The preparation of substituted 1(2H)-isoquinolinones from dilithiated 2- methyl-N-arylbenzamides, 2-methyl-N-(arylmethyl)-benzamides, or 2- methylbenzoic acid, 2,2-dimethylhydrazide

Synthetic Communications

Volumn 27, Issue 17, 1997, Pages 2961-2969

  Davis, Sharon E ^a   Church, A Cameron ^a   Griffith, Cynthia L ^a   Beam, Charles F ^a  

^a School of Business   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZAMIDE DERIVATIVE; ISOCARBOSTYRIL DERIVATIVE;

ARTICLE; CHEMICAL REACTION; SYNTHESIS;

EID: 0030786462     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397919708005002     Document Type: Article

References (53)

1. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
2. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
3. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
4. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
5. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
6. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
7. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
8. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
9. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
10. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
11. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
12. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
13. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
14. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
15. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
16. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
17. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
18. Select preparations to 1980: (a) Haimova, M.A., Ognyanov, V.I. and Mollov, N.M. Synthesis 1980, 845. (b) Shamma, M., and Mionot, J.L., "Isoquinoline Alkaloid Research", Plenum Press, New York, New York, 1978, p. 51. (c) i Iida, H., Kawano, K., Kikuchi, T. and Yoshimizu, F. Yakuggaka Zasshi 1976, 96, 176. (d) Belgaonkar, V.H. and Usgoankar, R.N. Tetrahedron Lett. 1975, 3849. (e) Valeters, R. and Zin'kovskaya, V.R. Latv. PSR Zinat. Akad. Vestis, Kim, Ser. 1973, 310; Chem. Abstr. 1973, 79, 91351. (f) Tirodkar, R.B. and Usgaonkar, R.N. Indian J. Chem., Sect. B 1972, 10, 1060. (g) Van der Goot, H. and Nauta, W. Th. Chim. Ther. 1972, 7, 185. (h) Kronberg, L. and Danielsson, B. Acta Pharm. Suecica 1971, 8, 373. (i) Van der Goot, H. and Nauta, W., Th. Acta Pharm. Suecica 1971, 8, 373. (j) Pelletier, S.W., "Chemistry of Alkaloids", Van Nostrand Reinhold Co., New York, New York, 1970, p. 77. (k) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1970, 2240. (1) Eloy, F. and Deryckere, A. Helv. Chem. Acta 1969, 52, 1755. (m) Legrand, L. and Lozac'h, N. Bull. Soc. Chim. Fr. 1966, 3828. (n) Ishikawa, M., Yamada, S., Hotta, H. and Kaneko, C. Chem. Pharm. Bull. 1966, 14, 1102. (o) Prey, V., Kerres, B. and Berbalk, H. Monatsh. 1960, 91, 774. (p) Berti, G. and Corti, P. Gazz. Chim. Ital., 1958, 88, 704. (q) Fisher, N.I. and Hamer, F.M. J. Chem. Soc. 1934, 1905.
19. Select preparations since 1980: (a) Delcey, M.C., Huel, C., and Bisagni, E. Heterocycles 1995, 41, 1721. (b) Izumi, T. and Morishita, N. J. Heterocycl. Chem. 1994, 31, 145. (c) Cobas, A., Guitian, E. and Castedo, L. J. Org. Chem. 1993, 58, 3113. (d) Couture, A., Cornet, H. and Grandclaudon, P. Tetrahedron 1992, 48, 3857. (e) Singh, R., Singh, P.R. and Srivastaya, J.N. J. Indian Chem. Soc. 1991, 68, 276. (f) Couture, A., Grandclaudon, P. and Hooijer, S. J. Org. Chem. 1991, 56, 4977. (g) Girling, I.R. and Widdowson, D.A. J. Chem. Soc., Perkin Trans 1 1988, 1317. (h) Couture, A. and Grandclaudon, P. Synthesis, 1986, 576. (i) Stanoeva, E., Haimova, M. and Ognyanov, V. Liebigs Ann., Chem. 1984, 389. (j) Larock, R.C., Liu, C.-L., Lau, H.H. and Varaprath, S. Tetrahedron Lett. 1984, 25, 4459. (k) Kitamura, T., Kobayashi, S. and Taniguchi, H. Chem. Lett. 1984, 1523. (l) Stanoeva, E., Haimova, M.A. and Ognyanov, V.I. Liebigs Ann. Chem. 1984, 389. (m) Girling, I.R. and Widdowson, D.A. Tetrahedron Lett. 1982, 23, 1957. (n) Kaneko, C., Naito, T. and Miwa, C. Chem. Pharm. Bull. 1982, 30, 752. (o) Wolfbeis, O.S. Liebigs Ann., Chem. 1981, 819. (p) Beugelmans, R. and Bios-Choussy, M. Synthesis 1981, 729.
20. Select preparations since 1980: (a) Delcey, M.C., Huel, C., and Bisagni, E. Heterocycles 1995, 41, 1721. (b) Izumi, T. and Morishita, N. J. Heterocycl. Chem. 1994, 31, 145. (c) Cobas, A., Guitian, E. and Castedo, L. J. Org. Chem. 1993, 58, 3113. (d) Couture, A., Cornet, H. and Grandclaudon, P. Tetrahedron 1992, 48, 3857. (e) Singh, R., Singh, P.R. and Srivastaya, J.N. J. Indian Chem. Soc. 1991, 68, 276. (f) Couture, A., Grandclaudon, P. and Hooijer, S. J. Org. Chem. 1991, 56, 4977. (g) Girling, I.R. and Widdowson, D.A. J. Chem. Soc., Perkin Trans 1 1988, 1317. (h) Couture, A. and Grandclaudon, P. Synthesis, 1986, 576. (i) Stanoeva, E., Haimova, M. and Ognyanov, V. Liebigs Ann., Chem. 1984, 389. (j) Larock, R.C., Liu, C.-L., Lau, H.H. and Varaprath, S. Tetrahedron Lett. 1984, 25, 4459. (k) Kitamura, T., Kobayashi, S. and Taniguchi, H. Chem. Lett. 1984, 1523. (l) Stanoeva, E., Haimova, M.A. and Ognyanov, V.I. Liebigs Ann. Chem. 1984, 389. (m) Girling, I.R. and Widdowson, D.A. Tetrahedron Lett. 1982, 23, 1957. (n) Kaneko, C., Naito, T. and Miwa, C. Chem. Pharm. Bull. 1982, 30, 752. (o) Wolfbeis, O.S. Liebigs Ann., Chem. 1981, 819. (p) Beugelmans, R. and Bios-Choussy, M. Synthesis 1981, 729.
