메뉴 건너뛰기




Volumn 24, Issue 12, 1997, Pages 948-953

Rapid reversal of endothelial dysfunction in hypercholesterolaemic rabbits treated with simvastatin and pravastati n

Author keywords

Endothelium dysfunction; Endothelium dependent relaxation; Hypercholesterolaemia; Pravastatin; Rabbits; Simvastatin

Indexed keywords

CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MALONALDEHYDE; PRAVASTATIN; SIMVASTATIN;

EID: 0030784638     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1681.1997.tb02724.x     Document Type: Article
Times cited : (29)

References (37)
  • 1
    • 0000337070 scopus 로고
    • The Lipid Research Clinics Coronary Primary Prevention Trials results: I and II
    • Lipid Research Clinics Program. The Lipid Research Clinics Coronary Primary Prevention Trials results: I and II. JAMA 1970; 213: 1143-52.
    • (1970) JAMA , vol.213 , pp. 1143-1152
  • 2
    • 0025183769 scopus 로고
    • Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B
    • Brown G, Albers JJ, Fisher LD et al. Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B. N. Engl. J. Med. 1990; 323: 1289-98.
    • (1990) N. Engl. J. Med. , vol.323 , pp. 1289-1298
    • Brown, G.1    Albers, J.J.2    Fisher, L.D.3
  • 3
    • 0027285247 scopus 로고
    • Role of impaired endothelium-dependent vasodilation in ischemic manifestations of coronary artery disease
    • Meredith IT, Yeung AC, Weidinger FF et al. Role of impaired endothelium-dependent vasodilation in ischemic manifestations of coronary artery disease. Circulation 1993; 87 (suppl. V): V56-66.
    • (1993) Circulation , vol.87 , Issue.5 SUPPL.
    • Meredith, I.T.1    Yeung, A.C.2    Weidinger, F.F.3
  • 4
    • 0023928184 scopus 로고
    • Endothelium-derived relaxing factor: Identification as nitric oxide and role in the control of vascular tone and platelet function
    • Moncada S, Radomski MW, Palmer RM. Endothelium-derived relaxing factor: Identification as nitric oxide and role in the control of vascular tone and platelet function. Biochem. Pharmacol. 1988; 37: 2495-501.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 2495-2501
    • Moncada, S.1    Radomski, M.W.2    Palmer, R.M.3
  • 5
    • 0024553336 scopus 로고
    • Nitric oxide generating vasodilators and 8-bromocyclic GMP inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells
    • Garg UC, Hassid A. Nitric oxide generating vasodilators and 8-bromocyclic GMP inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J. Clin. Invest. 1990; 83: 1774-7.
    • (1990) J. Clin. Invest. , vol.83 , pp. 1774-1777
    • Garg, U.C.1    Hassid, A.2
  • 6
    • 0026059986 scopus 로고
    • Nitric oxide and prostacyclin: Divergence of inhibitory effects on monocyte chemotaxis and adhesion in vitro
    • Bath PMW, Hassel DG, Gladwin AM, Palmer RMJ, Martin JF. Nitric oxide and prostacyclin: Divergence of inhibitory effects on monocyte chemotaxis and adhesion in vitro. Arterioscler. Thromb. 1991; 11: 254-60.
    • (1991) Arterioscler. Thromb. , vol.11 , pp. 254-260
    • Bath, P.M.W.1    Hassel, D.G.2    Gladwin, A.M.3    Palmer, R.M.J.4    Martin, J.F.5
  • 7
    • 0028606058 scopus 로고
    • Effects of simvastatin and pravastatin on endothelium-dependent relaxation in hypercholesterolemic rabbits
    • Ribeiro Jorge PA, Osaki R, Metze K. Effects of simvastatin and pravastatin on endothelium-dependent relaxation in hypercholesterolemic rabbits. Exp. Toxicol. Pathol. 1994; 46: 465-9.
    • (1994) Exp. Toxicol. Pathol. , vol.46 , pp. 465-469
    • Ribeiro Jorge, P.A.1    Osaki, R.2    Metze, K.3
  • 9
    • 0027191073 scopus 로고
    • Beneficial effect of cholesterol-lowering therapy on coronary endothelium-dependent relaxation in hypercholesterolemic patients
    • Leung W-H, Lau C-P, Wong C-K. Beneficial effect of cholesterol-lowering therapy on coronary endothelium-dependent relaxation in hypercholesterolemic patients. Lancet 1993; 341: 1496-500.
    • (1993) Lancet , vol.341 , pp. 1496-1500
    • Leung, W.-H.1    Lau, C.-P.2    Wong, C.-K.3
  • 10
    • 0028283817 scopus 로고
    • Reduction in serum cholesterol with pravastatin improves endothelium-dependent coronary vasomotion in patients with hypercholesterolemia
