Primary structure and developmental acidic to basic transition of 13 alternatively spliced mouse fast skeletal muscle troponin T isoforms

Gene

Volumn 193, Issue 1, 1997, Pages 105-114

  Wang, Jennifer ^a,b   Jin, Jian Ping ^a,b  

^a UNIVERSITY OF CALGARY   (Canada)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cDNA cloning; Gene expression; mRNA processing; Nucleotide sequences; Postnatal development

Indexed keywords

ACID PROTEIN; BASIC PROTEIN; COMPLEMENTARY DNA; MESSENGER RNA; TROPONIN T;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EMBRYO; ESCHERICHIA COLI; EXON; FAST MUSCLE FIBER; GENE FREQUENCY; GENE STRUCTURE; MOLECULAR CLONING; MOUSE; MUSCLE DEVELOPMENT; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ISOLATION; SKELETAL MUSCLE;

ACIDS; AGE FACTORS; ALKALIES; ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; ANIMALS, NEWBORN; CLONING, MOLECULAR; DNA, COMPLEMENTARY; EXONS; MICE; MOLECULAR SEQUENCE DATA; MUSCLE FIBERS, FAST-TWITCH; MUSCLE, SKELETAL; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; TROPONIN; TROPONIN T;

ANIMALIA; ESCHERICHIA COLI;

EID: 0030790453     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(97)00100-5     Document Type: Article

References (49)