21. Select preparations since 1980: (a) Delcey, M.C., Huel, C., and Bisagni, E. Heterocycles 1995, 41, 1721. (b) Izumi, T. and Morishita, N. J. Heterocycl. Chem. 1994, 31, 145. (c) Cobas, A., Guitian, E. and Castedo, L. J. Org. Chem. 1993, 58, 3113. (d) Couture, A., Cornet, H. and Grandclaudon, P. Tetrahedron 1992, 48, 3857. (e) Singh, R., Singh, P.R. and Srivastaya, J.N. J. Indian Chem. Soc. 1991, 68, 276. (f) Couture, A., Grandclaudon, P. and Hooijer, S. J. Org. Chem. 1991, 56, 4977. (g) Girling, I.R. and Widdowson, D.A. J. Chem. Soc., Perkin Trans 1 1988, 1317. (h) Couture, A. and Grandclaudon, P. Synthesis, 1986, 576. (i) Stanoeva, E., Haimova, M. and Ognyanov, V. Liebigs Ann., Chem. 1984, 389. (j) Larock, R.C., Liu, C.-L., Lau, H.H. and Varaprath, S. Tetrahedron Lett. 1984, 25, 4459. (k) Kitamura, T., Kobayashi, S. and Taniguchi, H. Chem. Lett. 1984, 1523. (l) Stanoeva, E., Haimova, M.A. and Ognyanov, V.I. Liebigs Ann. Chem. 1984, 389. (m) Girling, I.R. and Widdowson, D.A. Tetrahedron Lett. 1982, 23, 1957. (n) Kaneko, C., Naito, T. and Miwa, C. Chem. Pharm. Bull. 1982, 30, 752. (o) Wolfbeis, O.S. Liebigs Ann., Chem. 1981, 819. (p) Beugelmans, R. and Bios-Choussy, M. Synthesis 1981, 729.
22. Select preparations since 1980: (a) Delcey, M.C., Huel, C., and Bisagni, E. Heterocycles 1995, 41, 1721. (b) Izumi, T. and Morishita, N. J. Heterocycl. Chem. 1994, 31, 145. (c) Cobas, A., Guitian, E. and Castedo, L. J. Org. Chem. 1993, 58, 3113. (d) Couture, A., Cornet, H. and Grandclaudon, P. Tetrahedron 1992, 48, 3857. (e) Singh, R., Singh, P.R. and Srivastaya, J.N. J. Indian Chem. Soc. 1991, 68, 276. (f) Couture, A., Grandclaudon, P. and Hooijer, S. J. Org. Chem. 1991, 56, 4977. (g) Girling, I.R. and Widdowson, D.A. J. Chem. Soc., Perkin Trans 1 1988, 1317. (h) Couture, A. and Grandclaudon, P. Synthesis, 1986, 576. (i) Stanoeva, E., Haimova, M. and Ognyanov, V. Liebigs Ann., Chem. 1984, 389. (j) Larock, R.C., Liu, C.-L., Lau, H.H. and Varaprath, S. Tetrahedron Lett. 1984, 25, 4459. (k) Kitamura, T., Kobayashi, S. and Taniguchi, H. Chem. Lett. 1984, 1523. (l) Stanoeva, E., Haimova, M.A. and Ognyanov, V.I. Liebigs Ann. Chem. 1984, 389. (m) Girling, I.R. and Widdowson, D.A. Tetrahedron Lett. 1982, 23, 1957. (n) Kaneko, C., Naito, T. and Miwa, C. Chem. Pharm. Bull. 1982, 30, 752. (o) Wolfbeis, O.S. Liebigs Ann., Chem. 1981, 819. (p) Beugelmans, R. and Bios-Choussy, M. Synthesis 1981, 729.
23. Select preparations since 1980: (a) Delcey, M.C., Huel, C., and Bisagni, E. Heterocycles 1995, 41, 1721. (b) Izumi, T. and Morishita, N. J. Heterocycl. Chem. 1994, 31, 145. (c) Cobas, A., Guitian, E. and Castedo, L. J. Org. Chem. 1993, 58, 3113. (d) Couture, A., Cornet, H. and Grandclaudon, P. Tetrahedron 1992, 48, 3857. (e) Singh, R., Singh, P.R. and Srivastaya, J.N. J. Indian Chem. Soc. 1991, 68, 276. (f) Couture, A., Grandclaudon, P. and Hooijer, S. J. Org. Chem. 1991, 56, 4977. (g) Girling, I.R. and Widdowson, D.A. J. Chem. Soc., Perkin Trans 1 1988, 1317. (h) Couture, A. and Grandclaudon, P. Synthesis, 1986, 576. (i) Stanoeva, E., Haimova, M. and Ognyanov, V. Liebigs Ann., Chem. 1984, 389. (j) Larock, R.C., Liu, C.-L., Lau, H.H. and Varaprath, S. Tetrahedron Lett. 1984, 25, 4459. (k) Kitamura, T., Kobayashi, S. and Taniguchi, H. Chem. Lett. 1984, 1523. (l) Stanoeva, E., Haimova, M.A. and Ognyanov, V.I. Liebigs Ann. Chem. 1984, 389. (m) Girling, I.R. and Widdowson, D.A. Tetrahedron Lett. 1982, 23, 1957. (n) Kaneko, C., Naito, T. and Miwa, C. Chem. Pharm. Bull. 1982, 30, 752. (o) Wolfbeis, O.S. Liebigs Ann., Chem. 1981, 819. (p) Beugelmans, R. and Bios-Choussy, M. Synthesis 1981, 729.
