Epidemiology of the gastroduodenal damage induced by aspirin and other non-steroidal anti-inflammatory drugs;Epidemiologia del danno gastroduodenale indotto dall'aspirina e dagli altri farmaci antiinfiammatori non steroidei

Recenti Progressi in Medicina

Volumn 88, Issue 5, 1997, Pages

  Dobrilla, Giorgio ^a   Benvenuti, Stefano ^a   De Guelmi, Alberto ^a  

^a OSPEDALE CA FONCELLO   (Italy)

Author keywords

Aspirin; Gastropathy; Non steroidal anti infiammatory drugs

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; AZAPROPAZONE; DICLOFENAC; DIFLUNISAL; IBUPROFEN; INDOMETACIN; KETOPROFEN; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; OXYPHENBUTAZONE; PIROXICAM; PLACEBO; STEROID; SULINDAC;

CLINICAL TRIAL; DUODENUM ULCER; GASTRODUODENAL ULCER; GASTROINTESTINAL HEMORRHAGE; HIGH RISK POPULATION; HUMAN; META ANALYSIS; PREVALENCE; REVIEW; STOMACH ULCER;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; DUODENAL ULCER; DUODENUM; GASTRIC MUCOSA; HUMANS; INTESTINAL MUCOSA; RISK FACTORS; STOMACH ULCER;

EID: 0030790694     PISSN: 00341193     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (78)

