An updated meta-analysis of formaldehyde exposure and upper respiratory tract cancers

Journal of Occupational and Environmental Medicine

Volumn 39, Issue 7, 1997, Pages 639-651

  Collins, James J ^a   Acquavella, John F ^a   Esmen, Nurtan A ^b  

^a MONSANTO COMPANY   (United States)

^b Monsanto Company A2SL ^*

Author keywords

[No Author keywords available]

Indexed keywords

FORMALDEHYDE;

ARTICLE; CANCER RISK; CASE CONTROL STUDY; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; META ANALYSIS; NASOPHARYNX CANCER; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; PARANASAL SINUS CANCER; UPPER RESPIRATORY TRACT;

CARCINOGENS, ENVIRONMENTAL; FEMALE; FORMALDEHYDE; HUMANS; MALE; OCCUPATIONAL DISEASES; RESPIRATORY TRACT NEOPLASMS;

EID: 0030792312     PISSN: 10762752     EISSN: None     Source Type: Journal    
DOI: 10.1097/00043764-199707000-00009     Document Type: Article

References (99)

1. Consensus Workshop on Formaldehyde. Report on the consensus workshop on formaldehyde. Environ Health Perspect. 1984;58:323-381.
2. Levine RJ, Andjelkovich DA, Shaw LK. The mortality of Ontario undertakers and a review of formaldehyde-related mortality studies. J Occup Med. 1984;26:740-746.
3. Blair A, Walrath J, Malker H. Review of epidemiologic evidence regarding cancer and exposure to formaldehyde. In: Turoski V, ed. Formaldehyde - Analytical Chemistry and Toxicology. Washington, DC: American Chemical Society; 1985: 261-273.
4. Hopkins J. Formaldehyde epidemiology: a mouthful of uncertainty. Fd Chem Toxic. 1986;23:1024-1026.
5. Nelson N, Levine RJ, Albert RE, Blair AE, Griesemer RA, Landrigan PJ, Stayner LT, Swenberg JA. Contribution of formaldehyde to respiratory cancer. Environ Health Perspect. 1986;70:23-35.
6. Universities Associated for Research and Education in Pathology, Inc. Epidemiology of chronic occupational exposure to formaldehyde: report of the ad hoc panel on health aspects of formaldehyde. Toxicol Ind Health. 1988;4:77-90.
7. Greenblatt M. Formaldehyde toxicology: a review of recent research and regulatory changes. Lab Med. 1988;19:425-428.
8. McLaughlin JK. Formaldehyde and cancer: a critical review. Int Arch Occup Environ Health. 1994;66:295-301.
9. Purchase IFH, Paddle GM. Does formaldehyde cause nasopharyngeal cancer in man? Cancer Lett. 1989;46:79-85.
10. International Program on Chemical Safety. Environmental Health Criteria 89: Formaldehyde. Geneva: World Health Organization; 1989.
11. Blair A, Saracci R, Stewart PA, Hayes RB, Shy C. Epidemiologic evidence on the relationship between formaldehyde exposure and cancer. Scand J Work Environ Health. 1990;16:381-393.
12. Partanen, T. Formaldehyde exposure and respiratory cancer - a meta-analysis of the epidemiologic evidence. Scand J Environ Health. 1993;19:8-15.
13. International Agency for Research on Cancer. Formaldehyde. IARC Monogr Eval Carcinog Risks Hum. 1995;62:217-365.
14. Kerns WD, Pavkov KL, Dondfrio DJ, Gralla EJ, Swenberg JA. Carcinogenicity of formaldehyde in rats and mice after long-term, inhalation exposure. Cancer Res. 1983;43:4382-4392.
15. Swenberg JA, Gross EA, Randall HW, Barrow CS. The effect of formaldehyde exposure on cytotoxicity and cell proliferation. In: Clary JJ, Gibson JE, Waritz RS, eds. Formaldehyde: Toxicology, Epidemiology, Mechanisms. New York: Marcel Dekker; 1982:225-236.
