Langerhans cell histiocytosis of lymph nodes: A morphological assessment of 43 biopsies

Pediatric Pathology and Laboratory Medicine

Volumn 17, Issue 5, 1997, Pages 769-787

  Favara, Biaise E ^a,d   Steele, Ann ^b,c  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c A Children's Hospital   (United States)

^d NONE   (United States)

Author keywords

Granuloma; Histiocytosis; Langerhans cell histiocytosis; Lymph node

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CELL PROLIFERATION; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; EPITHELIOID CELL; FEMALE; GIANT CELL; GRANULOMA; HISTIOCYTE; HISTIOCYTOSIS X; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INFANT; LANGERHANS CELL; LYMPH NODE BIOPSY; MACROPHAGE; MALE; PLOIDY; PRIORITY JOURNAL;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; DNA; EPITHELIOID CELLS; FEMALE; GRANULOMA; HISTIOCYTOSIS, LANGERHANS-CELL; HUMANS; INFANT; LYMPH NODES; LYMPHATIC DISEASES; MALE; MIDDLE AGED; PLOIDIES; S100 PROTEINS;

EID: 0030793592     PISSN: 10771042     EISSN: None     Source Type: Journal    
DOI: 10.1080/107710497174471     Document Type: Article

References (39)

1. Griffith BB, et al. Langerhans cell histiocvtosis histiocvtosis X: A donal proliferativc disease. N Kngl Med 1994:331:154-60.
2. Broadhent V. Egeler RM, Nesbit ME Jr. Langerhans cell histiocvtosis-clinical and epidemiological aspects. BrJ Cancer 1994;70Stippl. 23:S11-S16.
3. Favara BE, Jaffe R. The histopathology of I.angerhans cell histiocytosis. Br Cancer 1994;70Suppl. 23:S17-S23.
4. Risdall R, Dehner 1,1', Duray P, Kobrinsky N, Robison I., Nesbit ME Jr. Histiocvtosis X Langerhans cell histiocytosis: Prognostic role of histopathology. Arch Pathol Lab Med 1980:107:59-63.
5. Ncv.elol 0, Frilenx-Herbet F, Gronicr-Sachot Disseminated histiocvtosis X, analysis of prognostic factors based on a retrospective study of 50 cases. Cancer 1979:44:1824-38.
6. Williams W, Dorfman RF. I.ymphadenopathyas the initial manifestation of histiocvtosis X. Am J Surg Pathol 1979:3:405-21.
7. Motoi M, Helbron D, Kaiserling E. Lennert K. Eosinophilic granuloma of lymph nodes-a variant of histiocytosis X. Histopathology 1980:4:585-606.
8. Reid H, Fox H, Whiitaker JS. Eosinophilic granuloma of lymph nodes. Histopathology 1977:1:31-7.
9. Morgenfeld MC., Schajowic/ F. Solitary eosinophilic granuloma of lymph node: Five year folknv-up. Pediatrics 1971;48:301-5.
10. T'ai-Hin C, Ch'nng-ynan C. Eosinophilic grannloma of Ivmph nodes and soft tissues: Report of 21 cases. Chin MedJ 1962:81:384-7.
11. Henry K. Lymph nodes. In: Henry K.SymmersWStC.eds. Systemic Pathology. Thymus, Lymph Nodes. Spleen and Lymphatics. Vol. 7. London: Churchill I.ivingstone. 1992:141-325.
12. Emile JF, Wechsler, Brousse N, el al. Langerhans' cell histiocytosis. Definitive diagnosis with the use of the monoclonal antibody 010 on routinely paraffin-embedded samples. Am J Surg Pathol 1994: 19:636-41.
13. Writing Group of the Histiocvte Society'. Histiocytosis svndromes in children. Lancet 1987:1:208-9.
14. Favara BE, Steele A, GrantJH, Steele P. Adrenal cytomegaly: Quantitative assessment by image analysis. Pediatr Pathol 1991;! 1:521-36.
15. Haag MM, Avet-Loiseau H, Favara BE, Steele A, Smith J, Pallavicini MG. Evaluation of a series of cases of Langerhans cell histiocytosis by comparative genomic hybridization. Presented at the 6th International Workshop on Chromosomes in Solid Tumors, Tucson, Arizona, February 19-21, 1995.
16. HermsenMAJAJiejerGA, BaakJPA,JoenjeH,WalboomersJM. Comparative genomic hybridization: A new tool in cancer pathology. Hum Pathol 1996;27:342-9.
17. Hage C, Willman CL, Favara BE, Isaason P. Langerhans cell histiocytosis histiocytosis X. Immunophenotype and growth fraction. Hum Pathol 1993;24:840-5.
