Interleukin-6 and its soluble receptor regulate the expression of insulin-like growth factor binding protein-5 in osteoblast cultures

Endocrinology

Volumn 138, Issue 8, 1997, Pages 3380-3386

  Franchimont, Nathalie ^a,c   Durant, Deena ^a   Canalis, Ernesto ^a,b  

^a SAINT FRANCIS HOSPITAL AND MEDICAL CENTER   (United States)

^b UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^c Catherine and Weldon Donaghue Found   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; MESSENGER RNA; SOMATOMEDIN BINDING PROTEIN 5;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FETUS; GENE EXPRESSION REGULATION; NONHUMAN; OSTEOBLAST; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; TRANSCRIPTION REGULATION;

EID: 0030786554     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.138.8.5339     Document Type: Article

References (59)

1. Roodman GD 1992 Interleukin-6:an osteotropic factor? J Bone Miner Res 7:475-478
2. Lowik CWGM 1992 Differentiation inducing factors: leukemia inhibitory factor and interleukin-6. In: Gowen M (ed) Cytokines and Bone Metabolism. CRC Press, London, pp 299-324
3. Kurihara N, Civin C, Roodman GD 1991 Osteotropic factor responsiveness of highly purified populations of early and late precursors for human multinucleated cells expressing the osteoclast phenotype. J Bone Miner Res 6:257-261
4. Feyen JHM, Elford P, DePadova FE, Trechsel U 1989 Interleukin-6 is produced by bone and modulated by parathyroid hormone. J Bone Miner Res 4:633-638
5. Franchimont N, Vrindts Y, Gaspar S, Lopez M, Gathy R, DeGroote D, Reginster JY, Franchimont P 1993 Parathyroid hormone (1-34) stimulates and 1,25(OH)2 vitamin D3 inhibits leukemia inhibitory factor (LIF) production by osteoblasts in vitro. In: Christiansen C, Riis B (eds) Proceedings 1993: Fourth International Symposium on Osteoporosis and Consensus Development Conference, Handelstrykkeriet Aalborg Aps, Aalborg, Denmark, pp 249-250
6. Greenfield EM, Shaw SM, Gornik SA, Banks MA 1995 Adenyl cyclase and interleukin 6 are downstream effectors of parathyroid hormone resulting in stimulation of bone resorption. J Clin Invest 96:1238-1244
7. Helle M, Brakenhoff JPJ, DeGroot ER, Aarden LA 1988 Interleukin-6 is involved in interleukin-1 induced activities. Eur J Immunol 18:957-959
8. Fang MA, Hahn TJ 1991 Effects of interleukin-6 on cellular function in UMR-106-01 osteoblast-like cells. J Bone Miner Res 6:133-139
9. Hughes FJ, Howells GL 1993 Interleukin-6 inhibits bone formation in vitro. Bone Miner 21:21-28
10. Taguchi Y, Yamate T, Mocharia H, Lin SC, Vertino A, DeTogni P, Abe E, Manolagas SC 1996 Interleukin-6 induces osteoblast differentiation in uncommitted embryonic fibroblasts (EF). J Bone Miner Res 11[Suppl 1]:S101
11. Hock JM, Centrella M, Canalis E 1988 Insulin-like growth factor I (IGF-I) has independent effects on bone matrix formation and cell replication. Endocrinology 122:254-260
12. Franchimont N, Pash J, Gabbitas B, Canalis E 1996 Interleukin-6 in the presence of its soluble receptor stimulates insulin-like growth factor binding protein-5 expression in osteoblasts. J Bone Miner Res 11[Suppl 1]:S165
13. Delany AM, Pash JM, Canalis E 1994 Cellular and clinical perspectives on skeletal insulin-like growth factor I. J Cell Biochem 55:1-6
14. Rechler MM 1993 Insulin-like growth factor binding proteins. Vitam Horm 47:1-114
15. Hassager C, Fitzpatrick LA, Spencer EM, Riggs BL, Conover CA 1992 Basal and regulated secretion of insulin-like growth factor binding proteins in osteoblast-like cells is cell line specific. J Clin Endocrinol Metab 75:228-233
16. Okazaki R, Riggs BL, Conover CA 1994 Glucocorticoid regulation of insulin-like growth factor binding protein expression in normal human osteoblast-like cells. Endocrinology 134:126-132
17. McCarthy T, Casinghino S, Centrella M, Canalis E 1994 Complex pattern of insulin-like growth factor binding protein expression in primary rat osteoblast enriched cultures: regulation by prostaglandin E2, growth hormone, and the insulin-like growth factors. J Cell Physiol 160:163-175
