurent ^a   Baruchel, André ^a   Dombret, Hervé ^a   Chomienne, Christine ^a  

^a SAINT LOUIS HOSPITAL   (France)

Author keywords

AML; AML1 ETO; Differentiation therapy; G CSF; STATs

Indexed keywords

CD11B ANTIGEN; CD15 ANTIGEN; CDW65 ANTIGEN; CYTOKINE RECEPTOR; DIFFERENTIATION ANTIGEN; GRANULOCYTE COLONY STIMULATING FACTOR; MICROSOMAL AMINOPEPTIDASE; OLIGONUCLEOTIDE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; STAT1 PROTEIN; STAT3 PROTEIN; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ARTICLE; CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CELL POPULATION; CELL SURVIVAL; CHROMOSOME TRANSLOCATION 8; COMPLEX FORMATION; CONTROLLED STUDY; DIMERIZATION; DRUG EFFECT; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKEMIA CELL; MYELOID LEUKEMIA; PRIORITY JOURNAL;

APOPTOSIS; CELL DIFFERENTIATION; CELL DIVISION; CHROMOSOMES, HUMAN, PAIR 21; CHROMOSOMES, HUMAN, PAIR 8; DNA-BINDING PROTEINS; GRANULOCYTE COLONY-STIMULATING FACTOR; HUMANS; LEUKEMIA, MYELOCYTIC, ACUTE; RECEPTORS, GRANULOCYTE COLONY-STIMULATING FACTOR; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSLOCATION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0030793933     PISSN: 13684736     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Sachs L, Control of normal cell differentiation and the phenotypic reversion of malignancy in myeloid leukemia. Cell (1978) 274: 535-9.
2. Collins SJ, Robertson KA, Mueller L, Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RARα). Mol Cell Biol (1990) 10: 2154-63.
3. Lotan R, Clifford JL, Nuclear receptors for retinoids: mediators for retinoids effects on normal and malignant cells. Biomed Pharmacol (1991) 44: 1-13.
4. Breitman TR, Collins SJ, Keene BR, terminal differentiation of human promyelocytic leukemia cells in primary culture in response to retinoic acid. Blood (1981) 60: 1000-4.
5. Chomienne C, Balitrand N, Cost H et al, Structure-activity relationship of the aromatic retinoids on the differentiation of the human histiocytic lymphoma cell line U937. Leuk Res (1986) 10: 1301-5.
6. Lanotte M, Martin-Thouvenin V, Najman S et al, NB4, a maturation inducible cell line with t(15; 17) marker isolated from a human acute promyelocytic leukemia (M3). Blood (1991) 77: 1080-6.
7. Chomienne C, Ballerini P, Balitrand N et al, All-trans retinoic acid in acute promyelocytic leukemia II. In vitro studies: structure and relationship. Blood (1990) 6: 1710-17.
8. Bennett JM, Catovsky D, Daniel MT et al, Proposals for the classification of the acute leukemias (FAB cooperative group). Br J Haematol (1976) 33: 451-8.
9. Iarson RA, Kondo K, Vardiman JW et al, Evidence for a 15; 17 translocation in every patient with acute promyelocytic leukemia. Am J Med (1984) 76: 827-41.
10. Huang ME, Ye YC, Chen SR et al, Use of all-trans retinoic acid in treatment of acute promyelocytic leukemia. Blood (1988) 72: 567-71.
11. Castaigne S, Chomienne C, Daniel MT et al, All-trans retinoic acid as a differentiation therapy for acute leukemia: I, clinical results. Blood (1990) 76: 1704-10.
12. Touw I, Donath J, Pouwels K et al, Acute myeloid leukemias with chromosomal abnormalities involving the 21q22 region identified by their in vitro responsiveness to interleukin-5. Leukemia (1991) 5: 687-92.
13. Ema H, Kitano K, Suda T et al, In vitro differentiation of leukemic cells to eosinophils in the presence of interleukin-5 in two cases of acute myeloid leukemia with the translocation t(8; 21). Blood (1990) 75: 350-6.
14. Asou H, Tashiro S, Hamamoto K et al, Establishment of a human acute myeloid leukemia cell line (Kasumi-1) with 8; 21 chromosomal translocation. Blood (1991) 77: 2031-6.
15. Kondo S, Okamura S, Asano Y et al, Human granulocyte colony-stimulating factor receptors in acute myelogenous leukemia. Eur J Haematol (1991) 46: 223-30.
16. Tsuchiya H, ElSonbaty SS, Nagano K et al, Acute myloblastic leukemia (ANLL-M2) with t(8; 21)(q22; q22) variant expressing lymphoid but not mycloid surface antigens with a high number of G-CSF receptors. Leuk Res (1993) 17: 375-7.
17. Calabresse C, Barbey S, Venturini L et al, In vitro treatment with retinoids or the topoisomerase inhibitor, VP16, evidences different functional apoptotic pathways in acute promyelocytic cells. Leukemia (1995) 9: 2049-57.
18. Chakraborty A, White SM, Schaefer TS et al, Granulocyte colony-stimulating factor activation of STATα and STATβ in immature normal and leukemic human myeloid cells. Blood (1996) 88: 2442-9.
19. Stacchini A, Fubini L, Gatti E et al, In vivo effect of human granulocyte-macrophage colony-stimulating factor (GM-CSF) on neutrophil GM-CSF receptors. Leukemia (1995) 9: 665-70.
20. Metcalf D, Lineage commitment of hemopoietic progenitor cells in developing blast cell colonies: influence of colony-stimulating factors. Proc Natl Acad Sci USA (1991) 88: 11313-14.
21. Elias L, Van Epps DE, Early effects of G- and GM-CSF upon HL-60 proliferation and differentiation. Leukemia (1988) 2: 763-5.
22. Frank R, Zhang J, Uchida H et al, The AML1/ETO fusion protein blocks trans activation of the GM-CSF promoter by AML1B. Oncogene (1995) 11: 2667-74.
23. Grignani F, Fcrruci PF, Testa U et al, The acute promyelocytic leukemia-specific PML-RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cell. Cell (1993) 74: 423-31.
24. Rousselot P, Hardas B, Castaigne S et al, The PML-RAR gene product of the t(15; 17) translocation inhibits retinoic acid-induced granulocytic differentiation. Oncogene (1994) 9: 545-51.
25. Chomienne C, Balitrand N, Ballerini P et al, All-trans retinoic acid modulates the retinoic acid receptor-α in promyelocytic cells. J Clin Invest (1991) 88: 2150-4.
26. Agadir A, Comic M, Jerome M et al, Characterization of nuclear retinoic acid binding activity in sensitive leukemic cell lines: cell specific uptake of ATRA and RARα protein modulation. Biochem Biophys Res Commun (1995) 213: 112-22.
27. Nagata S, Fukunaga R, Granulocyte colony-stimulating factor and its receptor. Progr Growth Factor Res (1991) 3: 131-41.
28. Nucifora G, Larson RA, Rowley JD, Persistence of the 8; 21 translocation in patients with acute myeloid leukemia type M2 in long term remission. Blood (1993) 82: 712-15.