1. Soll AH, Weinstein WM, Kurata J, McCarthy D. Non-steroidal antiinflammatory drugs and peptic ulcer disease. Ann Intern Med 1991; 114: 307-19.
2. Graham DY, Smith JL, Spjut HJ, Torres E. Gastric adaptation. Studies in humans during continuous aspirin administration. Gastroenterology 1988b; 95: 327-33.
3. Griffin MR, Piper JM, Daugherty JR, Snowden M, Ray WA. Non-steroidal anti-inflammatory drugs use and increased risk for peptic ulcer disease in elderly persons. Ann Intern Med 1991; 114: 257-63.
4. Sommerville K, Faulkner G, Langman MJS. Non-steroidal anti-inflammatory drugs and bleeding peptic ulcer. Lancet 1986; 1: 462-4.
5. Armstrong CP, Blower AL. Non-steroidal antiinflammatory drugs and life threatening complications of peptic ulceration. Gut 1987; 28: 527-32.
6. Holvoet J, Terriere L, Van Hee W, Verbist L, Fierens E. et al. Relation of upper gastrointestinal bleeding to non-steroidal anti-inflammatory drugs and aspirin: a case-control study. Gut 1991; 32: 730-4.
7. Beardon PHG, Brown SV, MCDevitt DG. Gastrointestinal events in patients described non-steroidal anti-inflammatory drugs: a controlled study using record linkage in Tayside. Q J Med 1989; 71: 497-505.
8. Langman MJS. Epidemiologic evidence on the association between peptic ulceration and antinflammatory drug use. Gastroenterology 1989; 96: 640-6.
9. Del Favero A. Antiinflammatory analgesics and drugs used in rheumatoid arthritis and gout. In: Side effects of Drugs. Dukes MNG (Ed.), Amsterdam: Elsevier Science Publishers B.V. 1990; 14: 79.
10. Langman MJS. The assessment of evidence associating non-steroidal-antiinflammatory drugs with complications of peptic ulcerations. Can J Gastroenterology 1990; 4: 91.
11. Hawkey CJ. Non-steroidal anti-inflammatory drugs and peptic ulcers. Br Med J 1990; 300: 278.
12. Freis JF. Identification of patients at risk for gastropathy associated with NSAID use. J Rheum 1990; 17 (S20): 12.
13. Hudson N, Hawkey CJ. Non-steroidal antiinflammatory drug-associated upper gastrointestinal ulceration and complications. Eur J Gastroenterol Hepatol 1993; 5: 412-9.
14. Rees V, Carson JL, Strom BL. Epidemiology of gastrointestinal damage associated with non-steroidal anti-inflammatory drugs. Pharmacoepidemiology 1994; 10: 170-81.
15. Del Favero A. Lesioni gastroduodenali da FANS. In: Dobrilla G, de Pretis G, Comberlato M eds: Patologia gastrointestinale. Recenti acquisizioni terapeutiche. Verona: BiGi 1992, 11-9.
16. McCarthy. Nonsteroidal anti-inflammatory drugs-the clinical dilemmas. Scand J Gastroenterol 1992; 27 Suppl 192: 9-16.
17. Butt JH, Barthel JS, Moore RA. Clinical spectrum of the upper gastrointestinal effects of nonsteroidal anti-inflammatory drugs. Am J Med 1988; 84 Suppl 2A: 5-14.
18. Larkai EN, Smith L, Sessoms SL, Graham DY. Dyspepsia in NSAID users: the size of the problem. J Clin Gastroenterol 1989; 11: 158-62.
19. Bjilsma JWJ, Multicenter Group. Treatment of endoscopy - negative NSAID - induced upper gastrointestinal symptoms with cimetidine. An international multicenter collaborative study. Aliment Pharmacol Ther 1988; 2S: 75: 83.
20. Caruso I, Bianchi Porro G. Gastroscopic evaluation of anti-infammatory agents. Br Med J 1980; 1: 75-7.
21. Dobrilla G. Lo studio di coorte. In: Genazzani E, Labo G, Eandi M, Recchia G (eds.): 1987. Ranitidine. Farmacologia in gastroenterologia. Verona: Cortina International 1987; 23-32.
22. Persantine-Aspirin Reinfarction Study Research Group. Persantine and aspirin in coronary heart disease. Circulation 1980; 62: 449-61.
23. Cairns JA, Gent M, Singer J, Finnie KJ, Forggatt GM, et al. Aspirin, sulfinpyrazone, or both in unstable angina. N Engl J Med 1985; 313: 1369-75.
24. UK-TIA Study Group. United Kingdom transient ischaemic attack (UK-TIA) aspirin trial interim results. Br Med J 1988; 296: 316-20.
25. Steering Committee of the Physicians' Health Study Research Group. Final report on the aspirin component of the ongoing Physicians' Health Study. N Engl J Med 1989; 321:129-35.
26. Kurata JH, Abbey DE. The effect of chronic aspirin use on duodenal and gastric ulcer hospitalizations. J Clin Gastroenterol 1990; 12: 260-6.
27. SALT Collaborative Group. Swedish Aspirin Low-dose Trial (SALT) of 75 mg aspirin as secondary prophylaxis after cerebro-vascular ischaemic events. Lancet 1991; 338: 1345-9.
