Flagella are a positive predictor for virulence in Legionella

Microbial Pathogenesis

Volumn 23, Issue 2, 1997, Pages 107-112

  Bosshardt, Stephen C ^a   Benson, Robert F ^b   Fields, Barry S ^b  

^a Binax Inc   (United States)

^b NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

Author keywords

Flagella; Hartmannella vermiformis; Legionella; Virulence

Indexed keywords

ARTICLE; BACTERIAL VIRULENCE; FLAGELLUM; LEGIONELLA PNEUMOPHILA; NONHUMAN; PRIORITY JOURNAL; SARCODINA;

BACTERIA (MICROORGANISMS); HARTMANNELLA VERMIFORMIS; LEGIONELLA; LEGIONELLA PNEUMOPHILA SEROGROUP 1; ORYCTOLAGUS CUNICULUS; SARCODINA;

EID: 0030785574     PISSN: 08824010     EISSN: None     Source Type: Journal    
DOI: 10.1006/mpat.1997.0134     Document Type: Article

References (22)

1. Chandler FW, Roth IL, Callaway CS, Bump JL, Thomason BM, Weaver RE. Flagella on Legionnaires disease bacteria. Ann Intern Med. 93:1980;711-714.
2. Rodgers FG, Greaves PW, Macrae AD, Lewis MJ. Electron microscopic evidence of flagella and pili onLegionella pneumophila. J Clin Pathol. 33:1980;1184-1188.
3. Elliott JA, Johnson W. Immunologic and biochemical relationships among flagella isolated fromLegionella pneumophila. Infect Immun. 33:1981;602-610.
4. Rowbotham TJ. Current views on the relationships between amoebae, legionellae and man. Isr J Med Sci. 22:1986;678-689.
5. Givskov M, Evel L, Christiansen G, Benedik MJ, Molin S. Induction of phospholipase - and flagellar synthesis inSerratia liquefaciensflhD. Mol. Microbiol. 15:1995;445-454.
6. Jacobs RF, Locksley RM, Wilson CB, Haas JE, Klebanoff SJ. Interaction of primate alveolar macrophages andLegionella pneumophila. J Clin Invest. 73:1984;1515-1523.
7. Pearlman EH, Jiwa H, Engleberg NC, Eisenstein B. Growth ofLegionella pneumophila. Microb Pathog. 5:1988;87-95.
8. McDade JE, Shepard CC. Virulent to avirulent conversion of Legionnaires disease bacterium (Legionella pneumophila. J Infect Dis. 139:1979;707-711.
9. Cianciotto NI, Fields BS. Legionella pneumophila mip. Proc Natl Acad Sci USA. 89:1992;5188-5191.
10. Fields BS, Utley-Fields SR, Chin Loy JN, White EH, Steffens WL, Shotts EB. Attachment and entry ofLegionella pneumophilaHartmannella vermiformis. J Infect Dis. 167:1993;1146-1150.
11. Elliott JA, Johnson W. Virulence conversion ofLegionella pneumophila. Infect Immun. 35:1982;943-946.
12. Pruckler JM, Benson RF, Moyenuddin M, Martin WT, Fields BS. Association of flagella expression and intracellular growth ofLegionella pneumophila. Infect Immun. 63:1995;4928-4932.
13. Macnab RM. Genetics and biogenesis of bacterial flagella. Ann Rev Genet. 26:1992;131-158.
14. Rodgers, FG, Laverick, T. 1984, Legionella pneumophilaLegionellaLegionella, 42, 4.
15. Bornstein N, Marmet D, Dumaine MH, Surgot M, Fleurette J. Detection of flagella in 278Legionella. J Clin Microbiol. 29:1991;953-956.
16. Heuner K, Bender-Beck L, Brand BC, Lück PC, Mann KH, Marre R, Ott M, Hacker J. Cloning and genetic characterization of the flagellum subunit gene (flaALegionella pneumophila. Infect Immun. 63:1995;2499-2507.
17. Ott M, Messner P, Heesemann J, Marre R, Hacker J. Temperature-dependent expression of flagella inLegionella. J Gen Microbiol. 137:1991;1955-1961.
18. Harshey RM, Toguchi A. Spinning tails: homologies among bacterial flagellar systems. Trends Microbiol. 4:1996;226-231.
19. King CH, Fields BS, Shotts EB Jr, White EH. Effects of cytochalasin D and methylamine on intracellular growth ofLegionella pneumophila. Infect Immun. 59:1991;758-763.
20. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedures and some applications. Proc Natl Acad Sci USA. 76:1979;4350-4354.
21. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
22. Fields BS, Nerad TA, Sawyer TK, King H, Barbaree JM, Martin WT, Morrill WE, Sanden GN. Characterization of an axenic strain ofHartmannella vermiformis. J Protozool. 37:1990;581-583.