Selective mechanism-based inactivation of peptidylglycine α- hydroxylating monooxygenase in serum and heart atrium vs. Brain

Biochemical Pharmacology

Volumn 53, Issue 11, 1997, Pages 1695-1702

  Bolkenius, Frank N ^a   Ganzhorn, Axel J ^a   Chanal, Marie Christine ^a   Danzin, Charles ^a  

^a SANOFI   (France)

Author keywords

Benzylhydrazine; Mechanism based inhibition; neuropeptide; Peptidylglycine amidating monooxygenase (rat, horse, human); Substance P; Trans styrylacetic acid; Trans styrylthioacetic acid

Indexed keywords

ACETIC ACID DERIVATIVE; ALPHA AMIDATING ENZYME; ENZYME; GLYCINE; HYDRAZINE DERIVATIVE; NEUROPEPTIDE; SUBSTANCE P; SULFIDE;

ARTICLE; BRAIN; CONTROLLED STUDY; ENZYME INHIBITION; HEART ATRIUM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORSE; HUMAN; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SERUM; SPECIES DIFFERENCE;

ANIMALS; BRAIN; FATTY ACIDS, MONOUNSATURATED; HEART ATRIA; HORSES; HUMANS; HYDRAZINES; HYDROGEN-ION CONCENTRATION; KINETICS; MALE; MIXED FUNCTION OXYGENASES; MULTIENZYME COMPLEXES; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY; SUBSTANCE P; SULFHYDRYL COMPOUNDS;

EID: 0030787562     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00051-8     Document Type: Article

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