18. Andress DL, Birnbaum RS 1992 Human osteoblast-derived insulin-like growth factor (IGF) binding protein-5 stimulates osteoblast mitogenesis and potentiates IGF action. J Biol Chem 267:22467-22472
19. Dong Y, Canalis E 1995 Insulin-like growth factor I and retinoic acid induce the synthesis of insulin-like growth factor binding protein-5 in rat osteoblastic cells. Endocrinology 136:2000-2006
20. Canalis E, Gabbitas B 1995 Skeletal growth factors regulate the synthesis of insulin-like growth factor binding protein-5 in bone cell cultures. J Biol Chem 270:10771-10776
21. Gabbitas B, Pash JM, Delany A, Canalis, E 1996 Cortisol inhibits the synthesis of insulin-like growth factor binding protein-5 in bone cell cultures by trancriptional mechanisms. J Biol Chem 271:9033-9038
22. Canalis E, Pash J, Gabbitas B, Rydziel S, Varghese S 1993 Growth factors regulate the synthesis of insulin like growth factor I in bone cell cultures. Endocrinology 133:33-38
23. Birnbaum RS, Wiren KM 1994 Changes in insulin-like growth factor-binding protein expression and secretion during the proliferation, differentiation, and mineralization of primary cultures of rat osteoblasts. Endocrinology 135:223-230
24. Rose-John S, Ehlers M, Grotzinger J, Mullberg J 1995 The soluble interleukin-6 receptor. Ann NY Acad Sci 762:207-221
25. Tamura T, Udagawa N, Takahashi N, Miyaura C, Tanaka S, Yamada Y, Koishihara Y, Ohsugi Y, Kumaki K, Taga T, Kishimoto T, Suda T 1993 Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6. Proc Natl Acad Sci USA 90:11924-11928
26. McCarthy TL, Centrella M, Canalis E 1988 Further biochemical and molecular characterization of primary rat parietal bone cell cultures. J Bone Miner Res 3:401-408
27. Knudsen BS, Harpel PC, Nachman RL 1987 Plasminogen activator inhibitor is associated with the extracellular matrix of cultured bovine smooth muscle cells. J Clin Invest 80:1082-1089
28. Jones JJ, Gockerman A, Busby, Jr, WH, Camacho-Hubner C, Clemmons DR 1993 Extracellular matrix contains insulin-like growth factor binding protein-5: Potentiation of the effects of IGF-I. J Cell Biol 121:679-687
29. Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidiniumn thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
30. Shimasaki S, Shimonaka M, Zhang HP, Ling N 1991 Identification of five different insulin-like growth factor binding proteins (IGFBPs) from adult rat serum and molecular cloning of a novel IGFBP-5 in rat and human. J Biol Chem 266:10646-10653
31. Feinberg A, Volgelstein B 1984 A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 137:266-267
32. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K 1995 Current Protocols in Molecular Biology Preparation and analysis of RNA 4.10.5 to 4.10.9
33. Greenberg ME, Ziff EB 1984 Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature 311:433-438
34. Laemmli UK 1970 Cleavage of structural protein during the assembly of the head bacteriophage T4. Nature 277:680-685
35. Sokal RR, Rohlf FJ 1981 Biometry, ed 2. Freeman, San Francisco
36. Centrella M, McCarthy TL, Canalis E 1991 Glucocorticoid regulation of transforming growth factor β, (TGF β) activity and binding in osteoblast-enriched cultures from fetal rat bone. Mol Cell Biol 11:4490-4496
37. Zandomeni R, Bunick D, Ackerman S, Mittleman B, Weinmann R 1983 Mechanism of action of DRB. Effect on specific in vitro initiation of transcription. J Mol Biol 167:561-574
38. Thrailkill KM, Quarles LD, Nagase H, Suzuki K, Serra DM, Fowlkes JL 1995 Characterization of insulin-like growth factor-binding protein 5-degrading proteases produced throughout murine osteoblast differentiation. Endocrinology 136:3527-3533
