Effects of transforming growth factor β on the production of prostaglandin E and caseinase activity of unstimulated and interleukin 1-stimulated human articular chondrocytes in culture

British Journal of Rheumatology

Volumn 36, Issue 7, 1997, Pages 729-734

  Fawthrop, F W ^a,c   Frazer, A ^a   Russell, R G G ^a   Bunning, R A D ^b  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b SHEFFIELD HALLAM UNIVERSITY   (United Kingdom)

^c ROTHERHAM GENERAL HOSPITAL   (United Kingdom)

Author keywords

Caseinase activity; Chondrocytes; Interleukin 1; Prostaglandin E; Transforming growth factor

Indexed keywords

INTERLEUKIN 1; PROSTAGLANDIN E; PROTEINASE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2;

ADULT; AGED; ARTICLE; CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL CULTURE; CELL METABOLISM; CELL STIMULATION; CONNECTIVE TISSUE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TISSUE REPAIR;

AGED; AGED, 80 AND OVER; CARTILAGE, ARTICULAR; CELL DIVISION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; DRUG INTERACTIONS; EXTRACELLULAR MATRIX; HUMANS; INTERLEUKIN-1; METALLOENDOPEPTIDASES; MIDDLE AGED; PROSTAGLANDINS E; RADIOIMMUNOASSAY; TRANSFORMING GROWTH FACTOR BETA;

