Diltiazem, a calcium antagonist, partly attenuates the effects of dextroamphetamine in healthy volunteers

International Clinical Psychopharmacology

Volumn 12, Issue 2, 1997, Pages 113-120

  Fabian, J E ^a   Silverstone, P H ^a  

^a UNIVERSITY OF ALBERTA HOSPITAL   (Canada)

Author keywords

Calcium channel; Dextroamphetamine; Diltiazem; Mania; Subjective effects

Indexed keywords

DEXAMPHETAMINE; DILTIAZEM;

ADRENERGIC TRANSMISSION; ADULT; ARTICLE; ATTENTION; ATTENUATION; BLOOD PRESSURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG ANTAGONISM; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; MANIA; MOOD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REACTION TIME; SLEEP;

EID: 0030793607     PISSN: 02681315     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004850-199703000-00007     Document Type: Article

References (37)

1. Angrist B, Corwin J, Bartlik B and Cooper T (1987) Early pharmacokinetics and clinical effects of oral dextroamphetamine in normal subjects. Biological Psychiatry, 22, 1357-1368.
2. Aoki K, Sato K, Kondo S and Yamamoto M (1983) Hypotensive effects of diltiazem to normals and essential hypertensives. European Journal of Clinical Pharmacology, 25, 475-480.
3. Blundell J (1985) Psychopharmacology of centrally acting anorectic agents. In: Psychopharmacology and Food (Eds M Sandler and T Silverstone), pp. 71-109. Oxford University Press, Oxford.
4. Brauer LH and de Wit H (1996) Subjective responses to dextroamphetamine alone and after pimozide pretreatment in normal, healthy volunteers. Biological Psychiatry, 39, 26-32.
5. Brown WA, Corriveau DP and Ebert M (1978) Acute psychologic and neuroendocrine effects of dextroamphetamine and methylphenidate. Psychopharmacology, 58, 189-195.
6. Bulbena A and Berrios GE (1993) Cognitive function in the affective disorders: a prospective study. Psychopathology, 26, 6-12.
7. Caillard V (1985) Treatment of mania using a calcium antagonist - preliminary trial. Neuropsychobiology, 14, 23-26.
8. Chaffman M and Brogden RN (1985) Diltiazem: a review of its pharmacological properties and therapeutic efficacy. Drugs, 29, 387-454.
9. Dommisse CS, Schulz SC, Narasimhachari N, Blackard WG and Hamer RM (1984) The neuroendocrine and behavioral response to dextroamphetamine in normal individuals. Biological Psychiatry, 19, 1305-1315.
10. Dubovsky SL (1993) Calcium antagonists in manic-depressive illness. Neuropsychobiology, 27, 184-192.
11. Fischman MW and Foltin RW (1991) Utility of subjective-effects measurements on assessing abuse liability of drugs in humans. British Journal of Addiction, 86, 1563-1570.
12. Fisher RE, Gray R and Johnston D (1990) Properties and distribution of single voltage-gated calcium channels in adult hippocampal neurons. Journal of Neurophysiology 64, 91-104.
13. Fogarty F, Russell JM, Newman SC and Bland RC (1994) Mania. Acta Psychiatrica Scandinavica, 376 (Suppl), 16-23.
14. Garza-Trevino ES, Overall JE and Hollister LE (1992) Verapamil versus lithium in acute mania. American Journal of Psychiatry, 149, 121-122.
15. Goldberg TE, Gold JM, Greenberg R, Griffin S, Schultz SC, Pickar D, Kleinman JE and Weinberger DR (1993) Contrasts between patients with affective disorders and patients with schizophrenia on a neuropsychological test battery. American Journal of Psychiatry, 150, 1355-1362.
16. Goodwin FK and Jamison KR (1990) Manic-depressive Illness, p. 32. Oxford University Press, New York, Oxford.
17. Gordin A, Pohto P, Sundberg S, Nykanen S and Haataja H (1986) Pharmacokinetics of slow-release diltiazem and its effect on atrioventricular conduction in healthy volunteers. European Journal of Clinical Pharmacology, 31, 423-426.
