Solution conformations of potent bicyclic antagonists of oxytocin by nuclear magnetic resonance spectroscopy and molecular dynamics simulations

Journal of the American Chemical Society

Volumn 119, Issue 25, 1997, Pages 5833-5846

  Shenderovich, Mark D ^a   Kövér, Katalin E ^a,b   Wilke, Susanne ^a,c   Collins, Nathan ^a,d   Hruby, Victor J ^a  

^a University of Arizona   (United States)

^b UNIVERSITY OF DEBRECEN   (Hungary)

^c HOFFMANN LA ROCHE INC   (United States)

^d Arris Pharmaceutical Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OXYTOCIN; OXYTOCIN ANTAGONIST; OXYTOCIN RECEPTOR;

ARTICLE; CRYSTAL STRUCTURE; DRUG CONFORMATION; DRUG DESIGN; LACTATION; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; THREE DIMENSIONAL IMAGING; UTERUS CONTRACTION;

EID: 0030788469     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja963736y     Document Type: Article

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