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Volumn 29, Issue 6, 1997, Pages 311-316

Transgenic overproduction of islet amyloid polypeptide (amylin) is not sufficient for islet amyloid formation

Author keywords

Hyperglycemia; Insulin; Nicotinic Acid; Non Insulin Dependent Diabetes Mellitus; Pancreatic Beta Cell; Transgenic Mice

Indexed keywords

AMYLIN; AMYLOID; INSULIN; NICOTINIC ACID;

EID: 0030786638     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-979042     Document Type: Conference Paper
Times cited : (21)

References (33)
  • 1
    • 0023025399 scopus 로고
    • A novel peptide in the calcitonin gene related peptide family as an amyloid fibril protein in the endocrine pancreas
    • Westermark P, Wernstedt C, Wilander E, Sletten K: A novel peptide in the calcitonin gene related peptide family as an amyloid fibril protein in the endocrine pancreas. Biochem Biophys Res Commun 140: 827-831 (1986).
    • (1986) Biochem Biophys Res Commun , vol.140 , pp. 827-831
    • Westermark, P.1    Wernstedt, C.2    Wilander, E.3    Sletten, K.4
  • 2
    • 0023192941 scopus 로고
    • Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islets
    • Westermark P, Wernstedt C, Wilander E, Hayden DW, O'Brien TD, Johnson KH: Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islets. Proc Natl Acad Sci USA 84: 3881-3885 (1987).
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 3881-3885
    • Westermark, P.1    Wernstedt, C.2    Wilander, E.3    Hayden, D.W.4    O'Brien, T.D.5    Johnson, K.H.6
  • 3
    • 0023579739 scopus 로고
    • Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients
    • Cooper GJS, Willis AC, Clark A, Turner RC, Sim RB, Reid KBM: Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proc Natl Acad Sci USA 84: 8628-8632 (1987).
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 8628-8632
    • Cooper, G.J.S.1    Willis, A.C.2    Clark, A.3    Turner, R.C.4    Sim, R.B.5    Reid, K.B.M.6
  • 11
    • 0026110135 scopus 로고
    • β-cells in type II diabetes mellitus
    • Porte Jr D: β-cells in type II diabetes mellitus. Diabetes 40: 166-180 (1991).
    • (1991) Diabetes , vol.40 , pp. 166-180
    • Porte Jr., D.1
  • 13
    • 0028301426 scopus 로고
    • Transgenic mice overproducing human islet amyloid polypeptide have increased insulin storage and secretion in vitro
    • Verchere CB, D'Alessio DA, Palmiter RD, Kahn SE: Transgenic mice overproducing human islet amyloid polypeptide have increased insulin storage and secretion in vitro. Diabetologia 37: 725-728 (1994).
    • (1994) Diabetologia , vol.37 , pp. 725-728
    • Verchere, C.B.1    D'Alessio, D.A.2    Palmiter, R.D.3    Kahn, S.E.4
  • 14
    • 0000476083 scopus 로고
    • Immunoassay of insulin: Two antibody system: plasma insulin levels of normal, subdiabetic, and diabetic rats
    • Morgan DR, Lazarow A: Immunoassay of insulin: two antibody system: plasma insulin levels of normal, subdiabetic, and diabetic rats. Diabetes 12: 115-126 (1963).
    • (1963) Diabetes , vol.12 , pp. 115-126
    • Morgan, D.R.1    Lazarow, A.2
  • 15
    • 0029978228 scopus 로고    scopus 로고
    • Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide
    • Verchere CB, D'Alessio DA, Palmiter RD, Weir GC, Bonner-Weir S, Baskin DG, Kahn SE: Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide. Proc Natl Acad Sci USA 93: 3492-3496 (1996).
