Intrathecal neurokinin-1 receptor antagonist reduces isoflurane MAC in rats

Canadian Journal of Anaesthesia

Volumn 44, Issue 5, 1997, Pages 543-549

  Ishizaki, Keiji ^a   Karasawa, Syunji ^a   Takahashi, Kenichiro ^a   Hasegawa, Mamoru ^a   Goto, Fumio ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 BENZHYDRYL 3 (2 METHOXYBENZYLAMINO) 1 AZABICYCLO[2.2.2]OCTANE; ISOFLURANE; NEUROKININ 1 RECEPTOR ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG CONCENTRATION; DRUG EFFECT; GENERAL ANESTHESIA; INTRATHECAL DRUG ADMINISTRATION; LOCOMOTION; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; SPINAL CORD;

EID: 0030790325     PISSN: 0832610X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03011945     Document Type: Article

References (35)

1. Namiki A, Collins JG, Kitahata LM, Kikuchi H, Homma E, Thalhammer JG. Effects of halothane on spinal neuronal responses to graded noxious heat stimulation in the cat. Anesthesiology 1980; 53: 475-80.
2. Rampil IJ, Mason P, Singh H. Anesthetic potency (MAC) is independent of forebrain structures in the rat. Anesthesiology 1993; 78: 707-12.
3. Antognini JF, Schwartz K. Exaggerated anesthetic requirements in the preferentially anesthetized brain. Anesthesiology 1993; 79: 1244-9.
4. Ishizaki K, Yoon DM, Yoshida N, Yamazaki M, Arai K, Fujita T. Intrathecal administration of N-methyl-D-aspartate receptor antagonist reduces the minimum alveolar anaesthetic concentration of isoflurane in rats. Br J Anaesth 1995; 75: 636-8.
5. Ishizaki K, Yoshida N, Yoon DM, Yoon M-H, Sudoh M, Fujita T. Intrathecally administered NMDA receptor antagonists reduce the MAC of isoflurane in rats. Can J Anaesth 1996; 43: 724-30.
6. Go VLW, Yaksh TL. Release of substance P from the cat spinal cord. J Physiol (Lond) 1987; 391: 141-67.
7. Kuraishi Y, Hirota N, Sato Y, Hanashima H, Takagi H, Satoh M. Stimulus specificity of peripherally evoked substance P release from the rabbit dorsal horn in situ. Neuroscience 1989; 30: 241-50.
8. Heike CJ, Krause JE, Mantyh PW, Couture R, Bannon MJ. Diversity in mammalian tachykinin peptidergic neurons: multiple peptides, receptors, and regulatory mechanism. FASEB J 1990; 4: 1606-15.
9. Regoli D, Drapeau G, Dion S, D-Orléans-Juste P. Pharmacological receptors for substance P and neurokinins. Life Sci 1987; 40: 109-17.
10. Fleetwood-Walker SM, Mitchell R, Hope PJ, El-Yassir N, Molony V, Bladon CM. The involvement of neurokinin receptor subtypes in somatosensory processing in the superficial dorsal horn of the cat. Brain Res 1990; 519: 169-82.
11. Yasphal K, Dam T-V, Quirion R. Quantitative autoradiographic distribution of multiple neurokinin binding sites in the rat spinal cord. Brain Res 1990: 506: 259-66.
12. Hylden JLK, Wilcox GL. Intrathecal substance P elicits a caudally-directed biting and scratching behavior in mice. Brain Res 1981; 217: 212-5.
13. 1) receptor. Science 1991; 251: 435-7.
14. Yamamoto T, Taksh TL. Stereospecific effects of a non-peptidic NK1 selective antagonist, CP-96,345: antinociception in the absence of motor dysfunction. Life Sci 1991; 49: 1955-63.
15. Nagahisa A, Kanai Y, Suga O, et al. Antiinflammatory and analgesic activity of a non-peptide substance P receptor antagonist. Eur J Pharmacol 1992; 217: 191-5.
16. Taksh TL, Rudy TA. Chronic catheterization of spinal subarachnoid space. Physiol Behav 1976; 17: 1031-6.
17. Penning JP, Yaksh TL. Interaction of intrathecal morphine with bupivacaine and lidocaine in the rat. Anesthesiology 1992; 77: 1186-200.
18. Colquhoun AD, Gray WM, Asbury AJ. An evaluation of the Datex Normac anaesthetic agent monitor. Anaesthesia 1986; 41: 198-204.
19. Eger EI II, Saidman LJ, Brandstater B. Minimum alveolar anesthetic concentration: a standard of anesthetic potency. Anesthesiology 1965; 26: 756-63.
20. Coderre TJ, Van Empel I. The utility of excitatory amino acid (EAA) antagonists as analgesic agents. I. Comparison of the antinociceptive activity of various classes of EAA antagonists in mechanical, thermal and chemical nociceptive tests. Pain 1994; 59: 345-52.
21. 1) receptor antagonist. Science 1991; 251:437-9.
22. Asada H, Tamaguchi T, Tsunoda S, Fukuda Y. The role of spinal cord activation before neurectomy in the development of autotomy. Pain 1996; 64: 161-7.
23. Wang L, Sadoun E, Stephens RE, Ward PE. Metabolism of substance P and neurokinin A by human vascular endothelium and smooth muscle. Peptide 1994; 15: 497-503.
24. Quash AL, Eger EI II, Tinker JH. Determination and applications of MAC. Anesthesiology 1980; 53: 315-34.
25. Otsuka M, Konishi M. Electrophysiology of the mammalian spinal cord in vitro. Nature 1974; 252: 733-4.
26. Thompson SWN, Gerber G, Sivilotti LG, Woolf CJ. Long duration ventral root potentials in the neonatal rat spinal cord in vitro; the effects of ionotropic and metabotropic excitatory amino acid receptor antagonists. Brain Res 1992; 595: 87-97.
27. 2 receptor activation to high threshold afferent fibre evoked ventral root responses in the rat spinal cord in vitro. Brain Res 1993; 625: 100-8.
28. Aanonsen LM, Lei S, Wilcox GL. Excitatory amino acid receptors and nociceptive neurotransmission in rat spinal cord. Pain 1990; 41: 309-21.
29. Willcockson WS, Chung JM, Hori Y, Lee KH, Willis WD. Effects of iontophoretically released amino acids and amines on primate spinothalamic tract cells. J Neuroscience 1984; 4: 732-40.
30. Randi M, Heimovi H, Ryu PD. Substance P modulates glutamate-induced currents in acutely isolated rat spinal dorsal horn neurones. Neurosci Lett 1990; 117: 74-80.
31. Dougherty PM, Palecek J, Zorn S, Willis WD. Combined application of excitatory amino acids and substance P produces long-lasting changes in responses of primate spinothalamic tract neurons. Brain Res Rev 1993; 18: 227-46.
32. 2+ channels. Eur J Pharmacol 1992; 215: 351-2.
33. Nagahisa A, Asai R, Kanai Y, et al. Non-specific activity of (±) cp-96,345 in models of pain and inflammation. Regul Pept 1993; 46: 433-6.
34. 1 receptor antagonist L-733,060 in gerbils. Pain 1996; 67: 189-95.
35. 1 receptor antagonist, CP-99,994, in antinociceptive tests in rat, mouse and gerbil. Eur J Pharmacol 1994; 271: 481-7.