28. Juul-Moller S, Edvardsson N, Jahnmatz B, Rosen A, Sorensen S, et al. Double-blind trial of aspirin in primary prevention of myocardial infarction in patients with stable chronic angina pectoris. Lancet 1992; 340: 1421-5.
29. Levy M. Aspirin use in patients with major upper gastrointestinal bleeding and peptic-ulcer disease. N Engl J Med 1974; 290: 1158-62.
30. Piper DW, McIntosh JH, Ariotti DE, Fenton BH, MacLennan R. Analgesic ingestion and chronic peptic ulcer. Gastroenterology 1981; 80: 427-32.
31. Coggon D, Langman MJS, Spiegelhalter D. Aspirin,paracetamol, and haematemesis and melena. Gut 1982; 23: 340-4.
32. McIntosh JH, Byth K, Piper DW. Environmental factors in aetiology of chronic gastric ulcer: a case control study of exposure variables before the first symptoms. Gut 1985; 26: 789-8.
33. Faulkner G, Prichard P, Somerville K, Langman MJS. Aspirin and bleeding peptic ulcers in the elderly. Br Med J 1988; 297: 1311-3.
34. Levy M, Miller DR, Kaufman DW, Siskind V, Schwingl P, et al. Major upper gastrointesinal tract bleeding. Relation to the use of aspirin and other nonnarcotic analgesics. Arch Intern Med 1988; 148: 281-5.
35. Laporte JR, Carne X, Vidal X, Moreno V, Juan J. Upper gastrointestinal bleeding in relation to previous use of analgesics and nonsteroidal anti-inflammatory drugs. Lancet 1991; 337: 85-9.
36. Lanas A, Sekar MC, Hirschowitz BI. Objective evidence of aspirin use in both ulcer and nonulcer upper and lower gastrointestinal bleeding. Gastroenterology 1992; 103: 862-9.
37. Kaufman DW, Kelley JP, Sheehan JE, Laszlo A, Wiholm BE, et al. Non-steroidal anti-inflammatory drug use in relation to major upper gastrointestinal bleeding. Clinical Pharmacol Ther 1993; 53: 485-94.
38. Savage RL, Moller PW, Ballantyne CL, Wells JE. Variation in the risk of peptic ulcer complications with nonsteroidal antiinflammatory drug therapy. Arthritis and Rheumatism 1993; 36: 84-90.
39. Henry DA, Johnston A, Dobson A, Duggan J. Fatal peptic ulcer complications and the use of non-steroidal anti-inflammatory drugs, aspirin, and corticosteroids. Br Med J 1987; 295: 1227-9.
40. Bartle WR, Guupta AK, Lazor J. Nonsteroidal antiinflammatory drugs and gastrointestinal bleeding. A case-control study. Arch Intern Med 1986; 146: 2365-7.
41. Duggan JM, Dobson AJ, Johnson H, Fahey P. Peptic ulcer and non-steroidal anti-inflammatory agents. Gut 1986; 27: 929-33.
42. Griffin MR, Piper JM, Daugherty JR, Snowden M, Ray WA. Non-steroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons. Ann Intern Med 1991; 114: 257-63.
43. Beard K, Walker AM, Perera DR, Jick H. Nonsteroidal anti-inflammatory drugs and hospitalization for gastroesophageal bleeding in the elderly. Arch Intern Med 1987; 147: 1621-3.
44. Carson JL, Strom BL, Morse ML, West SL, Soper KA et al. The relative gastrointestinal toxicity of the non-steroidal antiinflammatory drugs. Arch Intern Med 1987a; 147: 1054-9.
45. Jick SS, Perera DR, Walker AM, Jick H. Non-steroidal anti-inflammatory drugs and hospital admission for perforated peptic ulcer. Lancet 1987; 2: 380-2.
46. Fries JF, Miller SR, Spitz PW, Williams CA, Hubert HB, et al. Toward an epidemiology of gastropathy associated with nonsteroidal anti-inflammatory drug use. Gastroenterology 1989; 96: 647-55.
47. Farah D, Sturrock RD, Russell RI. Peptic ulcer in rheumatoid arthritis. Am Rheum Dis 1988; 47: 478-80.
48. Silvoso GR, Ivek KJ, Butt JH, Lockhard OO, Holt SD, Sisk C, et al. Incidence of gastric lesions in patients with rheumatic disease on chronic aspirin therapy. Ann Intern Med 1979, 91: 517-20.
49. Morris AD, Hold SD, Silvoso GR, Hewitt J, Tatum W, Grandione J, et al. Effect of anti-inflammatory drug administration in patients with rheumatoid arthritis. Scand J Gastroenterol 1981, 16 (Suppl 67): 131-5.
50. Lockhard O, Ivek KJ, Butt JH, Silvoso GR, Sisk K, Holt S. The prevalence of duodenal lesions in patients with rheumatic diseases on chronic aspirin therapy. Gastrointest Endosc 1980; 26: 5-6.
51. Collins AJ, Du Torr JA. Upper gastrointestinal findings and faecal occult blood in patients with rheumatic diseases taking non-steroidal antiinflammatory drugs. Br J Rheumatol 1987; 26: 295-8.
52. Larkai EN, Smith IJ, Lidsky MD, Graham DY. Gastroduodenal mucosa and dyspeptic symptoms in arthritic patients during chronic non-steroidal antiinflammatory drug use. Am J Gastroenterol 1987; 82: 1153-8.