    • Egashira K, Hirooka Y, Kai H et al. Reduction in serum cholesterol with pravastatin improves endothelium-dependent coronary vasomotion in patients with hypercholesterolemia. Circulation 1994; 89: 2519-24.
    • (1994) Circulation , vol.89 , pp. 2519-2524
    • Egashira, K.1    Hirooka, Y.2    Kai, H.3
  • 11
    • 0028910272 scopus 로고
    • Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease
    • Treasure CB, Klein L, Weintraub WS et al. Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease. N. Engl. J. Med. 1995; 332: 481-7.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 481-487
    • Treasure, C.B.1    Klein, L.2    Weintraub, W.S.3
  • 12
    • 0025989760 scopus 로고
    • Chronic treatment with polyethylene-glycolated superoxide dismutase partially restores endothelium-dependent vascular relaxations in cholesterol-fed rabbits
    • Mügge A, Elwell JH, Peterson TE, Hofmayer TG, Heistad DD, Harrison DG. Chronic treatment with polyethylene-glycolated superoxide dismutase partially restores endothelium-dependent vascular relaxations in cholesterol-fed rabbits. Circ. Res. 1991; 69: 1293-300.
    • (1991) Circ. Res. , vol.69 , pp. 1293-1300
    • Mügge, A.1    Elwell, J.H.2    Peterson, T.E.3    Hofmayer, T.G.4    Heistad, D.D.5    Harrison, D.G.6
  • 13
    • 0028177038 scopus 로고
    • Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits
    • Keaney JF, Gaziano JM, Xu-A et al. Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits. J. Clin. Invest. 1994; 93: 844-55.
    • (1994) J. Clin. Invest. , vol.93 , pp. 844-855
    • Keaney, J.F.1    Gaziano, J.M.2    Xu, A.3
  • 14
    • 0028326665 scopus 로고
    • Vitamin E protects against impairment of endothelium-mediated relaxations in cholesterol-fed rabbits
    • Stewart-Lee, Forster LA, Zadeh-Nourroz GAA, Angaard EE. Vitamin E protects against impairment of endothelium-mediated relaxations in cholesterol-fed rabbits. Arterioscler. Thromb. 1994; 14: 494-9.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 494-499
    • Stewart-Lee1    Forster, L.A.2    Zadeh-Nourroz, G.A.A.3    Angaard, E.E.4
  • 15
    • 0021196352 scopus 로고
    • Laboratory considerations: Determination of cholesterol, triglycerides, phospholipids and others lipids in blood and tissues
    • Naito HK, David JA. Laboratory considerations: Determination of cholesterol, triglycerides, phospholipids and others lipids in blood and tissues. Lab. Res. Methods Biol. Med. 1984; 10: 1-76.
    • (1984) Lab. Res. Methods Biol. Med. , vol.10 , pp. 1-76
    • Naito, H.K.1    David, J.A.2
  • 16
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissue
    • Folch JML, Stanley GHS. A simple method for the isolation and purification of total lipids from animal tissue. J. Biol. Chem. 1965; 226: 1780-6.
    • (1965) J. Biol. Chem. , vol.226 , pp. 1780-1786
    • Folch, J.M.L.1    Stanley, G.H.S.2
  • 17
    • 0022590124 scopus 로고
    • Lipid peroxidation and cellular damage in extrahepatic tissue of bromobenzene-intoxicated mice
    • Cassini AF, Ferrali M, Pompella A, Maellaro E, Comporti M. Lipid peroxidation and cellular damage in extrahepatic tissue of bromobenzene-intoxicated mice. Am. J. Pathol. 1986; 123: 520-31.
    • (1986) Am. J. Pathol. , vol.123 , pp. 520-531
    • Cassini, A.F.1    Ferrali, M.2    Pompella, A.3    Maellaro, E.4    Comporti, M.5
  • 19
    • 0026589006 scopus 로고
    • Atherosclerosis or lipoprotein-induced endothelial dysfunction
    • Flavahan NA. Atherosclerosis or lipoprotein-induced endothelial dysfunction. Circulation 1992; 85: 1927-38.
    • (1992) Circulation , vol.85 , pp. 1927-1938
    • Flavahan, N.A.1
  • 20
    • 0022006368 scopus 로고
    • Role of low density lipoprotein in the activation of plasma lysolecithin acyltransferase activity. Effect of chemical and enzymatic modifications of the lipoprotein on enzyme activity
    • Subbaiah PV, Chen CH, Bagdade JD, Albers JJ. Role of low density lipoprotein in the activation of plasma lysolecithin acyltransferase activity. Effect of chemical and enzymatic modifications of the lipoprotein on enzyme activity. Atherosclerosis 1985; 54: 99-110.
