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Volumn 4, Issue 2-3, 1997, Pages 83-90

Apoptosis of L1210 leukemia cells induced by 3-deazaadenosine analogs: Differential expression of c-myc, NF-kappa B and molecular events

Author keywords

3 Deazaadenosine analogs; Apoptosis; C myc; Cell cycle; L1210 lymphocytic leukemia cells; NF kappa B

Indexed keywords

1H IMIDAZO[4,5 C]PYRIDINE 1 ARABINOSIDE; 3 DEAZAADENOSINE; 3 DEAZAARISTEROMYCIN; ANTINEOPLASTIC AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 0030786637     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1007/BF02255598     Document Type: Article
Times cited : (8)

References (42)
  • 1
    • 0027729892 scopus 로고
    • High levels of c-rel expression are associated with programmed cell death in the developing avian embryo and in bone marrow cells in vitro
    • Abbadie C, Kabrun N, Bouali F, Smardova J, Stehelin D, Vandenbunder B, Enrietto PJ. High levels of c-rel expression are associated with programmed cell death in the developing avian embryo and in bone marrow cells in vitro. Cell 75:899-912;1993.
    • (1993) Cell , vol.75 , pp. 899-912
    • Abbadie, C.1    Kabrun, N.2    Bouali, F.3    Smardova, J.4    Stehelin, D.5    Vandenbunder, B.6    Enrietto, P.J.7
  • 2
    • 0025247903 scopus 로고
    • Apoptosis: The roles of the endonculeases
    • Arends MJ, Morris RG, Wyllie AH. Apoptosis: The roles of the endonculeases. Am J Pathol 136:593-608;1990.
    • (1990) Am J Pathol , vol.136 , pp. 593-608
    • Arends, M.J.1    Morris, R.G.2    Wyllie, A.H.3
  • 3
    • 0028174061 scopus 로고
    • Function and activation of NF-κB in the immune system
    • Baeuerle PA, Henkel T. Function and activation of NF-κB in the immune system. Annu Rev Immunol 12:141-179;1994.
    • (1994) Annu Rev Immunol , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 4
    • 0026688162 scopus 로고
    • Apoptotic cell death induced by c-mycis inhibited by bcl-2
    • Bissonnette RP, Echeverri F, Mahboubi A, Green DR. Apoptotic cell death induced by c-mycis inhibited by bcl-2. Nature 359:552-554; 1992.
    • (1992) Nature , vol.359 , pp. 552-554
    • Bissonnette, R.P.1    Echeverri, F.2    Mahboubi, A.3    Green, D.R.4
  • 5
    • 0026668831 scopus 로고
    • Activation of collagen IV gene expression in F9 teratocarcinoma cells by 3-deazaadenosine analogs - Indirect inhibitors of methylation
    • Chiang PK, Burbelo PD, Brugh SA, Gordon RK, Fukuda K, Yamada Y. Activation of collagen IV gene expression in F9 teratocarcinoma cells by 3-deazaadenosine analogs - indirect inhibitors of methylation. J Biol Chem 267: 4988-4991;1992.
    • (1992) J Biol Chem , vol.267 , pp. 4988-4991
    • Chiang, P.K.1    Burbelo, P.D.2    Brugh, S.A.3    Gordon, R.K.4    Fukuda, K.5    Yamada, Y.6
  • 9
    • 0021367846 scopus 로고
    • Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death
    • Cohen JJ, Duke RC. Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death. J Immunol 132:38-42;1984.
    • (1984) J Immunol , vol.132 , pp. 38-42
    • Cohen, J.J.1    Duke, R.C.2
  • 10
    • 0027440979 scopus 로고
    • Cell death initiated by 3-deazaadenosine in HL-60 cells is apoptosis and is partially inhibited by homocysteine
    • Endresen PC, Eide TJ, Aarbakke J. Cell death initiated by 3-deazaadenosine in HL-60 cells is apoptosis and is partially inhibited by homocysteine. Biochem Pharmacol 46:1893-1901; 1993.