24. Select preparations since 1980: (a) Delcey, M.C., Huel, C., and Bisagni, E. Heterocycles 1995, 41, 1721. (b) Izumi, T. and Morishita, N. J. Heterocycl. Chem. 1994, 31, 145. (c) Cobas, A., Guitian, E. and Castedo, L. J. Org. Chem. 1993, 58, 3113. (d) Couture, A., Cornet, H. and Grandclaudon, P. Tetrahedron 1992, 48, 3857. (e) Singh, R., Singh, P.R. and Srivastaya, J.N. J. Indian Chem. Soc. 1991, 68, 276. (f) Couture, A., Grandclaudon, P. and Hooijer, S. J. Org. Chem. 1991, 56, 4977. (g) Girling, I.R. and Widdowson, D.A. J. Chem. Soc., Perkin Trans 1 1988, 1317. (h) Couture, A. and Grandclaudon, P. Synthesis, 1986, 576. (i) Stanoeva, E., Haimova, M. and Ognyanov, V. Liebigs Ann., Chem. 1984, 389. (j) Larock, R.C., Liu, C.-L., Lau, H.H. and Varaprath, S. Tetrahedron Lett. 1984, 25, 4459. (k) Kitamura, T., Kobayashi, S. and Taniguchi, H. Chem. Lett. 1984, 1523. (l) Stanoeva, E., Haimova, M.A. and Ognyanov, V.I. Liebigs Ann. Chem. 1984, 389. (m) Girling, I.R. and Widdowson, D.A. Tetrahedron Lett. 1982, 23, 1957. (n) Kaneko, C., Naito, T. and Miwa, C. Chem. Pharm. Bull. 1982, 30, 752. (o) Wolfbeis, O.S. Liebigs Ann., Chem. 1981, 819. (p) Beugelmans, R. and Bios-Choussy, M. Synthesis 1981, 729.
25. Select preparations since 1980: (a) Delcey, M.C., Huel, C., and Bisagni, E. Heterocycles 1995, 41, 1721. (b) Izumi, T. and Morishita, N. J. Heterocycl. Chem. 1994, 31, 145. (c) Cobas, A., Guitian, E. and Castedo, L. J. Org. Chem. 1993, 58, 3113. (d) Couture, A., Cornet, H. and Grandclaudon, P. Tetrahedron 1992, 48, 3857. (e) Singh, R., Singh, P.R. and Srivastaya, J.N. J. Indian Chem. Soc. 1991, 68, 276. (f) Couture, A., Grandclaudon, P. and Hooijer, S. J. Org. Chem. 1991, 56, 4977. (g) Girling, I.R. and Widdowson, D.A. J. Chem. Soc., Perkin Trans 1 1988, 1317. (h) Couture, A. and Grandclaudon, P. Synthesis, 1986, 576. (i) Stanoeva, E., Haimova, M. and Ognyanov, V. Liebigs Ann., Chem. 1984, 389. (j) Larock, R.C., Liu, C.-L., Lau, H.H. and Varaprath, S. Tetrahedron Lett. 1984, 25, 4459. (k) Kitamura, T., Kobayashi, S. and Taniguchi, H. Chem. Lett. 1984, 1523. (l) Stanoeva, E., Haimova, M.A. and Ognyanov, V.I. Liebigs Ann. Chem. 1984, 389. (m) Girling, I.R. and Widdowson, D.A. Tetrahedron Lett. 1982, 23, 1957. (n) Kaneko, C., Naito, T. and Miwa, C. Chem. Pharm. Bull. 1982, 30, 752. (o) Wolfbeis, O.S. Liebigs Ann., Chem. 1981, 819. (p) Beugelmans, R. and Bios-Choussy, M. Synthesis 1981, 729.
26. Select preparations since 1980: (a) Delcey, M.C., Huel, C., and Bisagni, E. Heterocycles 1995, 41, 1721. (b) Izumi, T. and Morishita, N. J. Heterocycl. Chem. 1994, 31, 145. (c) Cobas, A., Guitian, E. and Castedo, L. J. Org. Chem. 1993, 58, 3113. (d) Couture, A., Cornet, H. and Grandclaudon, P. Tetrahedron 1992, 48, 3857. (e) Singh, R., Singh, P.R. and Srivastaya, J.N. J. Indian Chem. Soc. 1991, 68, 276. (f) Couture, A., Grandclaudon, P. and Hooijer, S. J. Org. Chem. 1991, 56, 4977. (g) Girling, I.R. and Widdowson, D.A. J. Chem. Soc., Perkin Trans 1 1988, 1317. (h) Couture, A. and Grandclaudon, P. Synthesis, 1986, 576. (i) Stanoeva, E., Haimova, M. and Ognyanov, V. Liebigs Ann., Chem. 1984, 389. (j) Larock, R.C., Liu, C.-L., Lau, H.H. and Varaprath, S. Tetrahedron Lett. 1984, 25, 4459. (k) Kitamura, T., Kobayashi, S. and Taniguchi, H. Chem. Lett. 1984, 1523. (l) Stanoeva, E., Haimova, M.A. and Ognyanov, V.I. Liebigs Ann. Chem. 1984, 389. (m) Girling, I.R. and Widdowson, D.A. Tetrahedron Lett. 1982, 23, 1957. (n) Kaneko, C., Naito, T. and Miwa, C. Chem. Pharm. Bull. 1982, 30, 752. (o) Wolfbeis, O.S. Liebigs Ann., Chem. 1981, 819. (p) Beugelmans, R. and Bios-Choussy, M. Synthesis 1981, 729.
