HLA expression in a primary uveal melanoma, its cell line, and four of its metastases

British Journal of Ophthalmology

Volumn 81, Issue 11, 1997, Pages 989-993

  Blom, D J R ^a,b   Schurmans, L R H M ^a   De Waard Siebinga, I ^a   De Wolff Rouendaal, D ^a   Keunen, J E E ^a   Jager, M J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Department of Ophthalmology ^*  (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; HLA A2 ANTIGEN; HLA A3 ANTIGEN; HLA ANTIGEN; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; MONOCLONAL ANTIBODY;

AGED; ANTIGEN EXPRESSION; ARTICLE; CASE REPORT; CELL LINE; FEMALE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LIVER; MACROPHAGE; METASTASIS; NATURAL KILLER CELL; PRIORITY JOURNAL; SKIN; T LYMPHOCYTE; TISSUE SECTION; TUMOR CELL; UVEA MELANOMA;

EID: 0030786174     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.81.11.989     Document Type: Article

References (20)

1. Garrido F, Cabrera T, Concha A, Glew S, Ruiz-Cabello F, Stern PL. Natural history of HLA expression during tumour development. Immunol Today 1993;14:491-9.
2. Kaufman DS, Schoon RA, Robertson MJ, Leibson PJ. Inhibition of selective signaling events in natural killer cells recognizing major histocompatibility complex class I. Proc Natl Acad Sci 1995;92:6484-8.
3. Gumperz JE, Parham P. The enigma of the natural killer cell. Nature 1995;378:245-8.
4. Concha A, Esteban F, Cabrera T, Ruiz-Cabello F, Garrido F. Tumor aggresiveness and MHC class I and II antigens in laryngeal and breast cancer. Cancer Biol 1991;2:47-54.
5. Ferrone S, Marincola FM. Loss of HLA class I antigens by melanoma cells: molecular mechanisms, functional significance and clinical relevance. Immunol Today 1995;16:487-94.
6. Ruiter DJ, Mattijssen V, Bröcker EB, Ferrone S. MHC antigens in human melanomas. Semin Cancer Biol 1991;2:35-45.
7. Van Duinen SG, Ruiter DJ, Bröcker EB, Van Der Velde EA, Sorg C, Welvaart K, et al. Level of HLA antigens in locoregional metastases and clinical course of the disease in patients with melanoma. Cancer Res 1988;48:1019-25.
8. Jager MJ, De Wolff-Rouendaal D, Breebaart AC, Ruiter DJ. Expression of HLA antigens in paraffin sections of uveal melanomas. Doc Ophthalmol 1986;64:69-76.
9. Jager MJ, Van Der Pol JP, De Wolff-Rouendaal D, De Jong PTVM, Ruiter DJ. Decreased expression of HLA class II antigens on human uveal melanoma cells after in vivo X-ray irradiation. Am J Ophthalmol 1988;105:78-86.
10. Natali PG, Bigotti A, Nicotra MR, Nardi RM, Delovu A, Segatto O, et al. Analysis of the antigenic profile of uveal melanoma lesions with anti-cutaneous melanoma-associated antigen and anti-HLA monoclonal antobodies. Cancer Res 1989;49:1269-74.
11. De Waard-Siebinga I, Houbiers JGA, Hilders CGJM, De Wolff-Rouendaal D. Differential expression of HLA-A and -B alleles on uveal melanoma as determined by immunohistology. Ocul Immunol Inflamm 1996;4:1-14.
12. Tran JM, Murray TG, Uno T, Valore N, Ksander BR. Expression of HLA class I on ocular melanoma during progression from primary to metastatic disease. ARVO Abstracts. Invest Ophthalmol Vis Sci 1996;37:S208.
13. De Waard-Siebinga I, Blom DJR, Griffioen M, Schrier PI, Hoogendoorn E, Beverstock G, et al. Establishment and characterization of an uveal melanoma cell line. Int J Cancer 1995;62:155-61.
14. De Waard-Siebinga I, Kool J, Jager MJ. HLA antigen expression on uveal melanoma cells in vivo and in vitro. Hum Immunol 1995;44:111-7.
15. Lanier LL, Testi R, Bindl L, Phillips JH. Identity of Leu-19 (CD56) leucocyte differentiation antigen and neural cell adhesion molecule. J Exp Med 1989;169:2233-8.
16. De Waard-Siebinga I, Hilders CGJM, Hansen BE, Delft JL van, Jager MJ. HLA expression and tumor-infiltrating immune cells in uveal melanoma. Graefes Arch Clin Exp Ophthalmol 1995;234:34-42.
17. Blom DJR, Luyten GPM, Mooy CM, Kerkvliet S, Zwinderman AH, Jager MJ. HLA class I expression: a marker of poor prognosis in uveal melanoma. Invest Ophthalmol Vis Sci 1997;in press.
18. Whiteside TL, Herberman RB. The role of natural killer cells in immune surveillance of cancer. Curr Opin Immunol 1995;7:704-10.
19. Ma D, Luyten GP, Luider TM, Niederkorn JY. Relationship between natural killer cell susceptibility and metastasis of human uveal melanoma cells in a murine model. Invest Ophthalmol Vis Sci 1995;36:435-41.
20. Whelchel JC, Farah SE, McLean IW, Burnier MN. Immunohistochemistry of infiltrating lymphocytes in uveal malignant melanoma. Invest Ophthalmol Vis Sci 1993;34: 2603-6.