Pharmacokinetic and pharmacodynamic models of the antistaphylococcal effects of meropenem and cloxacillin in vitro and in experimental infection

Antimicrobial Agents and Chemotherapy

Volumn 41, Issue 10, 1997, Pages 2083-2088

  Mattie, Herman ^a   Zhang, Li Chen ^a,b   Van Strijen, Elisabeth ^a   Sekh, Beate Razab ^a,c   Douwes Idema, Anna E A ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MONASH UNIVERSITY   (Australia)

^c Red Cross Hospital Den Haag   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CLOXACILLIN; MEROPENEM;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERICIDAL ACTIVITY; CALCULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; EXPERIMENTAL INFECTION; FEMALE; MODEL; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030793840     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.41.10.2083     Document Type: Article

References (8)

1. Mattie, H., B. A. R. Sekh, M. L. van Ogtrop, and E. van Strijen. 1992. Comparison of the antibacterial effects of cefepime and ceftazidime against Escherichia coli in vitro and in vivo. Antimicrob. Agents Chemother. 36:2439-2443.
2. Mattie, H., A. M. van Dokkum, L. Brus-Weijer, A. M. Krul, and E. van Strijen. 1990. Antibacterial activity of four cephalosporins in an experimental infection in relation to in vitro effect and pharmacokinetics. J. Infect. Dis. 162:717-722.
3. Moffie, B. G., J. J. Hoogeterp, T. Lim, A. E. Douwes-Idema, and H. Mattie. 1993. Effectiveness of netilmicin and tobramycin against Pseudomonas aeruginosa in vitro and in an experimental tissue infection in mice. J. Antimicrob. Chemother. 31:403-411.
4. Peetermans, W. E., J. J. Hoogeterp, A. M. Hazekamp-van Dokkum, P. J. van den Broek, and H. Mattie. 1990. Antistaphylococcal activities of teicuplanin and vancomycin in vitro and in an experimental infection. Antimicrob. Agents Chemother. 34:1869-1874.
5. Tuomanen, E., R. Cozens, W. Tosch, O. Zak, and A. Tomasz. 1986. The rate of killing of Escherichia coli by β-lactam antibiotics is strictly proportional to the rate of bacterial growth. J Gen Microbiol. 132:1297-1304.
6. Vogelman, B., S. Gudmundsson, J. Leggett, J. Turnidge, S. Ebert, and W. A. Craig. 1988. Correlation of antimicrobial pharmacokinetic parameters with therapeutic efficacy in an animal model. J. Infect. Dis. 158:831-847.
7. Zhang, L.-C., and H. Mattie. 1992. Antistaphylococcal and postantibiotic effect of meropenem and cloxacillin in vitro. Rev. Esp. Quimioter. 5(Suppl. 4):21-25.
8. Zhang, L.-C., and H. Mattie. 1993. Antibiotic and postantibiotic effect of meropenem and cloxacillin against Staphylococcus aureus in vitro and in an experimental infection. Clin. Infect. Dis. 17:550. (Abstract.)