EID: 0030789442     PISSN: 02637103     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Sporn MB, Roberts AB, Wakefield LM, de Crombrugghe B. Some recent advances in the chemistry and biology of transforming growth factor beta. J Cell Biol 1987;105:1039-45.
2. Roberts AB, Sporn MB. The transforming growth factor βs. In: Sporn MB, Roberts AB, eds. Handbook of experimental pharmacology, peptide growth factors and their receptors I, Vol. 95. Heidelberg: Springer Verlag, 1990:419-72.
3. Okazaki R, Sakai A, Nakamura T, Kunugita N, Norimura T, Suzuki K. Effects of transforming growth factor βs and basic fibroblast growth factor on articular chondrocytes obtained from immobilised rabbit knees. Ann Rheum Dis 1996;55:181-6.
4. Sporn MB, Roberts AB. Transforming growth factor-β: multiple actions and potential clinical applications. J Am Med Assoc 1989;262:938-41.
5. Ignotz RA, Massague J. Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem 1986;264:4337-45.
6. Matrisian LM, Leroy P, Ruhlmann C, Gesnel M-C, Breathnach R. Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts. Mol Cell Biol 1986;6:1679-88.
7. Keski-Oja J, Blasi F, Leof EB, Moses HL. Regulation of the synthesis and activity in A549 human lung carcinoma cells by transforming growth factor-β. J Cell Biol 1988;106:451-9.
8. Laiho M, Saksela O, Andreasen PA, Keski-Oja J. Enhanced production and extracellular deposition of the endothelial type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor-beta. J Cell Biol 1986;103:2403-10.
9. Chandrasekhar S, Harvey AK. Transforming growth factor-β is a potent inhibitor of interleukin-1 induced protease activity and cartilage proteoglycan degradation. Biochem Biophys Res Commun 1988;157:1352-9.
10. Andrews HJ, Edwards TA, Cawston TE, Hazelman BL. Transforming growth factor-beta causes partial inhibition of interleukin-1-stimulated cartilage degradation in vitro. Biochem Biophys Res Commun 1989;162:144-50.
11. Morales TI, Joyce ME, Sobel ME, Danielpour D, Roberts AB. Transforming growth factor-beta in calf articular cartilage organ cultures: synthesis and distribution. Arch Biochem Biophys 1991;288:397-405.
12. Lafeber FPJG, Van der Kraan PM, Huber-Bruning O, Van den Berg WB, Bijlsma JWJ. Osteoarthritic human cartilage is more sensitive to transforming growth factor β than is normal cartilage. Br J Rheumatol 1993;32:281-6.
13. Vivien D, Galéra P, Lebrun E, Loyau G, Pujol J-P. Differential effects of transforming growth factor-β and epidermal growth factor on the cell cycle of cultured rabbit articular chondrocytes. J Cell Physiol 1990; 143:534-45.
14. 3H] thymidine incorporation by human articular chondrocytes in vitro. Biochim Biophys Acta 1994;1226:193-200.
15. Van Beuningen HM, Van der Kraan PM, Arntz OJ, Van den Berg WB. Protection from interleukin 1 induced destruction of articular cartilage by transforming growth factor β: studies in anatomically intact cartilage in vitro and in vivo. Ann Rheum Dis 1993;52:185-91.
16. Wood DD, Ihrie EJ, Dinarello CA, Cohen PL. Isolation of an interleukin-1-like factor from human joint effusions. Arthritis Rheum 1983;26:975-83.
17. Fava R, Olsen N, Keski-Oja J, Moses HL, Pincus T. Active and latent forms of transforming growth factor β activity in synovial effusions. J Exp Med 1989;169:291-6.
18. Lafyatis R, Thompson NL, Remmers EF et al. Transforming growth factor-β production by synovial tissues from rheumatoid patients and streptococcal cell wall arthritic rats. J Immunol 1989;143:1142-8.
19. Frazer A, Seid JM, Hart KA, Bentley H, Bunning RAD, Russell RGG. Detection of mRNA for the transforming growth factor β family in human articular chondrocytes by the polymerase chain reaction. Biochem Biophys Res Commun 1991;180:602-8.
20. Villiger PM, Kusari AB, ten Dijke P, Lotz M. IL-1β and IL-6 selectively induce transforming growth factor β isoforms in human articular chondrocytes. J Immunol 1993;151:44-50.
21. Cawston TE, Galloway WA, Mercer E, Murphy G, Reynolds JJ. Purification of rabbit bone inhibitor of collagenase. Biochem J 1981;195:159-65.
22. Vane JR. The mode of action of aspirin and similar compounds. J Allergy Clin Immunol 1976;58:690-712.
23. Raisz LG. The role of prostaglandins in the local regulation of bone metabolism. Prog Clin Biol Res 1990;332:195-203.
24. 2 production by recombinant human interleukin-1 and tumour necrosis factor. Biochim Biophys Acta 1990;1051:310-8.
25. Taylor DJ, Feldmann M, Evanson JM, Woolley DE. Comparative and combined effects of transforming growth factors α and β, interleukin 1 and interferon-gamma on rheumatoid synovial cell proliferation, glycolysis and prostaglandin E production. Rheumatol Int 1989;9:65-70.
26. Woessner JF. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J 1991;5:2145-54.
27. Murphy G, Cockett MI, Stephens PE, Smith BJ, Docherty AJP. Stromelysin is an activator of procollagenase. Biochem J 1987;248:265-8.
28. Martel-Pelletier J, Zafarullah M, Kodama S, Pelletier J-P. In vitro effects of interleukin 1 on the synthesis of metalloproteinases, TIMP, plasminogen activators and inhibitors in human articular cartilage. J Rheumatol 1991;18(suppl. 27):80-4.
29. Woessner J, Gunja-Smith Z. Role of metalloproteinases in human osteoarthritis. J Rheumatol 1991;18(suppl. 27):99-101.
30. Meats JE, Elford PR, Bunning RAD, Russell RGG. Retinoids and synovial factor(s) stimulate the production of plasminogen activator by cultured human chondrocytes: a possible role for plasminogen activator in the resorption of cartilage in vitro. Biochim Biophys Acta 1985;838:161-9.
31. Frazer A, Bunning RAD, Russell RGG. Modulation of human articular chondrocyte phenotype by transforming growth factor-β and interleukin-1β in vitro. Osteoarthritis Cartilage 1994;2:235-45.
32. Richardson JH, Elford PR, Sharrard RM, Meats JE, Russell RGG. Modulation of connective tissue metabolism by partially purified human interleukin 1. Cell Immunol 1985;90:41-51.
33. Bunning RAD, Russell RGG. The effect of tumour necrosis factor or on the resorption of human articular cartilage and on the production of prostaglandin E and of caseinase activity by human articular chondrocytes. Arthritis Rheum 1989;32:780-4.
34. Godfrey K. Statistics in practice: comparing the means of several groups. N Engl J Med 1988;313:1450-6.
35. Flanders KC, Thomson NL, Cissel DS et al. Transforming growth factor-β 1: histochemical localization with antibodies to different epitopes. J Cell Biol 1989;108:653-60.
36. Ellingsworth LR, Brennan JE, Fok K et al. Antibodies to the N-terminal portion of cartilage-inducing factor A and transforming growth factor β: immunohistochemical localization and association with differentiating cells. J Biol Chem 1986;261:12362-7.
37. Harvey AK, Hrubey PS, Chandrasekhar S. Transforming growth factor-beta inhibition of interleukin-1 activity involves down-regulation of interleukin-1 receptors on chondrocytes. Exp Cell Res 1991;195:376-85.
38. Rédini F, Mauviel A, Pronost S, Loyau G, Pujol J-P. Transforming growth factor β exerts opposite effects from interleukin-1β on cultured rabbit articular chondrocytes through reduction of interleukin-1 receptor expression. Arthritis Rheum 1993;36:44-50.
39. Smith RJ, Justen JM, Sam LM, Rohloff NA, Ruppel PL, Brunden MN et al. Platelet derived growth factor potentiates cellular responses of articular chondrocytes to interleukin-1. Arthritis Rheum 1991;34:697-706.
40. Bandara G, Lin CW, Georgescu HI, Evans CH. Chondrocyte activation by interleukin-1: synergism with fibroblast growth factor and phorbol myristate acetate. Agents Actions 1989;27:439-41.
41. Fawthrop FW, Russell RGG, Bunning RAD. The modulation of interleukin-1β-stimulated prostaglandin E production and caseinase activity by platelet derived growth factors AA, AB and BB in human articular chondrocytes. Calcif Tissue Int 1992;50(suppl.):A24.
42. Danielpour D, Sporn MB. Differential inhibition of transforming growth factor beta 1 and transforming growth factor beta 2 activity by alpha 2-macroglobulin. J Biochem 1990;265:6973-7.
43. Goldring MB. Degradation of articular cartilage in culture: regulatory factors. In: Woessner JF, Howell DS, eds. Joint cartilage degradation, basic and clinical aspects. New York: Marcel Dekker Inc., 1993:281-345.
44. Bandara G, Lin CW, Georgescu HI, Evans CH. The synovial activation of chondrocytes: evidence for complex cytokine interactions involving a possible novel factor. Biochim Biophys Acta 1992;1134:309-18.
45. Glansbeek HL, van der Kraan PM, Vitters EL, van den Berg WB. Correlation of the type II transforming growth factor β (TGFβ) receptor with TGF-β responses of isolated bovine articular chondrocytes. Ann Rheum Dis 1993;52:812-6.
46. Lohmander LS, Neame PJ, Sandy JD. The structure of aggrecan fragments in human synovial fluid. Arthritis Rheum 1993;36:1214-22.