Thiamine uptake in human intestinal biopsy specimens, including observations from a patient with acute thiamine deficiency

American Journal of Clinical Nutrition

Volumn 66, Issue 2, 1997, Pages 320-326

  Laforenza, Umberto ^b   Patrini, Cesare ^b   Alvisi, Costanza ^b   Faelli, Alide ^b   Licandro, Anna ^b   Rindi, Gianguido ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b NONE

Author keywords

Human intestinal biopsy; Human thiamine deficiency; Kinetics; Thiamine; Thiamine uptake

Indexed keywords

2,4 DINITROPHENOL; AMPROLIUM; BENEXOL B12; METHYLPREDNISOLONE; OXYTHIAMINE; PYRITHIAMINE; THIAMINE; THIAMINE PYROPHOSPHOKINASE; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; CASE REPORT; COLON BIOPSY; CONTROLLED STUDY; DUODENUM BIOPSY; ERYTHROCYTE; FEMALE; HUMAN; HUMAN TISSUE; INTESTINE ABSORPTION; MALE; ORAL DRUG ADMINISTRATION; STOMACH BIOPSY; THIAMINE DEFICIENCY; TRANSPORT KINETICS;

EID: 0030788091     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/66.2.320     Document Type: Article

References (34)

1. Hoyumpa AM Jr, Middleton HM III, Wilson FA, Schenker S. Thiamine transport across the rat intestine. I. Normal characteristics. Gastroenterology 1975;68:1218-27.
2. Sklan D, Trostler N. Site and extent of thiamin absorption in the rat. J Nutr 1977;107:353-6.
3. Rindi G, Ventura U. Thiamine intestinal transport. Physiol Rev 1972;52:821-7.
4. Morrison AB, Campbell JA. Vitamin absorption studies. I. Factors influencing the excretion of oral test doses of thiamine and riboflavin by human subjects. J Nutr 1960;72:435-40.
5. Friedemann TE, Kunieciak TC, Keegan PK, Sheft BB. The absorption, destruction and excretion of orally administered thiamine by human subjects. Gastroenterology 1948;11:100-14.
6. Thomson AD, Leevy CM. Observations on the mechanism of thiamine hydrochloride absorption in man. Clin Sci 1972;43:153-63.
7. Casirola D, Ferrari G, Gastaldi G, Patrini C, Rindi G. Transport of thiamine by brush border membrane vesicles from rat small intestine. J Physiol (Lond) 1988;398:329-39.
8. +-dependence of thiamin intestinal transport in vitro. Life Sci 1971;10:67-75.
9. Laforenza U, Gastaldi G, Rindi G. Thiamine outflow from the enterocyte: a study using basolateral membrane vesicles from rat small intestine. J Physiol (Lond) 1993;468:401-12.
10. Rindi G, Ferrari G. Thiamine transport by human intestine in vitro. Experientia 1977;33:211-3.
11. Hoyumpa AM Jr, Strickland R, Sheehan JJ, Yarborough G, Nichols S. Dual system of intestinal thiamine transport in humans. J Lab Clin Med 1982;99:701-8.
12. Bettendorff L, Grandfils C, De Ryeker C, Schoffeniels E. Determination of thiamine and its phosphate esters in human blood serum at femtomole levels. J Chromatogr Biomed Appl 1986;382:297-302.
13. Rindi G, Patrini C, Laforenza U, et al. Further studies on erythrocyte thiamin transport and phosphorylation in seven patients with thiamin-responsive megaloblastic anaemia. J Inherit Metab Dis 1994;17:667-77.
14. Lowry OH, Rosenbrough NJ, Farr AR, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-75.
15. Snedecor GW, Cochran WG. Statistical methods. 6th ed. Ames, IA: Iowa State University Press, 1967.
16. Glantz SA. Statistica per discipline biomediche: programma applicative. (Statistics for biomedical disciplines: applicative program.) Milano, Italy: McGraw-Hill Libri Italia, 1988 (in Italian).
17. Weissberg A, Beatty GH. Tables of tolerance-limit factors for normal distributions. Technometrics 1960;2:483-500.
18. Thomson ABR. Unstirred water layer and age-dependent changes in rabbit jejunal D-glucose transport. Am J Physiol 1979;236:E685-91.
19. Gubler CJ. Thiamin. In: Machlin LJ, ed. Handbook of vitamins -nutritional, biochemical, and clinical aspects. New York: Marcel Dekker, Inc, 1984:281-2.
20. Ventura U, Giacalone E, Rindi G. Assorbimento intestinale della tiamina nel ratio in vivo. (In vivo thiamine intestinal absorption in the rat.) Boll Soc Ital Biol Sper 1963;39:1443-6 (in Italian).
21. Rindi G, Ventura U. Phosphorylation and uphill intestinal transport of thiamine in vitro. Experientia 1967;23:175-6.
22. Komai T, Kawai K, Shindo H. Active transport of thiamine from rat small intestine. J Nutr Sci Vitaminol 1974;20:163-77.
23. Rindi G. Thiamin absorption by small intestine. Acta Vitaminol Enzymol 1984;6:47-55.
24. Ricci V, Rindi G. Thiamin uptake by rat isolated enterocytes: relationship between transport and phosphorylation. Arch Int Physiol Biochim Biophys 1992;100:275-9.
25. Warnock LG, Prudhomme CR, Wagner C. The determination of thiamin pyrophosphate in blood and other tissues, and its correlation with erythrocyte transketolase activity. J Nutr 1978;108:421-7.
26. Baines M, Davies G. The evaluation of erythrocyte thiamin diphosphate as an indicator of thiamin status in man, and its comparison with erythrocyte transketolase activity measurements. Ann Clin Biochem 1988;25:698-705.
27. Borgna-Pignatti C, Marradi P, Pinelli L, Monetti N, Patrini C. Thiamine-responsive anemia and DIDMOAD syndrome. J Pediatr 1989;114:405-10.
28. Feldheim W. Changes in enzyme activities induced by nutritional deficiencies. II. Determination of the state of saturation with thiamine by biochemical methods. Int J Vitam Nutr Res 1966;36:197-200.
29. Sanioto SLM, Reinauer H, Hollmann S. Thiamine pyrophosphokinase activity in liver, heart and brain crude extracts of controls and thiamine deficient rats. Int J Vitam Nutr Res 1977;47:315-24.
30. Ferraris RP, Diamond JR. Specific regulation of intestinal nutrient transporters by their dietary substrates. Annu Rev Physiol 1989;51:125-41.
31. Linder MC, Munro HN. The mechanism of iron absorption and its regulation. Fed Proc 1977;36:2017-23.
32. Bonner F. Calcium absorption. In: Johnson LR, ed. Physiology of the gastrointestinal tract. 2nd ed. New York: Raven Press, 1987:1419-35.
33. Hoyumpa AM Jr, Nichols S, Schenker S, Wilson FA. Thiamine transport in thiamine-deficient rats. Role of the unstirred water layer. Biochim Biophys Acta 1976;436:438-47.
34. Patrini C, Cusaro G, Ferrari G, Rindi G. Thiamin transport by rat small intestine "in vitro": influence of endogenous thiamin content of jejunal tissue. Acta Vitaminol Enzymol 1981;3:17-26.