NSAIDS upregulate β2-integrin expression on human neutrophils through a calcium-dependent pathway

Alimentary Pharmacology and Therapeutics

Volumn 11, Issue 3, 1997, Pages 619-630

  Fiorucci, S ^a,d   Santucci, L ^a   Gerli, R ^b   Brunori, P M ^a   Federici, B ^a   Ugolini, B ^a   Fabbri, C ^c   Morelli, A ^a  

^a Dipto Med Clin Patol Farmacol   (Italy)

^b Ist Clin Medica I Sci Oncologiche   (Italy)

^c UNIVERSITY OF PERUGIA   (Italy)

^d POLICLINICO MONTELUCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINO 1 (3 TRIFLUOROMETHYLPHENYL) 2 PYRAZOLINE; CALCIUM; CD11B ANTIGEN; CD18 ANTIGEN; DICLOFENAC; INDOMETACIN; INTEGRIN; IONOMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MYELOPEROXIDASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NONSTEROID ANTIINFLAMMATORY AGENT; PROTEIN KINASE C; PROTEIN TYROSINE KINASE INHIBITOR; SUPEROXIDE; THAPSIGARGIN;

ANTIGEN EXPRESSION; ARTICLE; CALCIUM MOBILIZATION; CELL ADHESION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; NEUTROPHIL; PRIORITY JOURNAL; RHEUMATIC DISEASE; STOMACH DISEASE;

EID: 0030791099     PISSN: 02692813     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2036.1997.00190.x     Document Type: Article

References (59)