27. Select preparations since 1980: (a) Delcey, M.C., Huel, C., and Bisagni, E. Heterocycles 1995, 41, 1721. (b) Izumi, T. and Morishita, N. J. Heterocycl. Chem. 1994, 31, 145. (c) Cobas, A., Guitian, E. and Castedo, L. J. Org. Chem. 1993, 58, 3113. (d) Couture, A., Cornet, H. and Grandclaudon, P. Tetrahedron 1992, 48, 3857. (e) Singh, R., Singh, P.R. and Srivastaya, J.N. J. Indian Chem. Soc. 1991, 68, 276. (f) Couture, A., Grandclaudon, P. and Hooijer, S. J. Org. Chem. 1991, 56, 4977. (g) Girling, I.R. and Widdowson, D.A. J. Chem. Soc., Perkin Trans 1 1988, 1317. (h) Couture, A. and Grandclaudon, P. Synthesis, 1986, 576. (i) Stanoeva, E., Haimova, M. and Ognyanov, V. Liebigs Ann., Chem. 1984, 389. (j) Larock, R.C., Liu, C.-L., Lau, H.H. and Varaprath, S. Tetrahedron Lett. 1984, 25, 4459. (k) Kitamura, T., Kobayashi, S. and Taniguchi, H. Chem. Lett. 1984, 1523. (l) Stanoeva, E., Haimova, M.A. and Ognyanov, V.I. Liebigs Ann. Chem. 1984, 389. (m) Girling, I.R. and Widdowson, D.A. Tetrahedron Lett. 1982, 23, 1957. (n) Kaneko, C., Naito, T. and Miwa, C. Chem. Pharm. Bull. 1982, 30, 752. (o) Wolfbeis, O.S. Liebigs Ann., Chem. 1981, 819. (p) Beugelmans, R. and Bios-Choussy, M. Synthesis 1981, 729.
28. Select preparations since 1980: (a) Delcey, M.C., Huel, C., and Bisagni, E. Heterocycles 1995, 41, 1721. (b) Izumi, T. and Morishita, N. J. Heterocycl. Chem. 1994, 31, 145. (c) Cobas, A., Guitian, E. and Castedo, L. J. Org. Chem. 1993, 58, 3113. (d) Couture, A., Cornet, H. and Grandclaudon, P. Tetrahedron 1992, 48, 3857. (e) Singh, R., Singh, P.R. and Srivastaya, J.N. J. Indian Chem. Soc. 1991, 68, 276. (f) Couture, A., Grandclaudon, P. and Hooijer, S. J. Org. Chem. 1991, 56, 4977. (g) Girling, I.R. and Widdowson, D.A. J. Chem. Soc., Perkin Trans 1 1988, 1317. (h) Couture, A. and Grandclaudon, P. Synthesis, 1986, 576. (i) Stanoeva, E., Haimova, M. and Ognyanov, V. Liebigs Ann., Chem. 1984, 389. (j) Larock, R.C., Liu, C.-L., Lau, H.H. and Varaprath, S. Tetrahedron Lett. 1984, 25, 4459. (k) Kitamura, T., Kobayashi, S. and Taniguchi, H. Chem. Lett. 1984, 1523. (l) Stanoeva, E., Haimova, M.A. and Ognyanov, V.I. Liebigs Ann. Chem. 1984, 389. (m) Girling, I.R. and Widdowson, D.A. Tetrahedron Lett. 1982, 23, 1957. (n) Kaneko, C., Naito, T. and Miwa, C. Chem. Pharm. Bull. 1982, 30, 752. (o) Wolfbeis, O.S. Liebigs Ann., Chem. 1981, 819. (p) Beugelmans, R. and Bios-Choussy, M. Synthesis 1981, 729.
29. Select preparations since 1980: (a) Delcey, M.C., Huel, C., and Bisagni, E. Heterocycles 1995, 41, 1721. (b) Izumi, T. and Morishita, N. J. Heterocycl. Chem. 1994, 31, 145. (c) Cobas, A., Guitian, E. and Castedo, L. J. Org. Chem. 1993, 58, 3113. (d) Couture, A., Cornet, H. and Grandclaudon, P. Tetrahedron 1992, 48, 3857. (e) Singh, R., Singh, P.R. and Srivastaya, J.N. J. Indian Chem. Soc. 1991, 68, 276. (f) Couture, A., Grandclaudon, P. and Hooijer, S. J. Org. Chem. 1991, 56, 4977. (g) Girling, I.R. and Widdowson, D.A. J. Chem. Soc., Perkin Trans 1 1988, 1317. (h) Couture, A. and Grandclaudon, P. Synthesis, 1986, 576. (i) Stanoeva, E., Haimova, M. and Ognyanov, V. Liebigs Ann., Chem. 1984, 389. (j) Larock, R.C., Liu, C.-L., Lau, H.H. and Varaprath, S. Tetrahedron Lett. 1984, 25, 4459. (k) Kitamura, T., Kobayashi, S. and Taniguchi, H. Chem. Lett. 1984, 1523. (l) Stanoeva, E., Haimova, M.A. and Ognyanov, V.I. Liebigs Ann. Chem. 1984, 389. (m) Girling, I.R. and Widdowson, D.A. Tetrahedron Lett. 1982, 23, 1957. (n) Kaneko, C., Naito, T. and Miwa, C. Chem. Pharm. Bull. 1982, 30, 752. (o) Wolfbeis, O.S. Liebigs Ann., Chem. 1981, 819. (p) Beugelmans, R. and Bios-Choussy, M. Synthesis 1981, 729.