39. Camacho-Hubner C, Busby, Jr, WH, McCusker RH, Wright G, Clemmons DR 1992 Identification of the forms of insulin-like growth factor-binding proteins produced by human fibroblasts and the mechanisms that regulate their secretion. J Biol Chem 267:11949-11956
40. Salvesen G, Nagase H 1989 Inhibition of proteolytic enzymes. In: Beynon RJ, Bond JS (eds) Proteolytic Enzymes: A Practical Approach. Oxford University Press, Oxford, UK, p 91
41. Jilka RL, Hangoc G, Girasole G, Passeri G, Williams DC, Abrams JS, Boyce B, Broxmeyer H, Manolagas SC 1992 Increased osteoclast development after estrogen loss: mediation by interleukin-6. Science 257:88-91
42. Klein B, Zhang XG, Lu ZY, Bataille R 1995 Interleukin-6 in human multiple myeloma. Blood 85:863-872
43. Bataille R, Chappard D, Klein B 1992 The critical role of interleukin-6, interleukin-1β and macrophage colony-stimulating factor in the pathogenesis of bone lesions in multiple myeloma. Int J Clin Lab Res 21:283-287
44. Canalis E, Pash J, Varghese S 1993 Skeletal growth factors. Crit Rev Eukaryot Gene Expr 3:155-166
45. Frieling JTM, Sauerwein RW, Wijdenes J, Hendriks T, van der Linden CJ 1994 Soluble interleukin 6 receptor in biological fluids from human origin. Cytokine 6:376-381
46. Suzuki H, Yasukawa K, Saito T, Narazaki M, Hasegawa A, Taga T, Kishimoto T 1993 Serum soluble interleukin-6 receptor in MRL/lpr mice is elevated with age and mediates the interleukin-6 signal. Eur J Immunol 23:1078-1082
47. Franchimont N, Canalis E 1995 Platelet-derived growth factor stimulates the synthesis of interleukin-6 in cells of the osteoblast lineage. Endocrinology 136:5469-5475
48. Pash JM, Canalis E 1996 Transcriptional regulation of insulin-like growth factor-binding protein-5 by prostaglandin E2 in osteoblast cells. Endocrinology 137:2375-2382
49. Conover CA, Kiefer MC 1993 Regulation and biological effect of endogenous insulin-like growth factor binding protein-5 in human osteoblastic cells. J Clin Endocrinol Metab 76:1153-1159
50. Chen-Kiang S, Hsu W, Natkunam Y, Zhang X 1993 Nuclear signaling by interleukin-6. Curr Opin Immunol 5:124-128
51. Wegenka UM, Buschmann J, Lutticken C, Heinrich PC, Friedemann H 1993 Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level. Mol Cell Biol 13:276-288
52. Zhang D, Sun M, Samols D, Kushner I 1996 STAT3 participates in transcriptional activation of the C-reactive protein gene by interleukin-6. J Biol Chem 271:9503-9509
53. Heinrich PC, Graeve L, Rose-John S, Schneider-Mergener J, Dittrich E, Erren A, Gerhartz C, Ulrike H, Lutticken C, Wegenka U, Weiergraber O, Horn F 1995 Membrane-bound and soluble interleukin-6 receptor: studies on structure, regulation of expression, and signal transduction. Ann NY Acad Sci 762:222-237
54. Kou K, Mittanck D, Fu C, Rotwein P 1995 Structure and function of the mouse insulin-like growth factor binding protein-5 gene promoter. DNA Cell Biol 14:241-249
55. Feyen JH, Evans DB, Binkert C, Heinrich GF, Geisse S, Kocher HP 1991 Recombinant human (Cvs281) insulin-like growth factor-binding protein 2 inhibits both basal and insulin-like growth factor I-stimulated proliferation and collagen synthesis in fetal rat calvariae. J Biol Chem 266:19469-19474
56. LaTour D, Mohan S, Linkhart TA, Baylink DJ, Strong DD 1990 Inhibitory insulin-like growth factor-binding protein: cloning, complete sequence, and physiological regulation. Mol Endocrinol 4:1806-1814
57. Nam TJ, Busby, Jr, WH, Clemmons DR 1996 Characterization and determination of the relative abundance of two types of insulin-like growth factor binding protein-5 proteases that are secreted by human fibroblasts. Endocrinology 137:5530-5536
58. Fowlkes JL, Thrailkill KM, Serra DM, Suzuki K, Nagase H 1995 Matrix metalloproteinases as insulin-like growth factor binding protein-degrading proteinases. Prog Growth Factor Res 6:255-263
59. Franchimont N, Rydziel S, Delany A, Canalis E 1997 Interleukin-6 and its soluble receptor cause a marked induction of collagenase 3 expression in rat osteoblast cultures. J Biol Chem 272:12144-12150