1. Ivey KJ. Mechanism of NSAID-induced gastric damage: actions of therapeutic agents. Am J Med 1988; 84(Suppl. 2A): 41-8.
2. Wallace JL, Keenan CM, Granger DN. Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process. Am J Physiol 1990; 259: G462-7.
3. Lee M, Feldman M. Aspirin-induced acute gastric mucosal injury is a neutrophil-dependent process in rats. Am J Physiol 1992; 26: G920-6.
4. Wallace JL, Arfors K-E, McKnight GW. A monoclonal antibody against the CD18 leukocyte adhesion molecule prevents indomethacin-induced gastric damage in the rabbit. Gastroenterology 1991; 100: 878-83.
5. Santucci L, Fiorucci S, Di Matteo FM, Morelli A. Role of tumor necrosis factor-release and leukocyte margination in indomethacin-induced gastric injury in rats. Gastroenterology 1995; 108: 393-401.
6. Granger ND, Kubes P. The microcirculation and inflammation: modulation of leukocyte-endothelial cell adhesion. J Leukoc Biol 1994; 55: 662-75.
7. Hogg N, Berlin C. Structure and function of adhesion receptors in leukocyte trafficking. Immunol Today 1995; 16: 327-30.
8. Yoshida N, Takemura T, Granger N, et al. Molecular determinants of aspirin-induced neutrophil adherence to endothelial cells. Gastroenterology 1993; 105: 715-24.
9. Diaz-Gonzales F, Gonzales-Alvaro I, Campanero MR, et al. Prevention of in vitro neutrophil-endothelial attachment through shedding of L-selectin by nonsteroidal antiinflammatory drugs. J Clin Invest 1995; 95: 1756-65.
10. Smith JA. Neutrophils, host defence, and inflammation: a double-edged sword. J Leukoc Biol 1994; 56: 672-86.
11. Hallett MB, Lloyds D. Neutrophils priming: the cellular signals that say 'amber' but not 'green'. Immunol Today 1995; 16: 264-8.
12. Kishimoto T, Taga T, Akira S. Cytokine signal transduction. Cell 1994; 76: 253-62.
13. Gomes-Cambronero J, Huang C-K, Gomez-Gambronero T-M, et al. Granulocyte-macrophage colony-stimulating factor-induced protein tyrosine phosphorylation of microtubule-associated protein kinase in human neutrophils. Proc Natl Acad Sci USA 1991; 89: 7551-5.
14. McColl SR, DiPersio JF, Caon AC, Ho P, Naccache PH. Involvement of tyrosine kinases in the activation of human peripheral neutrophils by granulocyte-macrofage colony-stimulating factor. Blood 1991; 78: 1842-52.
15. Lew PD, Monod A, Waldvogel FA, et al. Quantitative analysis of the cytosolic free calcium dependency of exocytosis from three subcellular compartments in intact human neutrophils. J Cell Biol 1986; 102: 2197-2204.
16. Sengelov H, Kjeldsen L, Borregaard N. Control of exocytosis in early neutrophil activation. J Immunol 1993; 150: 1535-43.
17. Schmidt HHHW, Walter U. NO at work. Cell 1994; 78: 919-25.
18. Marshall CJ. Specificity of receptor tyrosine kinase signalling: transient versus sustained extracellular signal-regulated kinase action. Cell 1995; 80: 179-85.
19. English D, Andersen BR. Single-step separation of red blood cells, granulocytes and mononuclear leukocytes on discontinuous density gradient of Ficoll-Hypaque. J Immunol Methods 1974; 5: 249-57.
20. Spertini O, Luscinskas FW, Munro JM, et al. Leukocytes adhesion molecule (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion and transmigration. J Immunol 1991; 147: 2565-73.
21. Spertini O, Luscinskas FW, Gimbrone MA, Tedder TF. Monocyte attachment to activated human vascular endothelium in vitro is mediated by leukocyte adhesion molecule-1 (L-selectin) under non-static conditions. J Exp Med 1992; 175: 1789-92.
22. Tsien RY, Poenie M. Fluorescence ratio imaging: a new window into intracellular ionic signalling. Trends Biochem Sci 1986; 11: 450-5.
23. Merritt JE, Jacob R, Hallam TJ. Use of manganese to discriminate between calcium influx and mobilization from internal stores in stimulated human neutrophils. J Biol Chem 1989; 264: 1522-7.
24. Fiorucci S, Santucci L, Gresele P, Luinetti O, Morelli A. Effect of NSAIDs on pepsinogen secretion and calcium mobilization in isolated chief cells. Am J Physiol 1995; 268: G968-78.
25. Santucci L, Fiorucci S, Giansanti M, et al. Pentoxyfilline prevents indomethacin-induced acute gastric mucosal damage in rats: role of tumor necrosis factor alpha. Gut 1994; 35: 909-15.
26. - oxidase containing particles from human neutrophils. Methods Enzymol 1984; 105: 358-60.
27. Pelicci G, Lanfrancone L, Grignani F, et al. A novel transforming protein (SHC) with an SH2 domain is implicated in mitogen signal trasduction. Cell 1992; 70: 93-104.
28. Fiorucci S, Distrutti E, Santucci L, Morelli A. Leukotrienes stimulate pepsinogen secretion from guinea pig gastric chief cells by a nitric oxide-dependent pathway. Gastroenterology 1995; 108: 1709-19.