30. Select preparations since 1980: (a) Delcey, M.C., Huel, C., and Bisagni, E. Heterocycles 1995, 41, 1721. (b) Izumi, T. and Morishita, N. J. Heterocycl. Chem. 1994, 31, 145. (c) Cobas, A., Guitian, E. and Castedo, L. J. Org. Chem. 1993, 58, 3113. (d) Couture, A., Cornet, H. and Grandclaudon, P. Tetrahedron 1992, 48, 3857. (e) Singh, R., Singh, P.R. and Srivastaya, J.N. J. Indian Chem. Soc. 1991, 68, 276. (f) Couture, A., Grandclaudon, P. and Hooijer, S. J. Org. Chem. 1991, 56, 4977. (g) Girling, I.R. and Widdowson, D.A. J. Chem. Soc., Perkin Trans 1 1988, 1317. (h) Couture, A. and Grandclaudon, P. Synthesis, 1986, 576. (i) Stanoeva, E., Haimova, M. and Ognyanov, V. Liebigs Ann., Chem. 1984, 389. (j) Larock, R.C., Liu, C.-L., Lau, H.H. and Varaprath, S. Tetrahedron Lett. 1984, 25, 4459. (k) Kitamura, T., Kobayashi, S. and Taniguchi, H. Chem. Lett. 1984, 1523. (l) Stanoeva, E., Haimova, M.A. and Ognyanov, V.I. Liebigs Ann. Chem. 1984, 389. (m) Girling, I.R. and Widdowson, D.A. Tetrahedron Lett. 1982, 23, 1957. (n) Kaneko, C., Naito, T. and Miwa, C. Chem. Pharm. Bull. 1982, 30, 752. (o) Wolfbeis, O.S. Liebigs Ann., Chem. 1981, 819. (p) Beugelmans, R. and Bios-Choussy, M. Synthesis 1981, 729.
31. Select preparations since 1980: (a) Delcey, M.C., Huel, C., and Bisagni, E. Heterocycles 1995, 41, 1721. (b) Izumi, T. and Morishita, N. J. Heterocycl. Chem. 1994, 31, 145. (c) Cobas, A., Guitian, E. and Castedo, L. J. Org. Chem. 1993, 58, 3113. (d) Couture, A., Cornet, H. and Grandclaudon, P. Tetrahedron 1992, 48, 3857. (e) Singh, R., Singh, P.R. and Srivastaya, J.N. J. Indian Chem. Soc. 1991, 68, 276. (f) Couture, A., Grandclaudon, P. and Hooijer, S. J. Org. Chem. 1991, 56, 4977. (g) Girling, I.R. and Widdowson, D.A. J. Chem. Soc., Perkin Trans 1 1988, 1317. (h) Couture, A. and Grandclaudon, P. Synthesis, 1986, 576. (i) Stanoeva, E., Haimova, M. and Ognyanov, V. Liebigs Ann., Chem. 1984, 389. (j) Larock, R.C., Liu, C.-L., Lau, H.H. and Varaprath, S. Tetrahedron Lett. 1984, 25, 4459. (k) Kitamura, T., Kobayashi, S. and Taniguchi, H. Chem. Lett. 1984, 1523. (l) Stanoeva, E., Haimova, M.A. and Ognyanov, V.I. Liebigs Ann. Chem. 1984, 389. (m) Girling, I.R. and Widdowson, D.A. Tetrahedron Lett. 1982, 23, 1957. (n) Kaneko, C., Naito, T. and Miwa, C. Chem. Pharm. Bull. 1982, 30, 752. (o) Wolfbeis, O.S. Liebigs Ann., Chem. 1981, 819. (p) Beugelmans, R. and Bios-Choussy, M. Synthesis 1981, 729.
32. Select preparations since 1980: (a) Delcey, M.C., Huel, C., and Bisagni, E. Heterocycles 1995, 41, 1721. (b) Izumi, T. and Morishita, N. J. Heterocycl. Chem. 1994, 31, 145. (c) Cobas, A., Guitian, E. and Castedo, L. J. Org. Chem. 1993, 58, 3113. (d) Couture, A., Cornet, H. and Grandclaudon, P. Tetrahedron 1992, 48, 3857. (e) Singh, R., Singh, P.R. and Srivastaya, J.N. J. Indian Chem. Soc. 1991, 68, 276. (f) Couture, A., Grandclaudon, P. and Hooijer, S. J. Org. Chem. 1991, 56, 4977. (g) Girling, I.R. and Widdowson, D.A. J. Chem. Soc., Perkin Trans 1 1988, 1317. (h) Couture, A. and Grandclaudon, P. Synthesis, 1986, 576. (i) Stanoeva, E., Haimova, M. and Ognyanov, V. Liebigs Ann., Chem. 1984, 389. (j) Larock, R.C., Liu, C.-L., Lau, H.H. and Varaprath, S. Tetrahedron Lett. 1984, 25, 4459. (k) Kitamura, T., Kobayashi, S. and Taniguchi, H. Chem. Lett. 1984, 1523. (l) Stanoeva, E., Haimova, M.A. and Ognyanov, V.I. Liebigs Ann. Chem. 1984, 389. (m) Girling, I.R. and Widdowson, D.A. Tetrahedron Lett. 1982, 23, 1957. (n) Kaneko, C., Naito, T. and Miwa, C. Chem. Pharm. Bull. 1982, 30, 752. (o) Wolfbeis, O.S. Liebigs Ann., Chem. 1981, 819. (p) Beugelmans, R. and Bios-Choussy, M. Synthesis 1981, 729.