    • (1993) Biochem Pharmacol , vol.46 , pp. 1893-1901
    • Endresen, P.C.1    Eide, T.J.2    Aarbakke, J.3
  • 11
    • 0028335913 scopus 로고
    • Homocysteine increases the relative number of apoptotic cells and reduces the relative number of apoptotic bodies in HL-60 cells treated with 3-deazaadenosine
    • Endresen PC, Prytz PS, Lysne S, Aarbakke J. Homocysteine increases the relative number of apoptotic cells and reduces the relative number of apoptotic bodies in HL-60 cells treated with 3-deazaadenosine. J Pharmacol Exp The 269: 1245-1253;1994.
    • (1994) J Pharmacol Exp the , vol.269 , pp. 1245-1253
    • Endresen, P.C.1    Prytz, P.S.2    Lysne, S.3    Aarbakke, J.4
  • 12
    • 0028172869 scopus 로고
    • Inducible phosphorylation of IκBα is not sufficient for its dissociation from NF-κB and is inhibited by protease inhibitors
    • Finco TS, Beg AA, Baldwin Jr AS. Inducible phosphorylation of IκBα is not sufficient for its dissociation from NF-κB and is inhibited by protease inhibitors. Proc Natl Acad Sci USA 91:11884-11888;1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11884-11888
    • Finco, T.S.1    Beg, A.A.2    Baldwin Jr., A.S.3
  • 13
    • 0028009763 scopus 로고
    • Lymphoma models for B cell activation and tolerance. X. Anti-μ-mediated growth arrest and apoptosis of murine B cell lymphomas is prevented by the stabilization of myc
    • Fischer G, Kent SC, Joseph L, Green DR, Scott DW. Lymphoma models for B cell activation and tolerance. X. Anti-μ-mediated growth arrest and apoptosis of murine B cell lymphomas is prevented by the stabilization of myc. J Exp Med 179:221-228;1994.
    • (1994) J Exp Med , vol.179 , pp. 221-228
    • Fischer, G.1    Kent, S.C.2    Joseph, L.3    Green, D.R.4    Scott, D.W.5
  • 14
    • 0023194663 scopus 로고
    • The toxic plant lectins ricin and abrin induce apoptotic changes in mammalian lymphoid tissues and intestine
    • Griffith GD, Leek MD, Gee DJ. The toxic plant lectins ricin and abrin induce apoptotic changes in mammalian lymphoid tissues and intestine. J Pathol 151:221-229;1987.
    • (1987) J Pathol , vol.151 , pp. 221-229
    • Griffith, G.D.1    Leek, M.D.2    Gee, D.J.3
  • 15
    • 0019508989 scopus 로고
    • Adenosine analogs as substrates and inhibitors of S-adenosylhomocysteine hydrolase
    • Guranowski A, Montgomery JA, Cantoni GL, Chiang PK. Adenosine analogs as substrates and inhibitors of S-adenosylhomocysteine hydrolase. Biochemistry 20:110-115;1981.
    • (1981) Biochemistry , vol.20 , pp. 110-115
    • Guranowski, A.1    Montgomery, J.A.2    Cantoni, G.L.3    Chiang, P.K.4
  • 16
    • 0025174809 scopus 로고
    • 3-Deazaadenosine inhibits leukocyte adhesion and ICAM-1 biosynthesis in tumor necrosis factor-stimulated human endothelial cells
    • Jurgenen HC, Huber B, Zimmerman TP, Wolberg G. 3-Deazaadenosine inhibits leukocyte adhesion and ICAM-1 biosynthesis in tumor necrosis factor-stimulated human endothelial cells. J Immunol 144:653-661;1990.
    • (1990) J Immunol , vol.144 , pp. 653-661
    • Jurgenen, H.C.1    Huber, B.2    Zimmerman, T.P.3    Wolberg, G.4
  • 19
    • 0023742874 scopus 로고
    • Adenosine, deoxyadenosine, and deoxyguanosine induce DNA cleavage in mouse thymocytes
    • Kizaki H, Shimada H, Ohsaka F, Sakurada T. Adenosine, deoxyadenosine, and deoxyguanosine induce DNA cleavage in mouse thymocytes. J Immunol 141:1652-1657;1988.