16. Starr TB. Quantitative cancer risk estimation for formaldehyde. Risk Anal. 1990; 10:85-91.
17. Heck HA, Casanova M, Steinhagen WH, Everitt JI, Morgan KT, Popp JA. Formaldehyde toxicity: DNA protein crosslinking studies in rats and nonhuman primates. In: Feron VJ, Bosland MC, eds. Nasal Carcinogenesis in Rodents: Relevance to Human Health Risk. Wageningen, The Netherlands: PUDOC; 1989: 159-164.
18. National Center for Health Statistics. Vital Statistics of the United States, 1985, Volume II, Mortality, Part A. [DHHS Publication No. (PHS) 88-1101.] Washington, DC: Public Health Service, US Government Printing Office; 1988.
19. Stayner LT, Elliot L, Blade L, Keenlyside R, Halperin W. A retrospective cohort mortality study of workers exposed to formaldehyde in the garment industry. Am J Ind Med. 1988;13:667-681.
20. Costantini AS, Paci E, Miligi L, Buiatti E, Martelli C, Lenzi S. Cancer mortality among workers in the Tuscan tanning industry. Br J Ind Med. 1989;46:384-388.
21. Edling C, Jarvholm B, Andersson L, Axelson O. Mortality and cancer incidence among workers in an abrasive manufacturing industry. Br J Ind Med. 1987;44:57-59.
22. Hagmar L, Bellander T, Englander V, Ranstam J, Atwell R, Skerfving S. Mortality and cancer morbidity among workers in a chemical factory. Scand J Work Environ Health. 1986;12:545-551.
23. Wong O. An epidemiologic mortality study of a cohort of chemical workers potentially exposed to formaldehyde with a discussion on SMR and PMR. In: Gibson JE, ed. Formaldehyde Toxicity. New York: Hemisphere Publishing Co.; 1983: 256-272.
24. Acheson ED, Gardner MJ, Pannett B, Barnes HR, Osmond C, Taylor CP. Formaldehyde in the British chemical industry. Lancer. 1984;1:611-616.
25. Stayner LT, Smith AB, Reeve G, Balde L, Elliott L, Keenlyside R, Halperin W. Proportionate mortality study of workers in the garment industry exposed to formaldehyde. Am J Ind Med. 1985;7:229-240.
26. Liebling T, Rosenman KD, Pastides H, Griffith RG, Lemeshow, S. Cancer mortality among workers exposed to formaldehyde. Am J Ind Med. 1984;5:423-428.
27. Marsh GM. Proportional mortality patterns among chemical plant workers exposed to formaldehyde. Br J Ind Med 1082;39:313-322.
28. Jiang X, Zhang R. The toxicity and potential risk of occupational exposure to formaldehyde. Occup Health Shanghai. 1988;2:70-74.
29. Blair A, Stewart PA, O'Berg M, Gaffey W, Walrath J, Ward J, Bales R, Kaplan S, Cubit D. Mortality among industrial workers employed in the formaldehyde industry. J Natl Cancer Inst. 1986;76: 1071-1084.
30. Gardner MJ, Pannett B, Winter PD, Cruddas AM. A cohort study of workers exposed to formaldehyde in the British chemical industry: an update. Br J Ind Med. 1993;50:827-834.
31. Bertazzi PA, Pesatori AC, Radice L, Zocchetti C, Vai T. Exposure to formaldehyde and cancer mortality in a cohort of workers producing resins. Scand J Work Environ Health. 1986;12:461-468.
32. Bertazzi PA, Pesatori A, Guercilena S, Consonni D, Zocchetti C. Rischio cancerogeno per I produttori di resine esposti a formaldeide: estensione de follow-up. Med Lav. 1989;80:111-122.
33. Andjelkovich DA, Janszen DB, Brown MH, Richardson RB, Miller FJ. Mortality of iron foundry workers IV: analysis of a subcohort exposed to formaldehyde. J Occup Environ Med. 1995, in press.
34. Marsh GM, Stone RA, Esmen NA, Henderson VL. Mortality patterns among chemical plant workers exposed to formaldehyde and other substances. J Natl Cancer Inst. 1994;86:384-386.