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3492-3496
    • Verchere, C.B.1    D'Alessio, D.A.2    Palmiter, R.D.3    Weir, G.C.4    Bonner-Weir, S.5    Baskin, D.G.6    Kahn, S.E.7
  • 17
    • 0025875299 scopus 로고
    • Effects of yohimbine and nicotinic acid on insulin secretion in islet transplanted streptozotocin-diabetic rats
    • Ar'Rajab A, Ahren B: Effects of yohimbine and nicotinic acid on insulin secretion in islet transplanted streptozotocin-diabetic rats. Diabetes Res Clin Pract 11: 81-87 (1991).
    • (1991) Diabetes Res Clin Pract , vol.11 , pp. 81-87
    • AR'Rajab, A.1    Ahren, B.2
  • 18
    • 0029126786 scopus 로고
    • Human islet amyloid polypeptide expression in COS 1 cells. A model of intracellular amyloidogenesis
    • O'Brien TD, Butler PC, Kreutter DK, Kane LA, Eberhardt NL: Human islet amyloid polypeptide expression in COS 1 cells. A model of intracellular amyloidogenesis. Am J Pathol 147: 609-616 (1995).
    • (1995) Am J Pathol , vol.147 , pp. 609-616
    • O'Brien, T.D.1    Butler, P.C.2    Kreutter, D.K.3    Kane, L.A.4    Eberhardt, N.L.5
  • 19
    • 0029330879 scopus 로고
    • Amyloid formation in response to beta cell stress occurs in vitro, but not in vivo, in islets of transgenic mice expressing human islet amyloid polypeptide
    • Westermark G, Arora MB, Fox N, Carroll R, Chan SJ, Westermark P, Steiner DF: Amyloid formation in response to beta cell stress occurs in vitro, but not in vivo, in islets of transgenic mice expressing human islet amyloid polypeptide. Mol Med 1: 542-553 (1995).
    • (1995) Mol Med , vol.1 , pp. 542-553
    • Westermark, G.1    Arora, M.B.2    Fox, N.3    Carroll, R.4    Chan, S.J.5    Westermark, P.6    Steiner, D.F.7
  • 21
    • 0029742232 scopus 로고    scopus 로고
    • Treatment with growth hormone and dexamethasone in mice transgenic for human islet amyloid polypeptide causes islet amyloidosis and beta cell dysfunction
    • Couce M, Kane LA, O'Brien TD, Charlesworth J, Soeller W, McNeish J, Kreutter D, Roche P, Butler PC: Treatment with growth hormone and dexamethasone in mice transgenic for human islet amyloid polypeptide causes islet amyloidosis and beta cell dysfunction. Diabetes 45: 1094-1101 (1996).
    • (1996) Diabetes , vol.45 , pp. 1094-1101
    • Couce, M.1    Kane, L.A.2    O'Brien, T.D.3    Charlesworth, J.4    Soeller, W.5    McNeish, J.6    Kreutter, D.7    Roche, P.8    Butler, P.C.9
  • 22
    • 0024463227 scopus 로고
    • Hyperproinsulinemia and amyloid in NIDDM: Clues to etiology of islet β-cell dysfunction?
    • Porte Jr D, Kahn SE: Hyperproinsulinemia and amyloid in NIDDM: clues to etiology of islet β-cell dysfunction? Diabetes 38: 1333-1336 (1989).
    • (1989) Diabetes , vol.38 , pp. 1333-1336
    • Porte Jr., D.1    Kahn, S.E.2
  • 23
    • 0025063525 scopus 로고
    • Diet of second generation Japanese American men with and without non insulin dependent diabetes
    • Tsunehara CH, Leonetti DL, Fujimoto WY: Diet of second generation Japanese American men with and without non insulin dependent diabetes. Am J Clin Nutr 52: 731-738 (1990).
    • (1990) Am J Clin Nutr , vol.52 , pp. 731-738
    • Tsunehara, C.H.1    Leonetti, D.L.2    Fujimoto, W.Y.3
  • 24
    • 0029027767 scopus 로고
    • Defective glucose-stimulated insulin release from perifused islets of C57BL/6J mice
    • Lee SK, Opara EC, Surwit RS, Feinglos MN, Akwari OE: Defective glucose-stimulated insulin release from perifused islets of C57BL/6J mice. Pancreas 11: 206-211 (1995).