    • (1988) J Immunol , vol.141 , pp. 1652-1657
    • Kizaki, H.1    Shimada, H.2    Ohsaka, F.3    Sakurada, T.4
  • 20
    • 0028981033 scopus 로고
    • Augmentation by aphidicolin 1-β-D-arabinofuranosylcytosine-induced c-jun and NF-κB activation in a human myeloid leukemia cell line: Correlation with apoptosis
    • Kuwakado K, Kubota M, Bessho R, Kataoka A, Usami I, Lin Y, Okuda A, Wakazono Y. Augmentation by aphidicolin 1-β-D-arabinofuranosylcytosine-induced c-jun and NF-κB activation in a human myeloid leukemia cell line: Correlation with apoptosis. Leukemia Res 19: 645-650;1995.
    • (1995) Leukemia Res , vol.19 , pp. 645-650
    • Kuwakado, K.1    Kubota, M.2    Bessho, R.3    Kataoka, A.4    Usami, I.5    Lin, Y.6    Okuda, A.7    Wakazono, Y.8
  • 21
    • 0029020647 scopus 로고
    • Induction of p53 and apoptosis by delta 12-PGJ2 in human hepatocarcinoma SK-HEP-1 cells
    • Lee JH, Kim HS, Jeong SY, Kim IK. Induction of p53 and apoptosis by delta 12-PGJ2 in human hepatocarcinoma SK-HEP-1 cells. FEBS Lett 368:348-352;1995.
    • (1995) FEBS Lett , vol.368 , pp. 348-352
    • Lee, J.H.1    Kim, H.S.2    Jeong, S.Y.3    Kim, I.K.4
  • 22
    • 0028032241 scopus 로고
    • Phosphorylation of NF-κB1-p50 is involved in NF-κB activation and stable DNA binding
    • Li CCH, Dai RM, Chen E, Longo DL. Phosphorylation of NF-κB1-p50 is involved in NF-κB activation and stable DNA binding. J Biol Chem 269:30089-30092;1994.
    • (1994) J Biol Chem , vol.269 , pp. 30089-30092
    • Li, C.C.H.1    Dai, R.M.2    Chen, E.3    Longo, D.L.4
  • 24
    • 0028981050 scopus 로고
    • Activation of NF-κB requires proteolysis of the inhibitor IκBα: Signal-induced phosphorylation of IκBa alone does not release active NF-κB
    • Lin YC, Brown K, Siebenlist U. Activation of NF-κB requires proteolysis of the inhibitor IκBα: Signal-induced phosphorylation of IκBa alone does not release active NF-κB. Proc Natl Acad Sci USA 92:552-556;1995.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 552-556
    • Lin, Y.C.1    Brown, K.2    Siebenlist, U.3
  • 25
    • 0027976193 scopus 로고
    • Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77
    • Liu ZG, Smith SW, McLaughlin KA, Schwartz LM, Osborne BA. Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77. Nature 367:281-283;1994.
    • (1994) Nature , vol.367 , pp. 281-283
    • Liu, Z.G.1    Smith, S.W.2    McLaughlin, K.A.3    Schwartz, L.M.4    Osborne, B.A.5
  • 26
    • 0027246692 scopus 로고
    • Regulation by bcl-2, c-myc and p53 of susceptibility to induction of apoptosis by heat shock and cancer chemotherapy compounds in differentiation competent and defective myeloid leukemic cells
    • Lotem J, Sachs L. Regulation by bcl-2, c-myc and p53 of susceptibility to induction of apoptosis by heat shock and cancer chemotherapy compounds in differentiation competent and defective myeloid leukemic cells. Growth Differ 4:41-47;1993.
    • (1993) Growth Differ , vol.4 , pp. 41-47
    • Lotem, J.1    Sachs, L.2
  • 27
    • 0027319521 scopus 로고
    • p53 is required for radiation-induced apoptosis in mouse thymocytes
    • Lowe SW, Schmitt EM, Smith SW, Osborne BA, Jacks T. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362:847-849;1993.
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmitt, E.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 29
    • 0026627870 scopus 로고
    • Interferon-γ gene expression in human B-cell lines: Induction by interleukin-2, protein kinase C activators, and possible effect of hypomethylation on gene regulation
    • Pang Y, Norihisa Y, Benjamin D, Kantor RRS, Young HA. Interferon-γ gene expression in human B-cell lines: Induction by interleukin-2, protein kinase C activators, and possible effect of hypomethylation on gene regulation. Blood 80:724-732;1992.
