Transgenic rabbit models for the study of atherosclerosis

Annals of the New York Academy of Sciences

Volumn 811, Issue , 1997, Pages 146-154

  Taylor, John M ^a  

^a GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; APOLIPOPROTEIN E; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN; LIPID; LIVER TRIACYLGLYCEROL LIPASE; LOW DENSITY LIPOPROTEIN RECEPTOR; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ATHEROSCLEROSIS; CHOLESTEROL BLOOD LEVEL; CONFERENCE PAPER; GENE EXPRESSION; IMMUNOCYTOCHEMISTRY; LIPID METABOLISM; LIPOPROTEIN BLOOD LEVEL; NONHUMAN; RABBIT; RECEPTOR BINDING; TRANSGENE;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0030791046     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1997.tb51997.x     Document Type: Conference Paper

References (23)

1. DUFF, G. L. 1935. Experimental cholesterol arteriosclerosis and its relationship to human arteriosclerosis. Arch. Pathol. 20: 81-123, 259-304.
2. CLARKSON, T. B., N. D. M. LEHNER & B. C. BULLOCK. 1974. Specialized research applications: I. Arteriosclerosis research. In The Biology of the Laboratory Rabbit. S. H. Weisbroth, R. E. Flatt & A. L. Kraus, Eds.: 155-165. Academic Press. San Diego.
3. PAIGEN, B., B. Y. ISHIDA, J. VERSTUYFT, R. B. WINTERS & D. ALBEE. 1990. Atherosclerosis susceptibility differences among progenitors of recombinant inbred strains of mice. Arteriosclerosis 10: 316-323.
4. WARREN, R. J., D. L. EBERT, A. MITCHELL & P. J. BARTER. 1991. Rabbit hepatic lipase cDNA sequence: Low activity is associated with low messenger RNA levels. J. Lipid Res. 32: 1333-1339.
5. HAVEL, R. J., T. KITA, L. KOTITE, J. P. KANE, R. L. HAMILTON, J. L. GOLDSTEIN & M. S. BROWN. 1982. Concentration and composition of lipoproteins in blood plasma of the WHHL rabbit. An animal model of human familial hypercholesterolemia. Arteriosclerosis 2: 467-474.
6. LUSIS, A. J., B. A. TAYLOR, D. QUON, S. ZOLLMAN & R. C. LEBOEUF. 1987. Genetic factors controlling structure and expression of apolipoproteins B and E in mice. J. Biol. Chem. 262: 7594-7604.
7. MAHLEY, R. W., K. H. WEISGRABER, M. M. HUSSAIN, B. GREENMAN, M. FISHER, T. VOGEL & M. GORECKI. 1989. Intravenous infusion of apolipoprotein E accelerates clearance of plasma lipoproteins in rabbits. J. Clin. Invest. 83: 2125-2130.
8. YAMADA, N., H. SHIMANO, H. MOKUNO, S. ISHIBASHI, T. GOTOHDA, M. KAWAKAMI, Y. WATANABE, Y. AKANUMA, T. MURASE & F. TAKAKU. 1989. Increased clearance of plasma cholesterol after injection of apolipoprotein E into Watanabe heritable hyperlipidemic rabbits. Proc. Natl. Acad. Sci. USA 86: 665-669.
9. TALL, A. R. 1986. Plasma lipid transfer proteins. J. Lipid Res. 27: 361-367.
10. YAMANAKA, S., M. E. BALESTRA, L. D. FERRELL, J. FAN, K. S. ARNOLD, S. TAYLOR, J. M. TAYLOR & T. L. INNERARITY. 1995. Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals. Proc. Natl. Acad. Sci. USA 92: 8483-8487.
11. CHAPMAN, M. J. 1980. Animal lipoproteins: Chemistry, structure, and comparative aspects. J. Lipid Res. 21: 789-853.
12. FAN, J., J. WANG, A. BENSADOUN, S. J. LAUER, Q. DANG, R. W. MAHLEY & J. M. TAYLOR. 1994. Overexpression of hepatic lipase in transgenic rabbits leads to a marked reduction of plasma high density lipoproteins and intermediate density lipoproteins. Proc. Natl. Acad. Sci. USA 91: 8724-8728.
13. DALEY, S. J., E. E. HERDERICK, J. F. CORNHILL & K. A. ROGERS. 1994. Cholesterol-fed and casein-fed rabbit models of atherosclerosis. Part 1: Differing lesion area and volume despite equal plasma cholesterol levels. Arterioscler. Thromb. 14: 95-104.
14. SHORE, V. G., B. SHORE & R. G. HART. 1974. Changes in apolipoproteins and properties of rabbit very low density lipoproteins on induction of cholesteremia. Biochemistry 13: 1579-1585.
15. THOMPSON, K. H. & D. B. ZILVERSMIT. 1983. Plasma very low density lipoprotein (VLDL) in cholesterol-fed rabbits: Chylomicron remnants or liver lipoproteins? J. Nutr. 113: 2002-2010.
16. MACKINNON, A. M., J. SAVAGE, R. A. GIBSON & P. J. BARTER. 1985. Secretion of cholesteryl ester-enriched very low density lipoproteins by the liver of cholesterol-fed rabbits. Atherosclerosis 54: 145-155.
17. OLIVECRONA, T. & G. BENGTSSON-OLIVECRONA. 1990. Lipoprotein lipase and hepatic lipase. Curr. Opin. Lipidol. 1: 222-230.
18. ROTHBLAT, G. H., F. H. MAHLBERG, W. J. JOHNSON & M. C. PHILLIPS. 1992. Apolipoproteins, membrane cholesterol domains, and the regulation of cholesterol efflux. J. Lipid Res. 33: 1091-1097.
19. KADOWAKI, H., G. M. PATTON & S. J. ROBINS. 1992. Metabolism of high density lipoprotein lipids by the rat liver: Evidence for participation of hepatic lipase in the uptake of cholesteryl ester. J. Lipid Res. 33: 1689-1698.
20. JI, Z.-S., S. J. LAUER, S. FAZIO, A. BENSADOUN, J. M. TAYLOR & R. W. MAHLEY. 1994. Enhanced binding and uptake of remnant lipoproteins by hepatic lipase-secreting hepatoma cells in culture. J. Biol. Chem. 269: 13429-13436.
21. THUREN, T., R. W. WILCOX, P. SISSON & M. WAITE. 1991. Hepatic lipase hydrolysis of lipid monolayers. Regulation by apolipoproteins. J. Biol. Chem. 266: 4853-4861.
22. SIMONET, W. S., N. BUCAY, S. J. LAUER & J. M. TAYLOR. 1993. A far-downstream hepatocyte-specific control region directs expression of the linked human apolipoprotein E and C-I genes in transgenic mice. J. Biol. Chem. 268: 8221-8229.
23. HUETTINGER, M., W. J. SCHNEIDER, Y. K. HO, J. L. GOLDSTEIN & M. S. BROWN. 1984. Use of monoclonal anti-receptor antibodies to probe the expression of the low density lipoprotein receptor in tissues of normal and Watanabe Heritable Hyperlipidemic rabbits. J. Clin. Invest. 74: 1017-1026.