Effects of alcohol modifiers on the separation of 1-alkoxycarbonylalkyl-pyrrolidine-3-carboxylic acid alkyl ester enantiomers on polysaccharide-based stationary phases

Journal of Liquid Chromatography and Related Technologies

Volumn 20, Issue 14, 1997, Pages 2181-2192

  Lin, Sechoing ^a   Engelsma, Cara ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 [3 (3 METHOXYPHENYL) 2 PROPYNYLOXYIMINO] 1 AZABICYCLO[2.2.1]HEPTANE; ALCOHOL DERIVATIVE; MUSCARINIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; DRUG DETERMINATION; DRUG ISOLATION; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHODOLOGY; STEREOCHEMISTRY;

EID: 0030787294     PISSN: 10826076     EISSN: None     Source Type: Journal    
DOI: 10.1080/10826079708006555     Document Type: Article

References (9)

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6. K. M. Kirkland, "Optimization of Chiral Selectivity on Cellulose-Based High Performance Liquid Chromatographic Columns using Aprotic Mobile-Phase Modifiers," J. Chromatogr., A, 718, 9-26 (1995).
7. A. Kunath, F. Theil, K. Jahnisch, "Influence of the Kind of the Alcoholic Modifiers on Chiral Separation on a Chiralpak AD Column," J. Chromatogr., A, 728, 249-257 (1996).
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9. J. Jaen, S. Barren, M. Brann, M. Callahan, R. Davis, P. Doyle, D. Eubanks, D. Lauffer, L. Lauffer, W. Lipinski, D. Moreland, C. Nelson, C. Raby, R. Schwarz, C. Spencer, H. Tecle, "In Vitro and In Vivo Evaluation of the Subtype-Selective Muscarinic Agonist PD 151832," Life Sciences, 56, 845-852 (1995).