    • (1992) Blood , vol.80 , pp. 724-732
    • Pang, Y.1    Norihisa, Y.2    Benjamin, D.3    Kantor, R.R.S.4    Young, H.A.5
  • 30
    • 0028894440 scopus 로고
    • Activation-induced apoptosis in Jurkat cells through a myc-independent mechanism
    • Ruiz-Ruiz MDC, Oliver FJ, Izquierdo M, Lopez-Rivas A. Activation-induced apoptosis in Jurkat cells through a myc-independent mechanism. Mol Immunol 32:947-955;1995.
    • (1995) Mol Immunol , vol.32 , pp. 947-955
    • Ruiz-Ruiz, M.D.C.1    Oliver, F.J.2    Izquierdo, M.3    Lopez-Rivas, A.4
  • 31
    • 0029126754 scopus 로고
    • Redox signaling by transcription factors NF-κB and AP-1 in lymphocytes
    • Schulze-Osthoff K, Los M, Baeuerle PA. Redox signaling by transcription factors NF-κB and AP-1 in lymphocytes. Biochem Pharmacol 50: 735-741;1995.
    • (1995) Biochem Pharmacol , vol.50 , pp. 735-741
    • Schulze-Osthoff, K.1    Los, M.2    Baeuerle, P.A.3
  • 32
    • 0027333347 scopus 로고
    • Programmed cell death, apoptosis and killer genes
    • Schwartz LM, Osborne BA. Programmed cell death, apoptosis and killer genes. Immunol Today 14:582-590;1993.
    • (1993) Immunol Today , vol.14 , pp. 582-590
    • Schwartz, L.M.1    Osborne, B.A.2
  • 33
    • 0023612470 scopus 로고
    • Gene induction by γ-irradiation leads to DNA fragmentation in lymphocytes
    • Sellins KS, Cohen JJ. Gene induction by γ-irradiation leads to DNA fragmentation in lymphocytes. J Immunol 139:3199-3206;1987.
    • (1987) J Immunol , vol.139 , pp. 3199-3206
    • Sellins, K.S.1    Cohen, J.J.2
  • 34
    • 0026786440 scopus 로고
    • 3-Deazaadenosine inhibits thrombin-stimulated platelet-derived growth factor production and endothelial-leukocyte adhesion molecule-1-mediated monocytic cell adhesion in human aortic endothelial cells
    • Shankar R, de la Motte CA, DiCorleto PE. 3-Deazaadenosine inhibits thrombin-stimulated platelet-derived growth factor production and endothelial-leukocyte adhesion molecule-1-mediated monocytic cell adhesion in human aortic endothelial cells. J Biol Chem 267:9376-9382:1992.
    • (1992) J Biol Chem , vol.267 , pp. 9376-9382
    • Shankar, R.1    De La Motte, C.A.2    DiCorleto, P.E.3
  • 37
    • 0029166344 scopus 로고
    • Glucocorticoid antagonist RU 486 reverses agonist-induced apoptosis and c-myc repression in human leukemic CEM-C7 cells
    • Thompson EB, Thulasi R, Saeed MF, Johnson BH. Glucocorticoid antagonist RU 486 reverses agonist-induced apoptosis and c-myc repression in human leukemic CEM-C7 cells. Ann N Y Acad Sci 761:261-265;1995.
    • (1995) Ann N Y Acad Sci , vol.761 , pp. 261-265
    • Thompson, E.B.1    Thulasi, R.2    Saeed, M.F.3    Johnson, B.H.4
  • 40
    • 0028008513 scopus 로고
    • Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas
    • Woronicz JD, Calnan B, Ngo V, Winoto A. Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas. Nature 367:277-281;1994.
    • (1994) Nature , vol.367 , pp. 277-281
    • Woronicz, J.D.1    Calnan, B.2    Ngo, V.3    Winoto, A.4
  • 41
    • 0021346318 scopus 로고
    • Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis
    • Wyllie AH, Morris RG, Smith AL, Dunlop D. Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis. J Pathol 142:67-77;1984.
    • (1984) J Pathol , vol.142 , pp. 67-77
    • Wyllie, A.H.1    Morris, R.G.2    Smith, A.L.3    Dunlop, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.