Use of native and recombinant bactericidal/permeability-increasing proteins (BPI) as antigens for detection of BPI-ANCA

Journal of Immunological Methods

Volumn 205, Issue 2, 1997, Pages 127-133

  Schultz, Hendrik ^a   Csernok, Elena ^a   Johnston, Thomas W ^a   Lockwood, Christopher M ^b   Gross, Wolfgang L ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Antineutrophil cytoplasmic autoantibody; Bactericidal; Enzyme linked immunosorbent assay; Permeability increasing protein

Indexed keywords

BACTERICIDAL PERMEABILITY INCREASING PROTEIN; NEUTROPHIL CYTOPLASMIC ANTIBODY; RECOMBINANT PROTEIN;

ANTIGEN DETECTION; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; PRIORITY JOURNAL;

ANIMALS; ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; ANTIGENS; ANTIMICROBIAL CATIONIC PEPTIDES; BLOOD BACTERICIDAL ACTIVITY; BLOOD PROTEINS; CASE-CONTROL STUDIES; CHO CELLS; CRICETINAE; CYSTIC FIBROSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLYCOSYLATION; HUMANS; INFLAMMATORY BOWEL DISEASES; MEMBRANE PROTEINS; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS;

MURINAE;

EID: 0030786412     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(97)00067-7     Document Type: Article

References (19)

1. Cohen Tervaert, J.W., Huitema, M.G., Hene, R.J., Sluiter, W.J., The, T.H., van der Hem, G.K., Kallenberg, C.G., 1990. Prevention of relapses in Wegener's granulomatosis by treatment based on antineutrophil cytoplasmic antibody titre. Lancet 336, 709.
2. Elsbach, P., Weiss, J., 1995. Prospects for use of recombinant BPI in the treatment of Gram-negative infections. Infect. Agents Dis. 4, 102.
3. Gazzano-Santoro, H., Parent, J.B., Grinna, L., Horwitz, A., Parsons, T., Theofan, G., Elsbach, P., Weiss, J., Conlon, P.J., 1992. High-affinity binding of the bactericidal/permeability increasing protein and a recombinant amino-terminal fragment to the Lipid A region of lipopolysaccharide. Infect. Immun. 60 (11), 4754.
4. Gray, P.W., Flaggs, G., Leong, S.R., Gumina, R.J., Weiss, J., Ooi, C.E., Elsbach, P., 1989. Cloning of the cDNA of a human neutrophil bactericidal protein. Structural and functional correlations. J. Biol. Chem. 264, 9505.
5. Gross, W.L., Schmitt, W.H., Csernok, E., 1993. ANCA and associated diseases: immunodiagnostic and pathogenetic aspects. Clin. Exp. Immunol. 91, 1.
6. Gross, W.L., Csernok, E., Helmchen, U., 1995. Antineutrophil cytoplasmic autoantibodies, autoantigens, and systemic vasculitis. APMIS 103, 81.
7. Hagen, E.C., Andrassy, K., Csernok, E., Daha, M.R., Gaskin, G., Gross, W.L., Lesavre, P., Lüdemann, J., Pusey, C.D., Rasmussen, N., Savage, C.O.S., Sinico, A., Wiik, A., van der Woude, F.J., 1993. The value of indirect immunofluorescence and solid phase techniques for ANCA detection: a report on the first phase of an international cooperative study on the standardization of ANCA assays. J. Immunol. Methods 159, 1.
8. Jones, S.J., Zhao, M.H., Elliot, J.D., Lockwood, C.M., 1995. The antigenicity of bactericidal/permeability increasing protein (BPI) is threatened by serine proteases. Clin. Exp. Immunol. 101 (Suppl. 1), 36.
9. Lüdemann, J., Csernok, E., Ulmer, M., Lemke, H., Utecht, B., Rautmann, A., Gross, W.L., 1990. Anti-neutrophil cytoplasmic antibodies in Wegener's granulomatosis: immunodiagnostic value, monoclonal antibodies and characterization of the target antigen. Neth. J. Med. 36, 152.
10. Moguilevsky, N., Garcia-Quintana, L., Jaquet, A., Tournay, C., Fabry, L., Pierard, L., Bollen, A., 1991. Structural and biological properties of human recombinant myeloperoxidase produced by Chinese hamster ovary cells lines. Eur. J. Biochem. 197, 605.
11. Ooi, C.E., Weiss, J., Doerfler, M.E., Elsbach, P., 1991. Endotoxin-neutralizing properties of the 25 kD N-terminal fragment and a newly isolated 30 kD C-terminal fragment of the 55-60 kD bactericidal/permeability increasing protein of human neutrophils. J. Exp. Med. 174, 649.
12. Pereira, H.A., Spitznagel, J.K., Winton, E.F., Shafer, W.M., Martin, L.E., Guzman, G.S., Pohl, J., Scott, R.W., Marra, M.N., Kinkade, J.M., 1990. The ontogeny of a 57 kD cationic antimicrobial protein of human polymorphnuclear leukocytes: localization to a novel granule population. Blood 76, 825.
13. Savage, C.O.S., Lockwood, C.M., 1990. Antineutrophil antibodies in vasculits. Adv. Nephrol. 19, 225.
14. Schultz, H., Csernok, E., Schuster, A., Ernst, M., Gross, W.L., 1997. Important role of ANCA directed against bactericidal/permeability increasing protein in cystic fibrosis patients. Eur. Resp. J., submitted.
15. Stoffel, M.P., Csernok, E., Herzberg, C., Johnston, T., Carroll, S.F., Gross, W.L., 1996. Antineutrophil cytoplasmic antibodies (ANCA) directed against bactericidal/permeability increasing protein (BPI): a new seromarker for inflammatory bowel disease and associated disorders. Clin. Exp. Immunol. 104, 54.
16. Wiik, A., 1989. Detection of a standard procedure for indirect immunofluorescence detection of ANCA. APMIS 97, 12.
17. Wright, D.G., 1988. Human neutrophil degranulation. Methods Enzymol. 162, 538.
18. Zhao, M.H., Jones, S.J., Lockwood, C.M., 1995. Bactericidal/permeability increasing protein (BPI) is an important antigen for anti-neutrophil cytoplasmic autoantibodies (ANCA) in vasculitis. Clin. Exp. Immunol. 99, 49.
19. Zhao, M.H., Jayne, D.R.W., Ardiles, L.G., Culley, F., Hodson, M.E., Lockwood, C.M., 1996. Autoantibodies against bactericidal/permeability increasing protein in patients with cystic fibrosis. Q. J. Med. 89, 259.