33. Select preparations since 1980: (a) Delcey, M.C., Huel, C., and Bisagni, E. Heterocycles 1995, 41, 1721. (b) Izumi, T. and Morishita, N. J. Heterocycl. Chem. 1994, 31, 145. (c) Cobas, A., Guitian, E. and Castedo, L. J. Org. Chem. 1993, 58, 3113. (d) Couture, A., Cornet, H. and Grandclaudon, P. Tetrahedron 1992, 48, 3857. (e) Singh, R., Singh, P.R. and Srivastaya, J.N. J. Indian Chem. Soc. 1991, 68, 276. (f) Couture, A., Grandclaudon, P. and Hooijer, S. J. Org. Chem. 1991, 56, 4977. (g) Girling, I.R. and Widdowson, D.A. J. Chem. Soc., Perkin Trans 1 1988, 1317. (h) Couture, A. and Grandclaudon, P. Synthesis, 1986, 576. (i) Stanoeva, E., Haimova, M. and Ognyanov, V. Liebigs Ann., Chem. 1984, 389. (j) Larock, R.C., Liu, C.-L., Lau, H.H. and Varaprath, S. Tetrahedron Lett. 1984, 25, 4459. (k) Kitamura, T., Kobayashi, S. and Taniguchi, H. Chem. Lett. 1984, 1523. (l) Stanoeva, E., Haimova, M.A. and Ognyanov, V.I. Liebigs Ann. Chem. 1984, 389. (m) Girling, I.R. and Widdowson, D.A. Tetrahedron Lett. 1982, 23, 1957. (n) Kaneko, C., Naito, T. and Miwa, C. Chem. Pharm. Bull. 1982, 30, 752. (o) Wolfbeis, O.S. Liebigs Ann., Chem. 1981, 819. (p) Beugelmans, R. and Bios-Choussy, M. Synthesis 1981, 729.
34. Select preparations since 1980: (a) Delcey, M.C., Huel, C., and Bisagni, E. Heterocycles 1995, 41, 1721. (b) Izumi, T. and Morishita, N. J. Heterocycl. Chem. 1994, 31, 145. (c) Cobas, A., Guitian, E. and Castedo, L. J. Org. Chem. 1993, 58, 3113. (d) Couture, A., Cornet, H. and Grandclaudon, P. Tetrahedron 1992, 48, 3857. (e) Singh, R., Singh, P.R. and Srivastaya, J.N. J. Indian Chem. Soc. 1991, 68, 276. (f) Couture, A., Grandclaudon, P. and Hooijer, S. J. Org. Chem. 1991, 56, 4977. (g) Girling, I.R. and Widdowson, D.A. J. Chem. Soc., Perkin Trans 1 1988, 1317. (h) Couture, A. and Grandclaudon, P. Synthesis, 1986, 576. (i) Stanoeva, E., Haimova, M. and Ognyanov, V. Liebigs Ann., Chem. 1984, 389. (j) Larock, R.C., Liu, C.-L., Lau, H.H. and Varaprath, S. Tetrahedron Lett. 1984, 25, 4459. (k) Kitamura, T., Kobayashi, S. and Taniguchi, H. Chem. Lett. 1984, 1523. (l) Stanoeva, E., Haimova, M.A. and Ognyanov, V.I. Liebigs Ann. Chem. 1984, 389. (m) Girling, I.R. and Widdowson, D.A. Tetrahedron Lett. 1982, 23, 1957. (n) Kaneko, C., Naito, T. and Miwa, C. Chem. Pharm. Bull. 1982, 30, 752. (o) Wolfbeis, O.S. Liebigs Ann., Chem. 1981, 819. (p) Beugelmans, R. and Bios-Choussy, M. Synthesis 1981, 729.
35. Strong-Base Methods: (a) Couture, A., Cornet, H., and Grandclaudon, P. Tetrahedron Lett. 1993, 34, 8097. (b) Couture, A., Cornet, H. and Grandclaudon, P. J. Organometal. Chem. 1992, 440, 7. (c) Cuevas, J.-C. and Snieckus, V. Tetrahedron Lett. 1989, 30, 5837. (d) Mali, R.S., Kuklarni, B.K., and Shankaran, K. Synthesis 1982, 329. (e) Abraham, T. Monatsh. Chem. 1982, 113, 371. (f) Poindexter, G.S. J. Org. Chem. 1982, 47, 3787. (g) Boyce, W.T. and Levine, R. J. Org. Chem. 1966, 31, 3807. (h) Vaulx R.L., Puterbaugh, W.H., and Hauser, C.R. J. Org. Chem. 1964, 29, 3514.
36. Strong-Base Methods: (a) Couture, A., Cornet, H., and Grandclaudon, P. Tetrahedron Lett. 1993, 34, 8097. (b) Couture, A., Cornet, H. and Grandclaudon, P. J. Organometal. Chem. 1992, 440, 7. (c) Cuevas, J.-C. and Snieckus, V. Tetrahedron Lett. 1989, 30, 5837. (d) Mali, R.S., Kuklarni, B.K., and Shankaran, K. Synthesis 1982, 329. (e) Abraham, T. Monatsh. Chem. 1982, 113, 371. (f) Poindexter, G.S. J. Org. Chem. 1982, 47, 3787. (g) Boyce, W.T. and Levine, R. J. Org. Chem. 1966, 31, 3807. (h) Vaulx R.L., Puterbaugh, W.H., and Hauser, C.R. J. Org. Chem. 1964, 29, 3514.
37. Strong-Base Methods: (a) Couture, A., Cornet, H., and Grandclaudon, P. Tetrahedron Lett. 1993, 34, 8097. (b) Couture, A., Cornet, H. and Grandclaudon, P. J. Organometal. Chem. 1992, 440, 7. (c) Cuevas, J.-C. and Snieckus, V. Tetrahedron Lett. 1989, 30, 5837. (d) Mali, R.S., Kuklarni, B.K., and Shankaran, K. Synthesis 1982, 329. (e) Abraham, T. Monatsh. Chem. 1982, 113, 371. (f) Poindexter, G.S. J. Org. Chem. 1982, 47, 3787. (g) Boyce, W.T. and Levine, R. J. Org. Chem. 1966, 31, 3807. (h) Vaulx R.L., Puterbaugh, W.H., and Hauser, C.R. J. Org. Chem. 1964, 29, 3514.