18. McClain K.Jin H.GresikV, Favara B. Langerhans cell histiocytosis, lack of viral etiology. AmJ Hematol 1994;47:16-20.
19. Ladisch S, Gadner H. Treatment of Langerhans cell histiocytosis-evolution and current approaches. BrJ Cancer 1994;70Suppl. 23:S41-S46.
20. Favara BE. Histopathology of the liver in histiocytosis syndromes. Pediatr Pathol 1996; 16:413-33.
21. Lieberman PH. Jones CR, Steinman RM, et al. Langerhans cell eosinophilic granulomatosis: Clinicopathologic study encompassing 50 years. AmJ Surg Pathol 1996;20:519-52.
22. Lichtenstein I. Histiocytosis X eosinophilic granuloma of bone, Letterer-Siwe disease and HandSchüller-Christian disease. Further observations of pathological and clinical importance. J Bone Joint Surg Am 1964;46:76-90.
23. Kadin ME, Donaldson DD, Dorfman RF. Isolated granulomas in Hodgkin's disease. N Engl J Med 1970:283:859-861.
24. Hesseling PB, Wessels G, Egeler RM, Rossouw DJ. Simultaneous occurrence of viral-associated hemophagocytic syndrome and Langerhans cell histiocytosis. Pediatr Hematol Oncol 1995; 12:135-41.
25. Kannourakis G, Abbas A. The role of cytokines in the pathogenesis of Langerhans cell histiocytosis. BrJ Cancer 1994;70Suppl. 23:S37-S40.
26. Ornvold K, Carstensen H, Larsen K, Christinsen IJ, Ralfkiaer E. Flow cytometic DNA analysis of lesions from 18 children with Langerhans cell histiocytosis histiocytosis X. Am J Pathol 1990; 136:1301-7.
27. Rabkin MS, Wittwer CT, Kjeldsberg CR, Picpkorn MW. Flow cytometric DNA content of histiocytosis X Langerhans cell histiocytosis. AmJ Pathol 1988;131:283-9.
28. Willman CL. Detection of clonal histiocytes in Langerhans cell histiocytosis: Biology and clinical significance. BrJ Cancer 1994;70Suppl. 23:S29-S33.
29. Paulli M, Bergamaschi G, Tonon L, et al. Evidence of a polyclonal nature of the cell infiltrate in sinus histiocytosis with massive lymphadenopathy Rosai-Dorfman disease. BrJ Haematol 1995;91:l-4.
30. Burns BF, Colby T, Dorfman RD. Langerhans cell granulomatosis histiocytosis X associated with malignant lymphotnas. AmJ Surg Pathol 1983;7:529-33.
31. Egeler RM, Neglia JP, Arico M, Favara BE, Heitger A, Nesbit ME. Acute leukemia in association with Langerhans cell histiocytosis. Med Pediatr Oncol 1994;23:81-5.
32. Colasante A, Castrilli G, Bianca F, Aiello B, Brtinetti M, Musiani P. Role of cytokines in distribution and differentiation of dendritic cell/Langerhans' cell lineage in human primary carcinomas of the lung. Hum Pathol 1995;26:866-72.
33. Caux C, Massacrier C, De/utter-Dambuyant G, et al. Human dendritic Langerhans cells generated in vitro from CD34+ progenitors can prime naive CD4+ T cells and process soluble antigen. J Immunol 1995; 155:5427-35.
34. Szabolcs P, Avigan D, Gezelter S, et al. Dendritic cells and macrophages can mature independently from a human bone marrow-derived, post-colony-forming unit intermediate. Blood 1996;87: 4520-30.
35. Emile JF, Fraitag S, Andry P, Leborgne M, I.ellouch-Tubiana A, Brousse N. Expression of GM-CSF receptor by Langerhans' cell histiocytosis cells. Virchows Arch A 1995:427:125-9.
36. deGraaf JH, Tamminga RYJ, Kamps WA, Timens W. Langerhans' cell histiocytosis: Expression of leukocyte cellular adhesion molecules suggests abnormal homing and differentiation. AmJ Pathol 1994;144:466-72.
37. I.eahy MA, Krejci SM, Friednash M, et al. Human herpesvirus 6 is present in lesions of Langerhans cell histiocytosis. Invest Dermatol 1993:101:642-5.
38. Mierau GW, Wills EJ, Steele PO. Ultrastructural studies in I.angerhans cell histiocytosis: A search i'or evidence of viral etiology. Pediatr Pathol 1994:14:895-904.
39. McClain K, Weiss RA. Viruses and Langerhans cell histiocvtosis: Is there a link.- Br J Cancer 1994;70Suppl. 2.3:S34-S36.