The prophylactic effect of immunization with DNA encoding herpes simplex virus glycoproteins on HSV-induced disease in guinea pigs

Vaccine

Volumn 15, Issue 8, 1997, Pages 857-860

  McClements, William L ^a   Armstrong, Marcy E ^a   Keys, Robert D ^a   Liu, Margaret A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

DNA vaccination; Guinea pig; Herpes simplex virus; HSV; HSV glycoprotein

Indexed keywords

DNA VACCINE; HERPES VACCINE; VIRUS GLYCOPROTEIN;

ANIMAL EXPERIMENT; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENITAL HERPES; GUINEA PIG; HERPES SIMPLEX VIRUS 2; HUMORAL IMMUNITY; NONHUMAN; PLASMID; PRIORITY JOURNAL; VAGINITIS; VIRUS NEUTRALIZATION;

ANIMALS; DNA, VIRAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GUINEA PIGS; HERPES GENITALIS; HERPESVIRUS 2, HUMAN; PLASMIDS; VACCINES, DNA; VIRAL ENVELOPE PROTEINS; VIRAL VACCINES;

EID: 0030789286     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(96)00246-0     Document Type: Conference Paper

References (9)

1. Whitley, R.J. Herpes simplex viruses. In: Virology, 2nd edn (Eds Fields, B.N. and Knipe, D.M.). Raven Press, New York, 1990, pp. 1843-1887
2. Ulmer, J.B., Donnelly, J.J. and Parker, S.E. et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 1993, 259, 1745-1749
3. Cox, G.J.M., Zamb, T.J. and Babiuk, L.A. Bovine herpesviruses: immune responses in mice and cattle injected with plasmid DNA. J. Virol. 1993, 67, 5664-5667
4. Burke, R.L. Current developments in herpes simplex virus vaccines. Semin. Virol. 1993, 4, 187-197
5. Ghiasi, H., Cai, S., Slanina, S., Nesburn, A.B. and Wechsler, S.L. Vaccination of mice with herpes simplex virus type 1 glycoprotein D DNA produces low levels of protection against lethal HSV-1 challenge. Antiviral Res. 1995, 28, 147-157
6. Manickan, E., Rouse, R.J.D., Yu, Z., Wire, W.S. and Rouse, B.T. Genetic immunization against herpes simplex virus. J. Immunol. 1995, 155, 259-265
7. Stanberry, L.R., Kern, E.R., Richards, J.T., Abbott, T.M. and Overall, J.C.Jr Genital herpes in guinea pigs: pathogenesis of the primary infection and description of recurrent disease. J. Infect. Dis. 1982, 146, 397-404
8. Bourne, N., Stanberry, L.R., Bernstein, D.I. and Lew, D. DNA immunization against experimental genital herpes simplex virus infection. J. Infect. Dis. 1996, 173, 800-807
9. Montgomery, D.L., Shiver, J.W. and Leander, K.R. et al. Heterologous and homologous protection against influenza A by DNA vaccination: optimization of DNA vectors. DNA Cell Biol. 1993, 12, 777-783