38. Strong-Base Methods: (a) Couture, A., Cornet, H., and Grandclaudon, P. Tetrahedron Lett. 1993, 34, 8097. (b) Couture, A., Cornet, H. and Grandclaudon, P. J. Organometal. Chem. 1992, 440, 7. (c) Cuevas, J.-C. and Snieckus, V. Tetrahedron Lett. 1989, 30, 5837. (d) Mali, R.S., Kuklarni, B.K., and Shankaran, K. Synthesis 1982, 329. (e) Abraham, T. Monatsh. Chem. 1982, 113, 371. (f) Poindexter, G.S. J. Org. Chem. 1982, 47, 3787. (g) Boyce, W.T. and Levine, R. J. Org. Chem. 1966, 31, 3807. (h) Vaulx R.L., Puterbaugh, W.H., and Hauser, C.R. J. Org. Chem. 1964, 29, 3514.
39. Strong-Base Methods: (a) Couture, A., Cornet, H., and Grandclaudon, P. Tetrahedron Lett. 1993, 34, 8097. (b) Couture, A., Cornet, H. and Grandclaudon, P. J. Organometal. Chem. 1992, 440, 7. (c) Cuevas, J.-C. and Snieckus, V. Tetrahedron Lett. 1989, 30, 5837. (d) Mali, R.S., Kuklarni, B.K., and Shankaran, K. Synthesis 1982, 329. (e) Abraham, T. Monatsh. Chem. 1982, 113, 371. (f) Poindexter, G.S. J. Org. Chem. 1982, 47, 3787. (g) Boyce, W.T. and Levine, R. J. Org. Chem. 1966, 31, 3807. (h) Vaulx R.L., Puterbaugh, W.H., and Hauser, C.R. J. Org. Chem. 1964, 29, 3514.
40. Strong-Base Methods: (a) Couture, A., Cornet, H., and Grandclaudon, P. Tetrahedron Lett. 1993, 34, 8097. (b) Couture, A., Cornet, H. and Grandclaudon, P. J. Organometal. Chem. 1992, 440, 7. (c) Cuevas, J.-C. and Snieckus, V. Tetrahedron Lett. 1989, 30, 5837. (d) Mali, R.S., Kuklarni, B.K., and Shankaran, K. Synthesis 1982, 329. (e) Abraham, T. Monatsh. Chem. 1982, 113, 371. (f) Poindexter, G.S. J. Org. Chem. 1982, 47, 3787. (g) Boyce, W.T. and Levine, R. J. Org. Chem. 1966, 31, 3807. (h) Vaulx R.L., Puterbaugh, W.H., and Hauser, C.R. J. Org. Chem. 1964, 29, 3514.
41. Strong-Base Methods: (a) Couture, A., Cornet, H., and Grandclaudon, P. Tetrahedron Lett. 1993, 34, 8097. (b) Couture, A., Cornet, H. and Grandclaudon, P. J. Organometal. Chem. 1992, 440, 7. (c) Cuevas, J.-C. and Snieckus, V. Tetrahedron Lett. 1989, 30, 5837. (d) Mali, R.S., Kuklarni, B.K., and Shankaran, K. Synthesis 1982, 329. (e) Abraham, T. Monatsh. Chem. 1982, 113, 371. (f) Poindexter, G.S. J. Org. Chem. 1982, 47, 3787. (g) Boyce, W.T. and Levine, R. J. Org. Chem. 1966, 31, 3807. (h) Vaulx R.L., Puterbaugh, W.H., and Hauser, C.R. J. Org. Chem. 1964, 29, 3514.
42. Strong-Base Methods: (a) Couture, A., Cornet, H., and Grandclaudon, P. Tetrahedron Lett. 1993, 34, 8097. (b) Couture, A., Cornet, H. and Grandclaudon, P. J. Organometal. Chem. 1992, 440, 7. (c) Cuevas, J.-C. and Snieckus, V. Tetrahedron Lett. 1989, 30, 5837. (d) Mali, R.S., Kuklarni, B.K., and Shankaran, K. Synthesis 1982, 329. (e) Abraham, T. Monatsh. Chem. 1982, 113, 371. (f) Poindexter, G.S. J. Org. Chem. 1982, 47, 3787. (g) Boyce, W.T. and Levine, R. J. Org. Chem. 1966, 31, 3807. (h) Vaulx R.L., Puterbaugh, W.H., and Hauser, C.R. J. Org. Chem. 1964, 29, 3514.
43. Koller, M.U., Church, A.C., (Mazat) Griffith, C.L., Hines, M.A., Lachicotte, R.J., Taylor, R.A., and Beam, C.F. Synthetic Communications 1996, 26, 1763.
44. Select references for starting materials, (a) 2-Methyl-N-phenylbenzamide: Katritzky, A.R. and Fan, W.Q. Org. Prep. Proced. Int. 1987, 19, 263. (b) 2-Methyl-N-(4-methylphenyl)-benzamide: Grammaticakis, P. Compt. Rend. 1962, 255, 1456. (c) 2-Methyl-N-(3-methoxyphenyl)-benzamide: White, G.A. Pestic Biochem. Physiol. 1987, 27, 249. (d) 2-Methyl-N-(phenylmethyl)-benzamide: White, G.A. Pestic Biochem. Physiol. 1989,34, 255.
45. Select references for starting materials, (a) 2-Methyl-N-phenylbenzamide: Katritzky, A.R. and Fan, W.Q. Org. Prep. Proced. Int. 1987, 19, 263. (b) 2-Methyl-N-(4-methylphenyl)-benzamide: Grammaticakis, P. Compt. Rend. 1962, 255, 1456. (c) 2-Methyl-N-(3-methoxyphenyl)-benzamide: White, G.A. Pestic Biochem. Physiol. 1987, 27, 249. (d) 2-Methyl-N-(phenylmethyl)-benzamide: White, G.A. Pestic Biochem. Physiol. 1989,34, 255.
