Cyclopropanation/reduction of a 3,4-disubstituted 2(5H)-furanone: A model for C-8 methylation at the taxane BC ring juncture

Journal of Organic Chemistry

Volumn 62, Issue 15, 1997, Pages 5069-5073

  Janini, Thomas E ^a   Sampson, Paul ^a  

^a KENT STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 10 OXABICYCLO[6.3.0]UNDECAN 9 ONE; 10 OXA[6.3.1]PROPELLAN 9 ONE; 4,5,6,7,8,9 HEXAHYDROCYCLOOCTA[C]FURAN 1(3H) ONE; AMMONIA; CYCLOPROPANE; DEUTERIUM; DIMETHYL SULFOXIDE; FURANONE DERIVATIVE; LITHIUM; TAXANE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; METHYLATION; PROTON NUCLEAR MAGNETIC RESONANCE; REDUCTION; STEREOCHEMISTRY; TEMPERATURE;

EID: 0030790368     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo970564u     Document Type: Article

References (43)

1. Also called Taxol, a registered trademark of the Bristol-Myers Squibb Company.
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