Peroxisome proliferators increase the formation of BPDE-DNA adducts in isolated rat hepatocytes

Toxicology

Volumn 122, Issue 1-2, 1997, Pages 81-91

  Voskoboinik, I ^a   Ooi, S G ^b   Drew, R ^c   Ahokas, J T ^a  

^a RMIT UNIVERSITY   (Australia)

^b CMS and F Environmental Engineers   (Australia)

^c ICI Australia Ltd   (Australia)

Author keywords

Benzo(a)pyrene 7,8 dihydrodiol 9,10 epoxide (BPDE); Cytochrome P450 (CYP); Di(2 ethylhexyl)phthalate (DEHP); Glutathione S transferase; Peroxisome proliferators; Silvex

Indexed keywords

7,8 DIHYDRO 7,8 DIHYDROXYBENZO[A]PYRENE; BENZO[A]PYRENE 7,8 DIHYDRODIOL 9,10 OXIDE; CARCINOGEN; CYTOCHROME P450; CYTOCHROME P450 ISOENZYME; DRUG METABOLIZING ENZYME; FENOPROP; GLUTATHIONE TRANSFERASE; HERBICIDE; MUTAGENIC AGENT; PEROXISOME PROLIFERATOR; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DETOXIFICATION; DNA ADDUCT; GLUTATHIONE METABOLISM; HYDROLYSIS; LIVER CELL; MALE; METABOLIC ACTIVATION; MITOSIS RATE; NONHUMAN; PEROXISOME; PRIORITY JOURNAL; RAT; XENOBIOTIC METABOLISM;

2,4,5-TRICHLOROPHENOXYACETIC ACID; 7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ANIMALS; CELL LINE; DIETHYLHEXYL PHTHALATE; DIHYDROXYDIHYDROBENZOPYRENES; DNA ADDUCTS; HERBICIDES; INDOLEACETIC ACIDS; LIVER; MALE; MICROBODIES; OXIDATION-REDUCTION; RATS; RATS, WISTAR;

ANIMALIA;

EID: 0030789865     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(97)00083-8     Document Type: Article

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