Concentration of enrofloxacin in equine tissues after long term oral administration

Journal of Veterinary Pharmacology and Therapeutics

Volumn 20, Issue 5, 1997, Pages 402-404

  Giguere S ^a   Belanger M ^b  

^a UNIVERSITY OF GUELPH   (Canada)

^b UNIVERSITY OF GUELPH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; ENROFLOXACIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOASSAY; BLADDER; BRAIN; COLON; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG FECES LEVEL; DRUG TISSUE LEVEL; ESCHERICHIA COLI; FEMALE; HEART; HORSE; ILEUM; KIDNEY; LENS; LIVER; LUNG; MALE; MAMMARY GLAND; MUSCLE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SKIN; SPLEEN; STOMACH; TABLET; UTERUS; VITREOUS BODY;

ANIMALIA; EQUIDAE; EQUUS CABALLUS; ESCHERICHIA COLI;

EID: 0030792799     PISSN: 01407783     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2885.1997.00071.x     Document Type: Article

References (14)

1. Berg, J.N. (1988) Clinical indications for enrofloxacin in domestic animals and poultry. In Proceedings of Western Veterinary Conference, pp. 25-33. Las Vegas, USA.
2. Boothe, D.M. (1994) Enrofloxacin revisited. Veterinary Medicine, 89, 744-753.
3. Ensink, J.M., Van Klingeren, B., Houwers, D.J., Klein, W.R. & Vulto, A.G. (1993) In-vitro susceptibility to antimicrobial drugs of bacterial isolates from horses in The Netherlands. Equine Veterinary Journal, 25, 309-313.
4. Giguère, S., Sweeney, R.W. & Bélanger, M. (1996) Pharmacokinetics of enrofloxacin in adult horses and concentration of the drug in serum, body fluid and endometrial tissues after repeated intragastrically administered doses. American Journal of Veterinary Research, 57, 1025-1030.
5. Heath, S.E. & Townsend, H.G.G. (1989) Chronic pleuritis in a horse. Canadian Veterinary Journal, 30, 69.
6. Langston, V.C., Sedrish, S. & Boothe, D.M. (1996) Disposition of single-dose oral enrofloxacin in the horse. Journal of Veterinary Pharmacology and Therapeutics, 19, 316-319.
7. Moore, R.M., Schneider, R.K., Kowalski, J., Bramlage, L.R., Mecklenburg, L.M. & Kohn, C.W. (1992) Antimicrobial susceptibility of bacterial isolates from 233 horses with musculoskeletal infection during 1979-1989. Equine Veterinary Journal, 24, 450-456.
8. Nix, D.E., Goodwin, S.D., Peloquin, C.A., Rotella, D.L. & Schentag, J.J. (1991) Antibiotic tissue penetration and its relevance: Impact of tissue penetration on infection response. Antimicrobial Agents and Chemotherapy, 35, 1953-1959.
9. Prescott, J.F. & Yielding, K.M. (1990) In vitro susceptibility of selected veterinary bacterial pathogens to ciprofloxacin, enrofloxacin and norfloxacin. Canadian Journal of Veterinary Research, 54, 195-197.
10. Prescott, J.F. & Baggot, J.D. (1993) Fluoroquinolones. In Antimicrobial therapy in veterinary medicine. Eds Prescott, J.F. & Baggot, J.D. 2nd edn. Iowa State University Press, Ames, USA, pp. 37-60.
11. Pyörälä, S., Panu, S. & Kaartinen, L. (1994) Single-dose pharmacokinetics of enrofloxacin in horses. In Proceedings of 6th Conference of European Association for Veterinary Pharmacology and Toxicology, pp. 45-46. Edinburgh, UK.
12. Rodger, L.D., Carlson, G.P., Moran, M.E., Yarbrough, T.B., Pascoe, J.R. & Reynolds, J.A. (1995) Resolution of a left urethral stone using electrohydraulic lithotripsy in a thoroughbred colt. Journal of Veterinary Internal Medicine, 9, 280-282.
13. Scheer, M. (1987) Concentration of active ingredient in the serum and tissues after oral and parenteral administration of Baytril. Veterinary Medical Review, 2, 104-118.
14. Schentag, J.J. & Gengo, F.M. (1982) Principles of antibiotic tissue penetration and guidelines for pharmacokinetic analysis. Medical Clinics of North America, 66, 39-49.