53. Yeomans ND, Elliot SL, Edwards J, Buchman R, Sturrock SD, Smallwood R. Gastroduodenal damage during therapy with non-steroidal antiinflammatory drugs (abstract). Gastroenterology 1988; 94: A510.
54. Biewer W, Buschmeier B, Bolten W. Risk factors of gastrointestinal injury: prospective multicentre study of 497 rheumatic patients (abstract). Gut 1990; 31: A1176.
55. Geis S, Stead H, Wallemark CB, Nicholson PA. Prevalence of mucosal lesions in the stomach and duodenum due to chronic use of NSAID in patients with rheumatoid arthritis or osteoarthritis, and interim report on prevention by misoprostol of diclofenac associated lesions. J Rheumatol 1991; 18 (Suppl. 28): 11-4.
56. Bernersen B, Johnsen R, Straume B, Burhol PG, Jenssent T, Stakkevold PA. Towards a true prevalence of peptic ulcer: the Sorreisa gastrointestinal disorder study. Gut 1990; 31: 989-92.
57. Watkinson G. The incidence of chronic peptic ulcer found at necropsy: a study of 20000 examinations performed in Leeds in 1930-49 and in England and Scotland in 1956. Gut 1956; 1: 14-30.
58. Committee on safety of medicines. Non-steroidal antiinflammatory drugs and serious gastrointestinal adverse reactions. Br Med J 1986; 292: 1190-1.
59. Garcia Rodriguez LA, Jick H. Risk of upper gastrointestinal blleding and perforations associated with individual non-steroidal antiinflammatory drugs. Lancet 1994; 343: 769-72.
60. Langman MJS, Weil J, Wainwright P, Lowson DH, Rawlins MD, Logan RFA, Murphy M, Vessey MP, Colin Jones DG. Risk of bleeding peptic ulcer associated with individual non-steroidal antiinflammatory drugs. Lancet 1994; 343: 1075-8.
61. Bateman DN. NSAIDs: time to re-evaluate gut toxicity. Lancet 1994; 343: 1051-2.
62. Quader K, Logan FA. Peptic ulcer death: how many occur at home or after non-steroidal antiinflammatory drugs prescribing. Gut 1988; 29: A1443.
63. Guess HA, West R, Strand LM, Helston D, Lydick EG. Fatal upper gastrointestinal hemorrhage or perforation among users and non-users of non-steroidal antiinflammatory drugs in Saskatchewan, Canada. J Clin Gastroenterol 1988; 41: 35-45.
64. Kelly JP, Kaufman A, Jurgelon JM. et al. Risk of aspirin-associated major upper-gastrointestinal bleeding with enteric-coated or buffered product. Lancet 1996; 348: 1413-6.
65. Weil J, Colin Jones D, Langman MJS et al. Prophylactic aspirin and the risk of peptic ulcer bleeding. Br Med J 1995; 310: 827-30.
66. Roderick PJ, Wilkes HC, Meade TW. Gastrointestinal toxicity of aspirin: an overview of randomized controlled trials. Br J Clin Pharmacol 1993; 35: 241-9.
67. Kurata JH, Abbey DE. The effect of chronic aspirin use on duodenal and gastric ulcer hospitalisations. J Clin Gastroenterol 1990; 12: 260-6.
68. Gabriel SE, Jaakkimainen S, Bombardier C. Risk of serious complications related to use of non-steroidal anti-inflammatory drugs. A meta-analysis. Ann Intern Med 1991; 115: 787-96.
69. Allison MC, Howarson AC, Torrance CJ, Lee FD, Russell RI. Gastrointestinal damage associated with the use of non-steroidal antiinflammatory drugs. N Engl J Med 1996; 327: 749-54.
70. Piper JM, Ray WA, Daugherty JR, Griffin MR. Corticosteroid use and peptic ulcer disease: role of non-steroidal anti-inflammatory drug. Ann Intern Med 1991; 114: 735-40.
71. FDA Drug Bulletin 1989 (February); 19: 3-4.
72. Smalley WE, Griffin MR, Daugherty JR. Hospitalization for ulcer-related diseases in the elderly Medicaid population. Gastroenterology 1992; 102: A25.
73. Fries JF, Williams CA, Bloch DA, Michel BA. Non-steroidal anti-inflammatory drug-associated gastropathy: incidence and risk factor models. Am J Med 1991; 91: 213-22.
74. Somerville K, Faulkner G, Langman MJS. Nonsteroidal anti-inflammatory drugs and bleeding peptic ulcer. Lancet 1986; 1: 462-4.
75. Walt R, Katchinski B, Logan R, Ashley J, Langman MJS. Rising frequency of peptic ulcer perforation in elderly people in the United Kingdom. Lancet 1986; 1: 489-92.
76. Shorr RI, Ray WA, Daugherty JR, Griffin MR. Concurrent use of nonsteroidal antiinflammatory drugs and oral anticoagulants places elderly persons at high risk for haemorrhagic peptic ulcer disease. Arch Intern Med 1993; 153: 1665-7.
77. Guslandi M. Epidemiological aspects of NSAID gastropathy. It J Gastroenterol 1996 (285); 4: 6-8.
78. La Corte R, Bajocchi G, Scagliarini R, Pazzi P, Trotta F. Relazione tra assunzione di FANS e malattia ulcerosa. In: Gullini S, Pazzi P eds: Ulcera peptica: dalla epidemiologia alla terapia. Mosby Doyma 1996: 61-8.