29. Fiorucci S, Distrutti E, Chiorean M, et al. Nitric oxide modulates pepsinogen secretion induced by calcium-mediated agonist in guinea pig gastric chief cells. Gastroenterology 1995; 109: 1214-23.
30. Gukovskaya A, Pandol S. Nitric oxide production regulates cGMP formation and calcium influx in pancreatic acinar cells. Am J Physiol 1994; 266: G350-6.
31. Colton, T. Statistics in Medicine. Boston, MA: Little Brown and Co., 1978.
32. Asako H, Kubes P, Wallace J, Caginella T, Wolf RE, Granger DN. Indomethacin-induced leukocyte adhesion in mesenteric venules: role of lipoxygenase products. Am J Physiol 1992; 282: G903-8.
33. Flescher E, Fossum D, Gray PJ, et al. Aspirin-like drugs prime human T cells. Modulation of intracellular calcium concentrations. J Immunol 1991; 146: 2553-9.
34. Abramson SB, Cherksey B, Gude D, et al. Nonsteroidal antiinflammatory drugs exert differential effects on neutrophil function and plasma membrane viscosity. Studies in human neutrophils and liposomes. Inflammation 1990; 14: 11-20.
35. Trail KN, Ratheiser K, Pfeilshifter K, Wick G. Lymphocyte membrane lipid composition and mitogen responsiveness in chickens: role of membrane 'fluidity'. Eur J Immunol 1986; 16: 75-80.
36. Berridge MJ. Inositol trisphosphate and calcium signalling. Nature 1993; 361: 315-25.
37. 2α and thromboxane mimetic U-46619 on rat submucosal microcirculation in vivo. Am J Physiol 1985; 248: G580-6.
38. Dahlén SE, Björk J, Hedquist P, et al. Leukotrienes promote plasma leakage and leukocyte adhesion in post-capillary venules: in vivo effects with relevance to the acute inflammatory response. Proc Natl Acad Sci USA 1981; 78: 3887-91.
39. 4 production. Cell 1992; 69: 295-303.
40. Sengeløw H, Kjeldsen L, Diamond MS, Springer TA, Borregaard N. Subcellular localization and dynamic of MAC-1 (AmB2) in human neutrophils. J Clin Invest 1993; 92: 1467-76.
41. Lew DP, Monod A, Waldvogel FA, et al. Quantitative analysis of the cytosolic free calcium dependency of exocytosis from three subcellular compartments in intact human neutrophils. J Cell Biol 1986; 102: 2197-2204.
42. Sengeløv H, Kjeldsen L, Borregaard N. Control of exocytosis in early neutrophil activation. J Immunol 1993; 150: 1553-43.
43. Lew UP. Receptor signalling and intracellular calcium in neutrophil activation. Eur J Clin Invest 1989; 19: 338-46.
44. Lorant DE, McEver RP, McIntyre TM, et al. Activation of polymorphonuclear leukocytes reduces their adhesion to P-selectin and causes redistribution of ligands for P-selectin on their surfaces. J Clin Invest 1995; 96: 171-82.
45. Wyatt TA, Lincoln TM, Pryzwansky KB. Regulation of human neutrophil degranulation by LY-85585 and L-arginine: role of cGMP-dependent protein kinase. Am J Physiol 1993; 265: C201-11.
46. Kopp E, Ghosh S. Inhibition of NF-KB by sodium salicylate and aspirin. Science 1994; 265: 956-8.
47. Pawson T. Protein modules and signalling networks. Nature 1995; 373: 573-80.
48. Hunter T. Protein kinases and phosphalases: the yin and yang of protein phosphorylation and signalling. Cell 1995; 80: 225-36.
49. Durieu-Trautmann O, Chaverot N, Cazaubon S, Strosberg AD, Couraud PO. Intercellular adhesion molecule 1 activation induces tyrosine phosphorylation of the cytoskeleton-associated protein contractin in brain microvessel endothelial cells. J Biol Chem 1994; 17: 12 536-40.
50. Fuortes M, Jin W-W, Nathan C, Adhesion dependent protein tyrosine phosphorylation in neutrophils treated with tumor necrosis factor. J Cell Biol 1993; 120: 777-84.
51. 2 is phosphorylated and activated by MAP kinase. Cell 1993; 72: 269-78.
52. Lane TA, Lamkin GE, Wancewicz EV. Protein kinase C inhibitors block the enhanced expression of intracellular adhesion molecule-1 on endothelial cells activated by interleukin-1, lipolysaccharide and tumor necrosis factor. Biochem Biophys Res Commun 1990; 172: 1209-16.
53. Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991; 43: 109-42.
54. Bredt DS, Snyder SH. Isolation of nitric oxide synthase: a calmodulin-requiring enzyme. Proc Natl Acad Sci USA 1990; 87: 682-5.
55. Van Dervort AL, Yan L, Madara PJ, et al. Nitric oxide regulates endotoxin-induced TNF production by human neutrophils. J Immunol 1994; 152: 4102-9.
56. Geiger J, Nolte C, Walter U. Regulation of calcium mobilization and entry in human platelets by endothelium-derived factors. Am J Physiol 1994; 267: C236-44.
57. Gaboury J, Woodman R, Granger DN, Reinhardt P, Kubes P. Nitric oxide prevents leukocyte adherence: role of superoxide. Am J Physiol 1993; 265: H862-7.
58. Salvemini D, Manning PT, Zweifel S, et al. Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors. J Clin Invest 1995; 96: 301-8.
59. Kubes P, Suzuki M, Granger DN. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA 1991; 88: 4651-5.