Search for new anticonvulsant compounds, part 2: Structure-activity relationship studies of new N-substituted amides of α-piperazine-γ- hydroxybutyric acid as active anticonvulsants

Archiv der Pharmazie

Volumn 330, Issue 4, 1997, Pages 91-99

  Malawska, Barbara ^a   Kulig, Katarzyna ^a   Ciechanowicz Rutkowska, Maria ^b  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

Amides of piperazine hydroxybutyric acid; Anticonvulsant activity; SAR; X ray structure determination

Indexed keywords

ALPHA (4 PHENYLPIPERAZINE) GAMMA HYDROXYBUTYRIC ACID; ANTICONVULSIVE AGENT; HYDROXYBUTYRIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PIPERAZINE; UNCLASSIFIED DRUG;

ANTICONVULSANT ACTIVITY; ARTICLE; CRYSTAL STRUCTURE; DRUG CONFORMATION; EPILEPSY; GABAERGIC TRANSMISSION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTICONVULSANTS; CONVULSANTS; CRYSTALLOGRAPHY, X-RAY; DRUG EVALUATION, PRECLINICAL; ELECTROSHOCK; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED STRAINS; MOLECULAR STRUCTURE; PENTYLENETETRAZOLE; PIPERAZINES; RATS; RATS, INBRED STRAINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030790189     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.19973300403     Document Type: Article

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