18. Hoebel BG, Hernandez L, Schwartz DH, Mark GP and Hunter GA (1989) Microdialysis studies of brain norepinephrine, serotonin, and dopamine release during ingestive behaviour. Annals of the New York Academy of Sciences, 575, 171-191.
19. Hoschl C and Kozeny J (1989) Verapamil in affective disorders: a controlled, double-blind study. Biological Psychiatry, 25, 128-140.
20. Hoschl C (1991) Do calcium antagonists have a place in the treatment of mood disorders? Drugs, 42, 721-729.
21. Ikeda F, Kono T, Oseko F, Imura H and Endo J (1980) Effects of diltiazem hydrochloride on pressor and steroidogenic actions of angiotensins and norepinephrine in man. Endocrinologia Japonica, 27, 779-784.
22. Jacobs D and Silverstone T (1986) Dextrodextroamphetamine-induced arousal in human subjects as a model for mania. Psychological Medicine, 16, 323-329.
23. Lake CR, Pickar D, Ziegler MG, Lipper S, Slater S and Murphy DL (1982) High plasma norepinephrine levels in patients with major affective disorder. American Journal of Psychiatry, 139, 1315-1318.
24. Lipscombe D, Kongsamut S and Tsien R W (1989) α-Adrenergic inhibition of sympathetic neurotransmitter release mediated by modulation of N-type calcium channel gating. Nature, 340, 639-642.
25. Lovett-Doust JW, Munro A and Christie H (1980) Vascular correlates of circular type manic-depressive disorder. Biological Psychiatry, 15, 741-748.
26. Morel N and Godfraind T (1990) Cerebrovascular effect of calcium antagonists. European Neurology, 30, 10-15.
27. Pazzaglia PJ, Post RM, Ketter TA, George MS and Marangell LB (1993) Preliminary controlled trial of nimodipine in ultra-rapid cycling affective dysregulation. Psychiatric Research, 49, 257-272.
28. Renwart N, Frances H and Simon P (1986) The calcium-entry blockers: anti-manic drugs? Progress in Neuropsychopharmacology and Biological Psychiatry, 10, 717-722.
29. Rowbotham MC, Hooker WD, Mendelson J and Jones RT (1987) Cocaine-calcium channel interactions. Psychopharmacology, 93, 152-154.
30. Saenz-Campos D, Bayes MC, Martin S, Barhonoj MJ and Jane F (1995) Gender related pharmacokinetics of diltiazem in healthy subjects. International Journal of Clinical Pharmacology, Therapy and Toxicology, 33, 397-400.
31. Silverstone PH and Grahame-Smith DG (1992) A review of the relationship between calcium channels and psychiatric disorders. Journal of Psychopharmacology, 6, 462-482.
32. Silverstone PH, Johnson B and Cowen PJ (1992) Does ondansetron attenuate dextroamphetamine-induced behavior in human volunteers? Psychopharmacology, 107, 140-141.
33. Souza VBN, Muir WJ, Walker MR, Glabus MF, Roxborough HM, Sharp CW, Dunan JR and Blackwood DHR (1995). Auditory P300 event-related potentials and neuropsychological performance in schizophrenia and bipolar affective disorder. Biological Psychiatry, 37, 300-310.
34. Van Kammen DP and Murphy DL (1975) Attenuation of the euphoriant and activating effects of d- and -amphetamine by lithium carbonate treatment. Psychopharmacologia (Berlin), 44, 215-224.
35. Wessler I, Dooley DJ, Osswald H and Schlemmer F (1990) Differential blockade by nifedipine and ω-conotoxin GVIA of α-1 and β-1 adrenoceptor-controlled calcium channels on motor nerve terminals of the rat. Neuroscience Letters 108, 173-178.
36. 2 adrenoceptors reduce free calcium by closure of N-type calcium channels. Journal of Neurochemistry 55, 303-310.
37. Zacny J P, Bodker BK and de Wit H (1992) Effects of setting on the subjective and behavioral effects of d-dextroamphetamine in humans. Addictive Behaviors, 17, 27-33.