46. Select references for starting materials, (a) 2-Methyl-N-phenylbenzamide: Katritzky, A.R. and Fan, W.Q. Org. Prep. Proced. Int. 1987, 19, 263. (b) 2-Methyl-N-(4-methylphenyl)-benzamide: Grammaticakis, P. Compt. Rend. 1962, 255, 1456. (c) 2-Methyl-N-(3-methoxyphenyl)-benzamide: White, G.A. Pestic Biochem. Physiol. 1987, 27, 249. (d) 2-Methyl-N-(phenylmethyl)-benzamide: White, G.A. Pestic Biochem. Physiol. 1989,34, 255.
47. Select references for starting materials, (a) 2-Methyl-N-phenylbenzamide: Katritzky, A.R. and Fan, W.Q. Org. Prep. Proced. Int. 1987, 19, 263. (b) 2-Methyl-N-(4-methylphenyl)-benzamide: Grammaticakis, P. Compt. Rend. 1962, 255, 1456. (c) 2-Methyl-N-(3-methoxyphenyl)-benzamide: White, G.A. Pestic Biochem. Physiol. 1987, 27, 249. (d) 2-Methyl-N-(phenylmethyl)-benzamide: White, G.A. Pestic Biochem. Physiol. 1989,34, 255.
48. 2-Methylbenzoic acid, 2,2-dimethylhydrazide: This compound has been made and used on the limited occasions cited, (a) Meyer, R.F. and Cummings, B.L. J. Heterocycl. Chem. 1964, 1, 186. (b) Benderly, A. and Stravchansky, S. Tetrahedron Lett. 1988, 29, 739. (c) Yushmanova, T.I., Lopyrev, V.A. and Voronkov, M.G. Izv. Akad. Nauk. SSSR, Ser. Khim. 1988, 460; Chem. Abstr. 1988, 110, 75608c.
49. 2-Methylbenzoic acid, 2,2-dimethylhydrazide: This compound has been made and used on the limited occasions cited, (a) Meyer, R.F. and Cummings, B.L. J. Heterocycl. Chem. 1964, 1, 186. (b) Benderly, A. and Stravchansky, S. Tetrahedron Lett. 1988, 29, 739. (c) Yushmanova, T.I., Lopyrev, V.A. and Voronkov, M.G. Izv. Akad. Nauk. SSSR, Ser. Khim. 1988, 460; Chem. Abstr. 1988, 110, 75608c.
50. 2-Methylbenzoic acid, 2,2-dimethylhydrazide: This compound has been made and used on the limited occasions cited, (a) Meyer, R.F. and Cummings, B.L. J. Heterocycl. Chem. 1964, 1, 186. (b) Benderly, A. and Stravchansky, S. Tetrahedron Lett. 1988, 29, 739. (c) Yushmanova, T.I., Lopyrev, V.A. and Voronkov, M.G. Izv. Akad. Nauk. SSSR, Ser. Khim. 1988, 460; Chem. Abstr. 1988, 110, 75608c.
51. 2-Methylbenzoic acid, 2,2-dimethylhydrazide: This compound has been made and used on the limited occasions cited, (a) Meyer, R.F. and Cummings, B.L. J. Heterocycl. Chem. 1964, 1, 186. (b) Benderly, A. and Stravchansky, S. Tetrahedron Lett. 1988, 29, 739. (c) Yushmanova, T.I., Lopyrev, V.A. and Voronkov, M.G. Izv. Akad. Nauk. SSSR, Ser. Khim. 1988, 460; Chem. Abstr. 1988, 110, 75608c.
52. 2-), and 7.27 -7.60 (m, ArH).
53. Combustion analysis for C, H, and N were performed by Quantitative Technologies, Inc., P.O. Box 470, Salem Industrial Park, Bldg. 5, Whitehouse, NJ 08888. [Compd. No. from Table] Calcd. for 2: C, 76.02; H, 4.25; N, 4.22. Found: C, 75.88; H, 4.56; N, 4.02. Calcd. for 3: C, 77.29; H, 5.36; N, 3.92. Found: C, 77.00; H, 5.53; N, 3.85. Calcd. for 4: C, 81.43; H, 6.57; N, 3.65. Found: C, 81.16; H, 6.72; N, 3.57. Calcd. for 5: C, 80.92; H, 5.61; N, 4.10. Found: C, 80.85; H, 5.74; N, 3.97. Calcd. for 6: C, 80.49; H, 4.82; N, 4.47. Found: C, 80.55; H, 4.78; N, 4.40. Calcd. for 7: C, 76.77; H, 5.04; N, 3.89. Found: C, 76.65; H, 5.43; N, 3.93. Calcd. for 8: C, 81.10; H, 5.95; N, 3.94. Found: C, 81.08; H, 6.11; N, 3.87. Calcd. for 9: C, 76.77; H, 5.04; N, 3.89. Found: C, 76.63; H, 5.38; N, 3.73. Calcd. for 10: C, 76.41; H, 4.66; N, 4.05. Found: C, 76.59; H, 4.88; N, 4.18. Calcd. for 11: C, 80.92; H, 5.61; N, 4.10. Found: C, 80.59; H, 5.60; N, 4.12. Calcd. for 12: C, 77.25; H, 6.10; N, 10.60. Found: C, 77.34; H, 6.23; N, 10.51. Calcd. for 13: C, 77.67; H, 6.52; N, 10.06. Found: C, 77.60; H, 6.76; N, 9.82. Calcd. for 14: C, 67.78; H, 6.26; N, 7.90. Found: C, 67.84; H, 6.26; N, 7.83. Calcd. for 15: C, 73.45; H, 6.16; N, 9.52. Found: C, 73.54; H, 6.18; N, 9.48. Calcd. for 16: C, 80.30; H, 7.16; N, 5.85. Found: C, 80.27; H, 7.03; N, 5.81.