Development of a freeze-dried albumin-free formulation of recombinant factor VIII SQ

Pharmaceutical Research

Volumn 14, Issue 7, 1997, Pages 892-898

  Österberg, Thomas ^a,c   Fatouros, Angelica ^a   Mikaelsson, Marianne ^b  

^a Pharmacia and Upjohn AB ^*  (Sweden)

^b PFIZER INC   (United States)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

Factor VIII; Formulation; Freeze dried; Protein stability; Surface adsorption

Indexed keywords

BLOOD CLOTTING FACTOR 8; RECOMBINANT BLOOD CLOTTING FACTOR 8;

ARTICLE; DRUG FORMULATION; FREEZE DRYING; PRIORITY JOURNAL; PROTEIN STABILITY;

ADSORPTION; ALBUMINS; BUFFERS; COLD; DRUG STABILITY; FACTOR VIII; FREEZE DRYING; HUMANS; HYDROGEN-ION CONCENTRATION; POLYSORBATES; RECOMBINANT PROTEINS; SODIUM CHLORIDE; SURFACE PROPERTIES; WATER;

EID: 0030792279     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012199816852     Document Type: Article

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