1. 2+ sensitivity of skinned cardiac muscle contractility coincident with troponin T band shifts in the diabetic rat. Circ. Res. 76, 600-606.
2. Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Smith, J.A., Seidman, J.G., Struhl, K. (Eds.), 1995. Current Protocols in Molecular Biology. Greene Publishing Associates and Wiley Interscience, New York.
3. Breitbart, R.E., Nadal-Ginard, B., 1986. Complete nucleotide sequence of the fast skeletal troponin T gene: alternatively spliced exons inhibit unusual interspecies divergence. J. Mol. Biol. 188, 313-324.
4. Briggs, M.M., Schachat, F., 1993. Origin of fetal troponin T: developmentally regulated splicing of a new exon in the fast troponin T gene. Dev. Biol. 158, 503-509.
5. Briggs, M.M., Schachat, F., 1996. Physiologically regulated alternative splicing patterns of fast troponin T RNA are conserved in mammals. Am. J. Physiol. 270 (Cell Physiol. 39), C298-C305.
6. Briggs, M.M., Maready, M., Schmidt, J.M., Schachat, F., 1994. Identification of a fetal exon in the human fast troponin T gene. FEBS Lett. 350, 37-40.
7. Brisson, J.R., Golosinska, K., Smillie, L.B., Sykes, B.D., 1986. Interaction of tropomyosin and troponin T: a proton nuclear magnetic resonance study. Biochemistry 25, 4548-4555.
8. Bucher, E.A., de la Brousse, F.C., Emerson Jr., C.P., 1989. Developmental and muscle specific regulation of avian fast skeletal troponin T isoform expression by mRNA splicing. J. Biol. Chem. 264, 12482-12491.
9. Cooper, T.A., Ordahl, C.P., 1985. A single cardiac troponin T gene generates embryonic and adult isoforms via developmentally regulated alternative splicing. J. Biol. Chem. 260, 11140-11148.
10. Fisher, D., Wang, G., Tobacman, L.S., 1995. NH2-terminal truncation of skeletal muscle troponin T does not alter the Ca2+ sensitivity of thin filament assembly. J. Biol. Chem. 270, 25455-25460.
11. Fujita, S., Maéda, K., Maéda, Y., 1991. Complete coding sequences of cDNAs of four variants of rabbit skeletal muscle troponin T. J. Muscle Res. Cell Motil. 12, 560-565.
12. Fujita, S., Maéda, K., Maéda, Y., 1992. Expression in E. coli and a functional study of a β-troponin T 25 kDa fragment of rabbit skeletal muscle. J. Biochem. 112, 306-308.
13. Fyrberg, E., Fyrberg, C.C., Beall, C., Saville, D.L., 1990. Drosophila melanogaster troponin-T mutations engender three distinct syndromes of myofibrillar abnormalities. J. Mol. Biol. 216, 657-675.
14. Gahlmann, R., Troutt, A.B., Wade, R.P., Gunning, P., Kedes, L., 1987. Alternative splicing generates variants in important functional domains of human slow skeletal troponin T. J. Biol. Chem. 262, 16122-16126.
15. Gao, J., Hwang, J.M., Jin, J.-P., 1996. Complete nucleotide sequence, structural organization and an alternatively spliced exon of mouse h1-calponin gene. Biochem. Biophys. Res. Commun. 218, 292-297.
16. Greig, A., Hirschberg, Y., Anderson, P.A.W., Hainsworth, C., Malouf, N.N., Oakeley, A.E., Kay, B.K., 1994. Molecular basis of cardiac troponin T isoform heterogeneity in rabbit heart. Circ. Res. 74, 41-47.
17. Gulati, J., Akella, A.B., Nikolic, S.D., Stare, V., Siri, F., 1994. Shifts in contractile regulatory protein subunits troponin T and troponin I in cardiac hypertrophy. Biochem. Biophys. Res. Commun. 202, 384-390.
18. Jin, J.-P., 1995. Cloned rat cardiac titin class I and class II motifs: expression, purification, characterization, and interaction with F-actin. J. Biol. Chem. 270, 6908-6916.
19. Jin, J.-P., Lin, J.J.-C., 1988. Rapid purification of mammalian cardiac troponin T and its isoform switching in rat hearts during development. J. Biol. Chem. 263, 7309-7315.
20. Jin, J.-P., Lin, J.J.-C., 1989. Isolation and characterization of cDNA clones encoding embryonic and adult isoforms of rat cardiac troponin T. J. Biol. Chem. 264, 14471-14477.
21. Jin, J.-P., Smillie, L.B., 1994. An unusual metal-binding cluster found exclusively in the avian breast muscle troponin T of Galliformes and Craciformes. FEBS Lett. 324, 135-140.
22. Jin, J.-P., Resek, M.E., 1996. Primary structure of mouse slow skeletal muscle troponin T and developmentally regulated expression. Mol. Cell. Biol. 7, 537a.
23. Jin, J.-P., Lin, J.L.-C., Lin, J.J.-C., 1990. Troponin T isoform switching during heart development. Ann. N.Y. Acad. Sci. 588, 393-396.
24. Jin, J.-P., Huang, Q.-Q., Yeh, H.-I, Lin, J.J.-C., 1992. Complete nucleotide sequence and structural organization of rat cardiac troponin T gene. A single gene generates embryonic and adult isoforms via developmentally regulated alternative splicing. J. Mol. Biol. 227, 1269-1276.
25. Jin, J.-P., Wang, J., Zhang, J., 1996. Expression of cDNAs encoding mouse cardiac troponin T isoforms: characterization of a large sample of independent clones. Gene 168, 217-221.