35. Kreiger N. Formaldehyde and nasal cancer mortality. Can Med Assoc. 1983;128: 248-249.
36. Zheng XS, Jiang YX. A preliminary report on the analysis of malignant mortality among anatomists and their assistants. Occup Health Shanghai. 1988;2:89-90.
37. Logue JN, Barrick MK, Jessup GL. Mortality of radiologists and pathologists in the radiation registry of physicians. J Occup Med. 1986;28:91-99.
38. Harrington JM, Oakes D. Mortality study of British pathologists 1974-80. Br J Ind Med. 1984;41:188-191.
39. Hall A, Harrington JM, Tar-Ching A. Mortality study of British pathologists. Am J Ind Med. 1991;20:83-89.
40. Harrington JM, Shannon HS. Mortality study of pathologists and medical laboratory technicians. Br Med J. 1975;8:329-332.
41. Stroup NE, Blair A, Erikson GE. Brain cancer and other causes of death in anatomists. J Natl Cancer Inst. 1986;77: 1217-1224.
42. Matanoski GM. Risk of Pathologists Exposed to Formaldehyde. [NTIS/PB91-173682.] Springfield, VA: National Technical Information Service; 1991.
43. Walrath J, Fraumeni JF. Mortality patterns among embalmers. Int J Cancer. 1983;31:407-411.
44. Walrath J, Fraumeni JF. Cancer and other causes of death among embalmers. Cancer Res. 1984;44:4638-4641.
45. Hayes RB, Blair A, Stewart PA, Herrick RF, Mahar H. Mortality of U.S. embalmers and funeral directors. Am J Ind Med. 1990;18:641-652.
46. West S, Hildesheim A, Dosemeci M. Non-viral risk factors for nasopharyngeal carcinoma in the Philippines: results from a case-control study. Int J Cancer. 1993; 55:722-727.
47. Luce D, Gerin M, Leclerc A, Morcet JF, Brugere J, Goldberg M. Sinonasal cancer and occupational exposure to formaldehyde and other substances. Int J Cancer. 1993;53:224-231.
48. Olsen JH, Asnaes S. Formaldehyde and the risk of squamous cell carcinoma of the sinonasal cavities. Br J Ind Med. 1986;43:769-774.
49. Olsen JH, Plough-Jensen S, Hink M, Faurbo K, Breum NO, Moller-Jensen O. Occupational formaldehyde exposure and increased nasal cancer risk in man. Int J Cancer. 1984;34:639-644.
50. Hayes RB, Raatgever JW, Bruyn AD, Gerin M. Cancer of the nasal cavity and paranasal sinuses, and formaldehyde exposure. Int J Cancer. 1986;37:487-492.
51. Roush GC, Walrath J, Stayner LT, Kaplan SA, Flannery JT, Blair A. Nasopharyngeal cancer, sinonasal cancer, and occupations related to formaldehyde: a case-control study. J Natl Cancer Inst. 1987;79:1221-1224.
52. Vaughan TL, Strader C, Davis S, Daling JR. Formaldehyde and cancers of the pharynx, sinus and nasal cavity: I. Occupational exposures. Int J Cancer. 1986; 38:677-683.
53. Vaughan TL, Strader C, Davis S, Daling JR. Formaldehyde and cancers of the pharynx, sinus, and nasal cavity: II. residential exposures. Int J Cancer. 1986; 38:685-688.
54. Brinton LA, Blot WJ, Backer JA, Winn DM, Browder JP, Farmer JC, Fraumeni JF. A case-control study of cancers of the nasal cavity and paranasal sinuses. Am J Epidemiol 1984;119:896-906.
55. Brinton LA, Blot WJ, Fraumeni JF. Nasal cancer in the textile and clothing industries. Br J Ind Med. 1985;42:469-474.
56. Jensen OM, Andersen SK. Lung cancer risk from formaldehyde. Lancet. 1982;1: 913.
57. Fayerweather WE, Pell S, Bender JR. Case control study of cancer deaths in Du Pont workers with potential exposure to formaldehyde. In: Clary JJ, Gibson JE, Waritz RS, ed. Formaldehyde: Toxicology, Epidemiology, Mechanisms. New York: Marcel Dekker, Inc; 1983:47-125.