    • (1995) Pancreas , vol.11 , pp. 206-211
    • Lee, S.K.1    Opara, E.C.2    Surwit, R.S.3    Feinglos, M.N.4    Akwari, O.E.5
  • 25
    • 0029036835 scopus 로고
    • Long term exposure to fatty acids and ketones inhibits B cell functions in human pancreatic islets of Langerhans
    • Zhou YP, Grill V: Long term exposure to fatty acids and ketones inhibits B cell functions in human pancreatic islets of Langerhans. J Clin Endocrinol Metab 80: 1584-1590 (1995).
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 1584-1590
    • Zhou, Y.P.1    Grill, V.2
  • 26
    • 0028268936 scopus 로고
    • Long term exposure of rat pancreatic islets to fatty acids inhibits glucose induced insulin secretion and biosynthesis through a glucose fatty acid cycle
    • Zhou YP, Grill VE: Long term exposure of rat pancreatic islets to fatty acids inhibits glucose induced insulin secretion and biosynthesis through a glucose fatty acid cycle. J Clin Invest 93: 870-876 (1994).
    • (1994) J Clin Invest , vol.93 , pp. 870-876
    • Zhou, Y.P.1    Grill, V.E.2
  • 27
    • 0028303844 scopus 로고
    • Pancreatic islet cell toxicity of amylin associated with type 2 diabetes mellitus
    • Lorenzo A, Razzaboni B, Weir GC, Yankner BA: Pancreatic islet cell toxicity of amylin associated with type 2 diabetes mellitus. Nature 368: 756-760 (1994).
    • (1994) Nature , vol.368 , pp. 756-760
    • Lorenzo, A.1    Razzaboni, B.2    Weir, G.C.3    Yankner, B.A.4
  • 28
    • 0022496637 scopus 로고
    • Longitudinal studies on the development of diabetes in individual Macaca nigra
    • Howard Jr CF: Longitudinal studies on the development of diabetes in individual Macaca nigra. Diabetologia 29: 301-306 (1986).
    • (1986) Diabetologia , vol.29 , pp. 301-306
    • Howard Jr., C.F.1
  • 30
    • 0021522787 scopus 로고
    • Dexamethasone-induced insulin resistance enhances B-cell responsiveness to glucose level in normal men
    • Beard JC, Halter JB, Best JD, Pfeifer MA, Porte Jr D: Dexamethasone-induced insulin resistance enhances B-cell responsiveness to glucose level in normal men. Am J Physiol 247: E592-E596 (1984).
    • (1984) Am J Physiol , vol.247
    • Beard, J.C.1    Halter, J.B.2    Best, J.D.3    Pfeifer, M.A.4    Porte Jr., D.5
  • 31
    • 0019970112 scopus 로고
    • Effects of growth hormone on insulin action in man. Mechanisms of insulin resistance, impaired suppression of glucose production, and impaired stimulation of glucose utilization
    • Rizza RA, Mandarino LJ, Gerich JE: Effects of growth hormone on insulin action in man. Mechanisms of insulin resistance, impaired suppression of glucose production, and impaired stimulation of glucose utilization. Diabetes 31: 663-669 (1982).
    • (1982) Diabetes , vol.31 , pp. 663-669
    • Rizza, R.A.1    Mandarino, L.J.2    Gerich, J.E.3
  • 32
    • 0027217510 scopus 로고
    • Effect of glucocorticoid and growth hormone treatment on proinsulin levels in humans
    • Kahn SE, Horber FF, Prigeon RL, Haymond MW, Porte Jr D: Effect of glucocorticoid and growth hormone treatment on proinsulin levels in humans. Diabetes 42: 1082-1085 (1993).
    • (1993) Diabetes , vol.42 , pp. 1082-1085
    • Kahn, S.E.1    Horber, F.F.2    Prigeon, R.L.3    Haymond, M.W.4    Porte Jr., D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.