26. Leavis, P.C., Gergely, J., 1984. Thin filament proteins and thin filament-linked regulation of vertebrate muscle contraction. CRC Crit. Rev. Biochem. 16, 235-305.
27. Leszyk, J., Dumaswala, R., Potter, J.D., Gusev, N.B., Verin, A.D., Tobacman, L.S., Collins, J.H., 1987. Bovine cardiac troponin T: amino acid sequences of the two isoforms. Biochemistry 26, 7035-7042.
28. Mak, A.S., Smillie, L.B., 1981. Structural interpretation of the twosite binding of troponin on the muscle thin filament. J. Mol. Biol. 149, 541-550.
29. McAuliffe, J.J., Robbins, J., 1991. Troponin T expression in normal and pressure-loaded fetal sheep heart. Pediatric Res. 29, 580-585.
30. Morgan, M.J., Earnshaw, J.C., Dhoot, G.K., 1993. Novel developmentally regulated exon identified in the rat fast skeletal muscle troponin T gene. J. Cell Sci. 106, 903-908.
31. Myers, C.D., Goh, P.Y., Allen, T.S.C., Bucher, E.A., Bogaert, T., 1996. Developmental genetic analysis of troponin T mutations in striated and nonstriated muscle cells of Caenorhabditis elegans. J. Cell Biol. 132, 1061-1077.
32. 2-terminal variable region on the conformation of intact troponin T and its association with tropomyosin. Biochemistry 35, 16581-16590.
33. Pan, B.-S., Gordon, A.M., Potter, J.D., 1991. Deletion of the first 45 NH2-terminal residues of rabbit skeletal troponin T strengthens binding of troponin T to immobilized tropomyosin. J. Biol. Chem. 266, 12432-12438.
34. Pearlstone, J.R., Carpenter, M.R., Smillie, L.B., 1977. Primary structure of rabbit skeletal muscle troponin T. J. Biol. Chem. 252, 971-977.
35. Saba, Z., Nassar, R., Ungerleider, R.M., Oakeley, A.E., Anderson, P.A.W., 1996. Cardiac troponin T isoform expression correlates with pathophysiological descriptors in patients who underwent corrective surgery for congenital heart disease. Circulation 94, 472-476.
36. Sambrook, J., Fritsch, E.F., Maniatis, T. (Eds.), 1989. Molecular Cloning. A Laboratory Manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
37. Samson, F., Mesnard, L., Mihovilovic, M., Potter, T.G., Mercadier, J.-J., Roses, A.D., Gilbert, J.R., 1994. A new human slow skeletal troponin T (TnTs) mRNA isoform derived from alternative splicing of a single gene. Biochem. Biophys. Res. Commun. 199, 841-847.
38. Schachat, F., Schmidt, J.M., Maready, M., Briggs, M.M., 1995. Chicken perinatal troponin Ts are generated by a combination of novel and phylogenetically conserved alternative splicing pathways. Dev. Biol. 171, 233-239.
39. Schaertl, S., Lehrer, S.S., Geeves, M.A., 1995. Separation and characterization of the two functional regions of troponin involved in muscle thin filament regulation. Biochemistry 34, 15890-15894.
40. Short, J.M., Fernandez, J.M., Sorge, J.A., Huse W.D., 1988. λ ZAP: a bacterial λ expression vector with in vivo excision properties. Nucleic Acid Res. 16, 7583-7600.
41. Smillie, L.B., Golosinska, K., Reinach, F., 1988. Sequences of complete cDNAs encoding four variants of chicken skeletal muscle troponin T. J. Biol. Chem. 263, 18816-18820.
42. Tobacman, L.S., Lee, R., 1987. Isolation and functional comparison of bovine cardiac troponin T isoforms. J. Biol. Chem. 262, 4059-4064.
43. Townsend, P.J., Farza, H., MacGeoch, C., Spurr, N.K., Wade, R., Gahlmann, R., Yacoub, M.H., Barton P.J.R., 1994. Human cardiac troponin T: identification of fetal isoforms and assignment of the TNNT2 locus to chromosome 1q. Genomics 21, 311-316.
44. Townsend, P.J., Barton P.J.R., Farza, H., 1995. Molecular cloning of human cardiac troponin T isoforms: expression in developing and failing hearts. J. Mol. Cell. Cardiol., 2223-2236.
45. White, S.P., Cohen, C., Phillips Jr., G.N., 1987. Structure of co-crystals of tropomyosin and troponin. Nature 325, 826-828.
46. Wu, Q.-L., Jha, P.K., Raychowdhury, M.K., Du, Y., Leavis, P.C., Sarkar, S., 1994. Isolation and characterization of human fast skeletal β-troponin T cDNA: Comparative sequence analysis of isoforms and insight into the evolution of members of multigene family. DNA Cell Biol. 13, 217-233.
47. Wu, Q.-L., Jha, P.K., Raychowdhury, M.K., Du, Y., Leavis, P.C., Sarkar, S., 1995. Overproduction and rapid purification of human fast skeletal beta troponin T using E. coli expression vectors: functional differences between the alpha and beta forms. Gene 155, 225-230.
48. Yonemura, I., Watanabe, T., Kironoki, M., Miyazaki, J.-I., Hirabayashi, T., 1996. Cloning of chicken slow muscle troponin T and its sequence comparison with that of human. Biochem. Biophys. Res. Commun. 226, 200-205.
49. Zot, A.S., Potter, J.D., 1987. Structural aspects of troponin-tropomyosin regulation of muscle contraction. Annu. Rev. Biophys. Biophys. Chem. 16, 535-559.