58. Coggon D, Pannett B, Acheson ED. Use of job-exposure matrix in an occupational analysis of lung and bladder cancers on the basis of death certificates. J Natl Cancer Inst. 1984;72:61-65.
59. Bond G, Flores GH, Shellenberger RJ, Cartmill JB, Fishbeck WA, Cook RR. Nested case-control study of lung cancer among chemical workers. Am J Epidemiol. 1986;124:53-66.
60. Gerin M, Siemiatycki J, Nadon L, Dewar R, Krewski D. Cancer risks due to occupational exposure to formaldehyde: results of a multi-site case-control study in Montreal. Ins J Cancer. 1989;44:53-58.
61. Partanen T, Kauppinen T, Nurminen M, Nickels J, Hernberg S, Hakulinen T, Pukkala E, Savonen E. Formaldehyde exposure and respiratory and related cancers: a case referent study among Finnish woodworkers. Scand J Work Environ Health. 1985;11:409-415.
62. Partanen T, Kauppinen T, Hernberg S, Nickels J, Luukkonen R, Hakulinen T, Pukkala E. Formaldehyde exposure and respiratory cancer among woodworkers: an update. Scand J Work Environ Health. 1990;16:394-400.
63. Chiazze L, Watkins DK, Fryar C, Kozono J. A case-control study of malignant and non-malignant respiratory disease among employees of a fiberglass manufacturing facility: II. Exposure assessment. Br J Ind Med. 1993;50:717-725.
64. Hernberg S, Collan Y, Degerth R, Englund A, Engzell U, Kuosma, E, Mutanen P, Nordlinder H, Hansen HS, Schultz-Larsen K, Sogaard H, Westerholm P. Nasal cancer and occupational exposure. Scand J Work Environ Health. 1983;9: 208-213.
65. Hernberg S, Westerholm P, Schultz-Larsen K, Degerth R, Kuosma, E, Englund A, Engzell U, Hansen HS, Mutanen P. Nasal and sinonasal cancer. Scand J Work Environ Health. 1983;9: 315-326.
66. Bemadini P, Carelli G, Rimatori V, Contegiacomo P. Health hazards for hospital workers from exposure to formaldehyde. Med Lav. 1983;74:106-110.
67. Berstein RS, Stayner LT, Elliott LJ, Kimbrough R, Falk H, Blade L. Inhalation exposure to formaldehyde: an overview of its toxicology, epidemiology, monitoring, and control. Am Ind Hyg Assoc J. 1984;45:778-785.
68. Skisak CM. Formaldehyde vapor exposure in anatomy laboratories. Am Ind Hyg Assoc J. 1983;44:948-950.
69. Kerfoot EJ, Mooney TF. Formaldehyde and paraformaldehyde study in funeral homes. Am Ind Hyg Assoc J. 1975;45: 172-176.
70. Williams TT, Levine RJ, Blunden PB. Exposure to embalmers to formaldehyde and other chemicals. Am Ind Hyg Assoc. 1984;45:172-176.
71. Ahmen M, Alexandersson R, Elkholm U, Bergstrom B, Dahlqvist M, Ulfvasson I. Impeded lung function in moulders and core makers handling furan resin sand. Int Arch Occup Environ Health. 1991;63: 175-180.
72. Alexandersson R, Hedenstierna G. Respiratory hazards associated with exposure to formaldehyde and solvents in acid-curing plants. Arch Occup Environ Health. 1988;43:222-227.
73. Kauppinen TP, Niemela RI. Occupational exposure to chemical agents in the particleboard industry. Scand J Work Environ Health. 1985;11:357-363.
74. Stumpf JM, Blehm KD, Buchan RM, Gunther BJ. Characterization of particle board aerosol: size distribution and formaldehyde content. Am Ind Hyg Assoc J. 1986;47:725-730.
75. Niemala R, Vanio H. Formaldehyde exposure in work and the general environment: occurrence and possibilities for prevention. Scand J Work Environ Health. 1981;7:95-100.
