Effects of natural ageing on plasma 5-HT turnover in humans

Human Psychopharmacology

Volumn 12, Issue 4, 1997, Pages 365-367

  Dursun, S M ^a,b   Whitaker, R P ^a   Andrews, H ^a   Reveley, M A ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Ageing; Human; Serotonin; Serotonin turnover

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; SEROTONIN;

ADULT; AGING; ALZHEIMER DISEASE; ARTICLE; CELL DEGENERATION; CONTROLLED STUDY; DEMENTIA; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL; SEROTONIN RELEASE; SEROTONINERGIC SYSTEM; VOLUNTEER;

EID: 0030792292     PISSN: 08856222     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1077(199707/08)12:4<365::AID-HUP879>3.0.CO;2-2     Document Type: Article

References (11)

1. Bearcroft, C. P., Farthing, M. J. G. and Perret, D. (1995). Determination of 5-hydroxytryptamine, 5-hydroxyindoleacetic acid and tryptophan in plasma and urine by HPLC with fluorimetric detection. Biomedical Chromatography, 9, 23-27.
2. Gonzales, G. F. and Carrillo, C. (1993). Blood serotonin levels in postmenopausal women: Effects of age and serum oestradiol levels. Maturitas, 17, 23-29.
3. Huguet, F., Drieu, K. and Piriou, A. (1994) Decreased cerebral 5-HT1A receptors during ageing: Reversal by Ginkgo Extract (EGb 761). Journal of Pharmacy and Pharmacology, 46, 316-318.
4. Kabuto, H., Yokoi, I., Mori, A., Murakami, M. and Sawada, S. (1995). Neurochemical changes related to ageing in the senescence-accelerated mouse brain and the effect of chronic administration of nimodipine. Mechanical Ageing & Development, 21, 1-9.
5. Lawlor, B. A., Sunderland, T., Mellow, A. M., Hill, J. L., Molchan, S. E. and Murphy, D. L. (1989). Hyperresponsivity to the serotonin agonist m-chlorophenyl-piperazine in Alzheimer's disease: A controlled study. Archives of General Psychiatry, 46, 542-549.
6. McBride, P. A., Tiernev, H., De Meom, M., Chen, J. S. and Mann, J. (1990). Effects of age and gender on CNS serotonergic responsivity in normal adults. Biological Psychiatry, 27, 1143-1155.
7. Parnetti, L., Reboldi, G. P., Santucci, C., Santucci, A., Gaiti, A., Brunetti, M., Cecchetti, R. and Senin, U. (1994). Platelet MAO-B activity as a marker of behavioural characteristics in dementia disorders. Aging, 6, 201-207.
8. Rodriguez-Gomez, J. A., de la Roza, C., Machado, A. and Cane, J. (1995). The effect of age on the monoamines of the hypothalamus. Mechanical Ageing & Development, 77, 185-195.
9. Stahl, S. M. (1985). Platelets as pharmacological models for the receptors and biochemistry of monoaminergic neurons. In: Platelets: Physiology and Pharmacology, Longenecker, G. L. (Ed.), Academic Press, New York, pp. 307-340.
10. Venero, J. L., Machado, A. and Cane, J. (1993). Effect of ageing on monoamine turnover in the prefrontal cortex of rats. Mechanical Ageing & Development, 72, 105-118.
11. Weil-Fugazza, J., Godefray, F. and Stupfel, M. (1980). Relation of sex and ageing to serotonin metabolism in rats. Mechanical Ageing & Development, 13, 199-204.