Analysis of a two-stage fermentor with cell recycling for continuous acetic acid production

Journal of Fermentation and Bioengineering

Volumn 83, Issue 6, 1997, Pages 565-570

  Nishiwaki, Akio ^a  

^a OYAMA NATIONAL COLLEGE OF TECHNOLOGY   (Japan)

Author keywords

Acetic acid fermentation; Cell recycle; Membrane filtration; Two stage fermentor

Indexed keywords

ACETIC ACID; CELL CULTURE; CELLS; FERMENTERS; MATHEMATICAL MODELS; REACTION KINETICS;

CELL RECYCLING; TWO STAGE FERMENTERS;

FERMENTATION;

ACETIC ACID;

ARTICLE; BIOREACTOR; CELL GROWTH; FERMENTATION; MEMBRANE FILTER;

EID: 0030791146     PISSN: 0922338X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0922-338X(97)81138-5     Document Type: Article

References (12)

1. Imanaka, T., Kaieda, T., and Taguchi, H.: Optimization of α-galactosidase production in multi-stage continuous culture of mold. J. Ferment. Technol., 51, 431-439 (1973).
2. Goto, S., Kitai, A., and Ozaki, A.: Continuous yeast cell production from ethanol with a multi-stage tower fermentor. J. Ferment. Technol., 51, 582-593 (1973).
3. Maiorella, B., Wike, C. R., and Blanch, H. W.: Alcohol production and recovery. Adv. Biochem. Eng., 20, 43-92 (1981).
4. Park, Y. S. and Toda, K.: Multi-stage biofilm reactor for acetic acid production at high concentration. Biotechnol. Lett., 14, 609-612 (1992).
5. Lee, S. B., Ryu, D. D. Y., Seigel, R., and Park, S. H.: Performance of recombinant fermentation and evaluation of gene expression efficiency for gene product in two-stage continuous culture system. Biotechnol. Bioeng., 31, 805-820 (1988).
6. Berry, F., Sayadi, S., Nasri, M., Thomas, D., and Barbotin, J. N.: Immobilized and free cell continuous cultures of a recombinant E. coli producing catechol 2,3-dioxygenase in a two-stage chemostat: improvement of plasmid stability. J. Biotechnol., 16, 199-209 (1990).
7. Lee, S., Choi, S., Kim, E., and Koo, Y.: Continuous production of clinical dextran using two-stage reactor. Biotechnol. Lett., 14, 379-384 (1992).
8. Cubarsi, R. and Villaverde, A.: Conditions for a continuous production of transient microbial products in a two-stage fermentation system. Biotechnol. Lett., 15, 827-832 (1993).
9. Park, T. H., Hong, J., and Lim, H. C.: Theoretical analysis of the effect of cell recycling on recombinant cell fermentation processes. Biotechnol. Prog., 7, 77-84 (1991).
10. Boyaval, P., Madec, M. N., and Corre, C.: Concentrated starter productions in a two stage cell-recycle bioreactor plant. Biotechnol. Lett., 14, 589-592 (1992).
11. Nishiwaki, A. and Bourne, J. B.: Performance of a multistage fermentor with cell filtering and recycling for continuous acetic acid production. J. Gen. Appl. Microbiol., 41, 461-473 (1995).
12. Park, Y. S. and Toda, K.: Simulation study on bleed effect in cell-recycle culture of Acetobacter aceti. J. Gen. Appl. Microbiol., 36, 221-233 (1990).