76. Malaka T, Kodama AM. Respiratory health of plywood workers occupationally exposed to formaldehyde. Arch Environ Health. 1990;45:288-294.
77. Kauppinen T. Occupational exposure to chemical agents in the plywood industry. Ann Occup Hyg. 1986;30:19-29.
78. Priha E, Riipinen H, Korhonen K. Exposure to formaldehyde and solvents in Finnish furniture factories: 1975-1984. Ann Occup Hyg. 1986;30:289-294.
79. Rosen G, Andersson I, Juring L. Reduction of exposure to solvent and formaldehyde in surface coating operations in the wood working industry. Ann Occup Hyg. 1990;34:293-303.
80. Sass-Kortsak AM, Holness DL, Pilger CW, Nethercott JR. Wood dust and formaldehyde exposures in cabinet making industry. Am Ind Hyg Assoc J. 1986;47: 747-753.
81. Riala REE, Riihimaki HA. Solvent and formaldehyde exposure in parquet and carpet work. Appl Occup Environ Hyg. 1991;6:301-308.
82. Lewis P. Report of airborne solvent concentrations in a printing ink manufacturing plant in Cape Town, Republic of South Africa. Appl Occup Environ Hyg. 1994;9:147-151.
83. Gockel DL, Horstman SW, Scott CM. Formaldehyde emissions from carbonless copy paper forms. Am Ind Hyg Assoc J. 1981;42:474-476.
84. Stewart PA, Cubit D, Blair A. Formaldehyde levels in seven industries. Appl Ind Hyg. 1987;2:231-236.
85. Stumph JM, Blehm KD, Bucham RM, Gunther BJ. Characterization of particle board aerosol: size distribution and formaldehyde content. Am Ind Hyg Assoc J. 1986;47:725-730.
86. Pisaniello DL, Cornell KE, Muriele L. Wood dust exposure during furniture manufacture: results from an Australian survey and consideration for threshold limit value development. Am Ind Hyg Assoc J. 1991;52:485-492.
87. Luker MA, van Houten RW. Control of formaldehyde in a garment sewing plant. Am Ind Hyg Assoc J. 1990;51:541-544.
88. Greenland S. Quantitative methods in the review of epidemiologic literature. Epidemiol Rev. 1987;9:1-30.
89. Poole C. Beyond the confidence interval. Am J Public Health. 1987;77:195-199.
90. 41]
91. Blair A, Stewart PA, Hoover RN, Fraumeni JF, Walrath J, O'Berg M, Gaffey W. Cancers of the nasopharynx and oropharynx and formaldehyde exposure. J Natl Cancer Inst. 1987;78:191-192.
92. Collins JJ, Caporossi JC, Utidjian HM. Cancers of the nasopharynx and oropharynx and formaldehyde exposure. J Natl Cancer Inst. 1987;78:192-193.
93. Lucas LJ. Misclassification of nasopharyngeal cancer. J Natl Cancer Inst. 1994; 86:1556-1557.
94. Percy CL, Miller BA, Gloeckler Reis LA. Effect of changes in cancer classification and the accuracy of cancer death certificates on trends in cancer mortality. In: Davis DL, Hoel D, eds. Trends in Cancer Mortality in Industrial Countries. New York: New York Academy of Sciences; 1990.
95. Hildesheim A, West A, Deveyra E, de Guzman MF, Jurado A, Jones C, Imai J, Hinuma Y. Herbal medicine use, Epstein-Barr virus and risk of nasopharyngeal carcinoma. Cancer Res. 1992;52:3048-3051.
96. Buncher CR. Did formaldehyde cause lung cancer? J Occup Med. 1989;31:885.
97. Callas PW, Pastides H, Hosmer DW. Lung cancer mortality among workers in formaldehyde industries. J Occup Environ Med. 1996;38:747-748.
98. Sterling TD, Weinkam JJ. Response: lung cancer mortality among workers in formaldehyde industries. J Occup Environ Med. 1996;38:749-750.
99. Stone RA, Marsh GM, Henderson VL. Response: lung cancer mortality among workers in formaldehyde industries. J Occup Environ Med. 1996;38:751.