A study to determine the pharmacokinetics and inflammatory fluid penetration of two doses of a solid formulation of the hexetil prodrug of a trinem, sanfetrinem (GV 104326)

Antimicrobial Agents and Chemotherapy

Volumn 41, Issue 8, 1997, Pages 1761-1764

  Wise, R ^a   Andrews, J M ^a   Da Ros, L ^b   Child, J ^a   Mortiboy, D ^a  

^a CITY HOSPITAL   (United Kingdom)

^b GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANTHARIDIN; PRODRUG; SANFETRINEM; SANFETRINEM CILEXETIL;

ADULT; AREA UNDER THE CURVE; ARTICLE; DRUG BLOOD LEVEL; DRUG FORMULATION; DRUG HALF LIFE; DRUG PENETRATION; DRUG STABILITY; EXUDATE; HUMAN; HUMAN EXPERIMENT; INFLAMMATION; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; URINE;

EID: 0030789252     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.41.8.1761     Document Type: Article

References (9)

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5. Knight, S. Personal communication.
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8. Wise, R., N. O'Sullivan, J. Johnson, and J. M. Andrews. 1992. Pharmacokinetics and tissue penetration of ampicillin and brobactam following oral administration of 2085P. Antimicrob. Agents Chemother. 36:1002-1004.
9. Wise, R. 1994. Comparative microbiological activity and pharmacokinetics of cefprozil. Eur. J. Clin. Microbiol. Infect. Dis. 13:839-845.