Triplex-forming oligonucleotides can modulate aquaporin-5 gene expression in epithelial cells

Antisense and Nucleic Acid Drug Development

Volumn 7, Issue 5, 1997, Pages 523-529

  Delporte, Christine ^a   Panyutin, Igor G ^b   Sedelnikova, Olga A ^a   David Lillibridge, C ^a   O'Connell, Brian C ^a   Baum, Bruce J ^a,b  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AQUAPORIN; COMPLEMENTARY DNA; OLIGONUCLEOTIDE; POLYLYSINE;

ADENOVIRUS; ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELL STRAIN; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG DESIGN; DRUG TARGETING; EPITHELIUM CELL; GEL MOBILITY SHIFT ASSAY; GENE; GENE EXPRESSION; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; TRIPLE HELIX; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALIA;

EID: 0030784876     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1997.7.523     Document Type: Article

References (5)

1. AGRE, P., BROWN, D., and NIELSEN, S. (1995). Aquaporin water channels: Unanswered questions and unresolved controversies. Curr. Opinion Cell Biol. 7, 472-483.
2. ACRE, P., PRESTON, G.M., SMITH, B.L., JUNG, J.S., RAINA, S., MOON, C., GUGGINO, W.B., and NIELSEN, S. (1993). Aquaporin CHIP: The archetypal molecular water channel. Am. J. Physiol. 265, F463-F476.
3. BENNETT, C.F., CHIANG, M.-Y., CHAN, H., SHOEMAKER, J.E., and MIRABELLI, C.K. (1992). Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides. Mol. Pharmacol. 41, 1023-1033.
4. COONEY, M., CZERNUSZEWICZ, G., POSTEL, E.H., FLINT, S.J., and HOGAN, M.E. (1988). Site-specific oligonucleotide binding represses transcription of the human c-myc gene in vitro. Science 241, 456-459.
5. ZABNER, J., FASBENDER, A.J., MONIGER, T., POELLINGER, K.A., and WELSH, M.J. (1995). Cellular and molecular barriers to gene transfer by a cationic lipid. J. Biol. Chem. 270, 18997-19007.