Effect of chronic clozapine administration on [3H]MK801-binding sites in the rat brain: A side-preference action in cortical areas

Brain Research

Volumn 762, Issue 1-2, 1997, Pages 216-218

  Giardino, Luciana ^a,c   Bortolotti, Francesca ^b   Orazzo, Catello ^b   Pozza, Monica ^c   Monteleone, Palmiero ^b   Calzà, Laura ^d   Maj, Mario ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c HESPERIA HOSPITAL   (Italy)

^d UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

3H MK801; Clozapine; N Methyl D aspartate (NMDA) receptor; Quantitative receptor autoradiography; Rat

Indexed keywords

CLOZAPINE; DIZOCILPINE; GLUTAMATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; TRITIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CAUDATE NUCLEUS; CINGULATE GYRUS; CONTROLLED STUDY; DENTATE GYRUS; DRUG BINDING SITE; HIPPOCAMPUS; MALE; MENTAL DISEASE; MOTOR CORTEX; NONHUMAN; NUCLEUS ACCUMBENS; OLFACTORY BULB; PREFRONTAL CORTEX; PRIORITY JOURNAL; PUTAMEN; RAT; RECEPTOR DENSITY; SCHIZOPHRENIA; SOMATOSENSORY CORTEX;

ANIMALS; ANTIPSYCHOTIC AGENTS; AUTORADIOGRAPHY; BINDING SITES; BRAIN CHEMISTRY; CEREBRAL CORTEX; CLOZAPINE; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; TIME FACTORS; TRITIUM;

EID: 0030787325     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00478-2     Document Type: Article

References (26)

1. Carlson J.N., Glick S.D. Cerebral lateralization as a source of interindividual differences in behavior. Experientia. 45:1989;788-798.
2. Carlson J.N., Fitzgerald L.W., Keller R.W., Glick S.D. Lateralized changes in prefrontal cortical dopamine activity induced by controllable and uncontrollable stress in the rat. Brain Res. 630:1993;178-187.
3. Chiodo L.A., Bunney B.S. Possible mechanisms by which repeated clozapine administration differentially affects the activity of two subpopulations of midbrain dopamine neurons. J. Neurosci. 5:1985;2539-2544.
4. Corbett R. Clozapine but not haloperidol antagonizes an MK-801 discriminative stimulus cue. Pharmacol. Biochem. Behav. 51:1995;561-564.
5. Crowne D.P., Richardson C.M., Dawson K.A. Lateralization of emotionality in right parietal cortex of the rat. Behav. Neurosci. 101:1987;134-138.
6. Daly D.A., Moghaddam B. Actions of clozapine and haloperidol in the extracellular levels of excitatory amino acids in the prefrontal cortex and striatum of conscious rats. Neurosci. Lett. 152:1993;61-64.
7. Deakin J.F.W., Slater P., Simpson M.D.C., Gilchrist A.C., Skan W.J., Royston M.C., Reynolds G.P., Cross A.J. Frontal cortical and left temporal glutamatergic dysfunction in schizophrenia. J. Neurochem. 52:1989;1781-1786.
8. Dunn-Meynell A.A., Levin B.E. Lateralized effect of unilateral somatosensory cortex contusion on behavior and cortical reorganization. Brain Res. 675:1995;143-156.
9. Giardino L. DA1 and DA2 receptor asymmetry is lost in the basal ganglia of old rats. Brain Res. 720:1996;235-238.
10. Giardino L., Ceccatelli S., Puglisi-Allegra S. CRH receptor mRNA expression in two strains of inbred mice and its regulation after repeated restrain stress. Mol. Brain Res. 40:1996;310-314.
11. Grotta J. Safety and tolerability of the glutamate antagonist CGS19755 in acute stroke patients. Stroke. 25:1994;255.
12. Kerwin R.W., Patel S., Meldrum B.S. Quantitative autoradiographic analysis of glutamate binding sites in the hippocampal formation in normal and schizophrenic brain post-mortem. Neuroscience. 39:1990;25-32.
13. Kim J.S., Kornhuber H.H., Schmid-Burgk W., Holzmuller W. Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia. Neurosci. Lett. 20:1980;379-382.
14. Lidsky T.I., Yablonsky-Alter E., Zuck L., Banerjee S.P. Anti-glutamatergic effects of clozapine. Neurosci. Lett. 163:1993;155-158.
15. H.Y. Meltzer, An overview of the mechanism of action of clozapine, J. Clin. Psychiatry, 55 (Suppl. B) (1994) 47-52.
16. Meshul C.K., Bunker G.L., Mason J.N., Allen C., Janowsky A. Effects of subchronic clozapine and haloperidol on striatal glutamatergic synapses. J. Neurochem. 67:1996;1965-1973.
17. J.W. Olney, N.B. Farber, Efficacy of clozapine compared with other antipsychotics in preventing NMDA-antagonist neurotoxicity, J. Clin. Psychiatry, 55 (Suppl. B) (1994) 43-46.
18. Olney J.W., Farber N.B. Glutamate receptor dysfunction and schizophrenia. Arch. Gen. Psychiatry. 52:1995;998-1007.
19. Oretti R.G., Spurlock G., Buckland P.R., McGuffin P. Lack of effect of antipsychotic and antidepressant drugs on glutamate receptor mRNA levels in rats brains. Neurosci. Lett. 177:1994;39-43.
20. G. Paxinos (Ed.), The Rat Nervous System, 2nd Ed., Academic Press, New York, NY, 1995.
21. Potkin, S.G., Buchsbaum, M.S., Jin, Y., Tang, G., Telford, J., Friedman, G., Lottenberg, S., Najafi, A., Gulasekaram, B., Cosat, J., Richmond, G.H., Bunney, W.E., Clozapine effects on glucose metabolic rate in straitum and frontal cortex, J. Clin. Psychiatry, 55 (Suppl. B) (1994) 63-66.
22. Riddle D.R., Purves D. Individual variation and lateral asymmetry of the rat primary somatosensory cortex. J. Neurosci. 15:1995;4184-4195.
23. Sullivan R.M., Szechtman H. Asymmetrical influence of mesocortical dopamine depletion on stress ulcer development and subcortical dopamine systems in rats: implications for psychopathology. Neuroscience. 65:1995;757-766.
24. Syvalahti E.K.G. Biological factors in schizophrenia. Structural and functional aspects. Br. J. Psychiatry. 164:1994;9-14.
25. Toru M., Kurumaji A., Ishimaru M. Excitatory amino acids: implications for psychiatric disorders research. Life Sci. 55:1994;1583-1699.
26. Weinberger D.R., Lipska B. Cortical maldevelopment, anti-psychotic drugs, and schizophrenia: a search for common ground. Scizophrenia Res. 16:1995;87-110.