Development of a model of low-inoculum Streptococcus pneumoniae intrapulmonary infection in infant rats

Infection and Immunity

Volumn 65, Issue 11, 1997, Pages 4701-4704

  Saladino, Richard A ^a,d   Stack, Anne M ^a   Fleisher, Gary R ^a   Thompson, Claudette M ^a   Briles, David E ^b   Kobzik, Les ^c   Siber, George R ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b University of Alabama at Birmingham   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTEREMIA; BACTERIAL MENINGITIS; BACTERIAL VIRULENCE; BACTERIUM IDENTIFICATION; CONTROLLED STUDY; FEMALE; MORTALITY; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE;

EID: 0030786745     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.11.4701-4704.1997     Document Type: Article

References (20)

1. Alexander, J. E., R. Lock, C. A. M. Peelers, J. T. Poolman, P. R. Andrew, T. J. Mitchell, D. Hansman, and J. C. Paton. 1994. Immunization of mice with pneumolysin toxoid confers a significant degree of protection against at least nine serotypes of Streptococcus pneumoniae. Infect. Immun. 62:5683-5688.
2. Alonso DeVelasco, E., B. A. T. Dekker, A. F. M. Verheul, R. G. Feldman, J. Verhoef, and H. Snippe. 1995. Anti-polysaccharide immunoglobulin isotype levels and opsonic activity of antisera: relationship with protection against Streptococcus pneumoniae infection in mice. J. Infect. Dis. 172:562-565.
3. Austrian, R. 1981. Some observations on the pneumococcus and on the current status of pneumococcal disease and its prevention. Rev. Infect. Dis. 3(Suppl.):S1-S17.
4. Breiman, R. F., J. S. Spika, V. J. Navarro, P. M. Harden, and C. P. Darby. 1990. Pneumococcal bacteremia in Charleston County, South Carolina. Arch. Intern. Med. 150:1401-1405.
5. Briles, D. E., M. Nahm, K. Schroer, J. Davie, P. Baker, J. Kearney, and R. Barletta. 1981. Antiphosphocholine antibodies found in normal mouse serum are protective against intravenous infection with type 3 Streptococcus pneumoniae. J. Exp. Med. 153:694-705.
6. Friedland, I. R., and G. H. McCracken, Jr. 1994. Management of infections caused by antibiotic-resistant Streptococcus pneumonia? N. Engl. J. Med. 331:377-382.
7. Hoffman, J., M. S. Cetron, M. M. Farley, W. S. Baughman, R. R. Facklam, J. A. Elliott, K. A. Deaver, and R. F. Breiman. 1995. The prevalence of drug-resistant Streptococcus pneumoniae in Atlanta. N. Engl. J. Med. 333: 481-486.
8. Kayhty, H., H. Ahman, P. R. Ronnberg, R. Tillikainen, and J. Eskol. 1995. Pneumococcal polysaccharide-meningococcal outer membrane protein complex conjugate vaccine is immunogenic in infants and children. J. Infect. Dis. 172:1273-1278.
9. MacLeod, C. M., and M. R. Krauss. 1950. Relations of virulence of pneumococcal strains for mice to quantity of capsular polysaccharide formed in vitro. J. Exp. Med. 92:1-9.
10. McClinn, S., and D. Williams. 1996. Incidence of antibiotic-resistant Streptococcus pneumoniae and beta-lactamase-positive Haemophilus influenzae in clinical isolates from patients with otitis media. Pediatr. Infect. Dis. J. 15: S3-S9
11. McCracken, G. H., Jr. 1995. Emergence of resistant Streptococcus pneumoniae: a problem in pediatrics. Pediatr. Infect. Dis. J. 14:424-428.
12. Nielsen, S. V., U. B. S. Sorensen, and J. Henrichsen. 1993. Antibodies against pneumococcal C-polysaccharide are not protective. Microb. Pathog. 14:299-305.
13. Pomat, W. S., D. Lehmann, R. C. Sanders, D. J. Lewis, J. Wilson, S. Rogers, T. Dyke, and M. P. Alpers. 1994. Immunoglobulin G antibody responses to polyvalent pneumococcal vaccine in children in the highlands of Papa New Guinea. Infect. Immun. 62:1848-1853.
14. 2 fragments administered intranasally. J. Infect. Dis 173:1123-1128.
15. Shapiro, E. D., and R. Austrian. 1996. Serotypcs responsible for invasive Streptococcus pneumoniac infections among children in Connecticut. J. In- fect. Dis. 169:212-214.
16. Siber, G. R. 1994. Pncumococcal disease: prospects for a new generation of vaccines. Science 265:1385-1387
17. Tart, R. C., L. S. MCDaniel, B. A. Ralph, and D. E. Briles. 1996 Truncated Streptococcus pneumoniac PspA molecules clicit cross-protective immunity against pneumococcal challenge in mice. J. Infect. Dis. 173:380-386
18. Vella, P. P., S. Marburg, J. M. Staub, P. J. Kniskern, W. Miller, A. Hago- pian, C. lp, R. L. Tolman, C. M. Rusk, and L. S. Chupack. 1992. Immuno- genicity of conjugate vaccines consisting of pneumococcal capsular polysac- charide types 6b. 14. 19f. and 23f and a meningococcal outer membrane protein complex. Infect. Immun. 60:4977-4983.
19. Voss, L., D. Lennon, K. Okesene-Gafa, S. Smeratunga, and D. Martin. 1994 Invasive pneumococcal disease in a pediatric population, Auckland, New Zealand. Pediatr. Infect. Dis. J. 12:873-878.
20. Zangwill, K. M., C. M. Vadheim, A. M. Vannier, L. S. Hemenway, D. P. Greenberg, and J. I. Ward. 1996. Epidemiology of invasive pneumococcal disease in southern California: implications for the design and conduct of a pneumococcal conjugate vaccine efficacy trial. J Infect. Dis. 174:752-759.