    • (1985) Atherosclerosis , vol.54 , pp. 99-110
    • Subbaiah, P.V.1    Chen, C.H.2    Bagdade, J.D.3    Albers, J.J.4
  • 21
    • 0027527297 scopus 로고
    • Effect of vitamin E on vascular integrity in cholesterol-fed guinea pig
    • Quiao Y, Yokoyama M, Kohji K, Asano G. Effect of vitamin E on vascular integrity in cholesterol-fed guinea pig. Arterioscler. Thromb. 1993; 13: 1885-92.
    • (1993) Arterioscler. Thromb. , vol.13 , pp. 1885-1892
    • Quiao, Y.1    Yokoyama, M.2    Kohji, K.3    Asano, G.4
  • 23
    • 0025023603 scopus 로고
    • Rapid and reversible inhibition by low density lipoprotein of the endothelium-dependent relaxation to hemostatic substances in porcine coronary arteries
    • Tomita T, Ezaki M, Nakamura K, Ionue Y. Rapid and reversible inhibition by low density lipoprotein of the endothelium-dependent relaxation to hemostatic substances in porcine coronary arteries. Circ. Res. 1990; 66: 18-27.
    • (1990) Circ. Res. , vol.66 , pp. 18-27
    • Tomita, T.1    Ezaki, M.2    Nakamura, K.3    Ionue, Y.4
  • 24
    • 0026689102 scopus 로고
    • Hypolipidemic drugs reduce lipoprotein susceptibility to undergo lipid peroxidation: In vitro and ex vivo studies
    • Hoffman R, Brook GJ, Aviram MM. Hypolipidemic drugs reduce lipoprotein susceptibility to undergo lipid peroxidation: in vitro and ex vivo studies. Atherosclerosis 1992; 93: 105-13.
    • (1992) Atherosclerosis , vol.93 , pp. 105-113
    • Hoffman, R.1    Brook, G.J.2    Aviram, M.M.3
  • 25
    • 0027492038 scopus 로고
    • Sinvastatin inhibits the oxidation of low density lipoprotein by activated human monocytes-derived macrophages
    • Giroux LM, Davigni J, Naruszewicz M. Sinvastatin inhibits the oxidation of low density lipoprotein by activated human monocytes-derived macrophages. Biochem. Biophys. Acta 1993; 1165: 335-8.
    • (1993) Biochem. Biophys. Acta , vol.1165 , pp. 335-338
    • Giroux, L.M.1    Davigni, J.2    Naruszewicz, M.3
  • 26
    • 0028019136 scopus 로고
    • Pravastatin effectively lowers LDL cholesterol in familial combined hyperlipidemia without changing LDL subclass pattern
    • Franceschini G, Cassinotti M, Vecchio G et al. Pravastatin effectively lowers LDL cholesterol in familial combined hyperlipidemia without changing LDL subclass pattern. Arterioscler. Thromb. 1994; 14: 1569-75.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 1569-1575
    • Franceschini, G.1    Cassinotti, M.2    Vecchio, G.3
  • 27
    • 0028887870 scopus 로고
    • Molecular physiology of reverse cholesterol transport
    • Fielding CJ, Fielding PE. Molecular physiology of reverse cholesterol transport. J. Lipid Res. 1995; 36: 211-28.
    • (1995) J. Lipid Res. , vol.36 , pp. 211-228
    • Fielding, C.J.1    Fielding, P.E.2
  • 28
    • 0026658579 scopus 로고
    • Apolipoproteins, membrane cholesterol domains and the regulation of cholesterol efflux
    • Rothblat GH, Mahlberg FH, Johnson WJ, Phillips MC. Apolipoproteins, membrane cholesterol domains and the regulation of cholesterol efflux. J. Lipid Res. 1992; 33: 1091-7.
    • (1992) J. Lipid Res. , vol.33 , pp. 1091-1097
    • Rothblat, G.H.1    Mahlberg, F.H.2    Johnson, W.J.3    Phillips, M.C.4
  • 29
    • 0025633049 scopus 로고
    • Cholesterol trafficking in cells
    • Oram JF. Cholesterol trafficking in cells. Curr. Opin. Lipidol. 1990; 1: 416-21.
    • (1990) Curr. Opin. Lipidol. , vol.1 , pp. 416-421
    • Oram, J.F.1
  • 31
    • 0029737574 scopus 로고
    • Non-lipid-related effects of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors
    • Corsini A, Bernini F, Quarato P et al. Non-lipid-related effects of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. Cardiology 1966; 87: 458-68.
    • (1966) Cardiology , vol.87 , pp. 458-468
    • Corsini, A.1    Bernini, F.2    Quarato, P.3
  • 32
    • 0029098006 scopus 로고
    • The Kuopio Atherosclerosis Prevention Study (KAPS): Effect of pravastatin treatment on lipids, oxidation resistance of lipoproteins, and atherosclerotic progression
    • Solenen R, Nyssonen K, Porkkala-Sarataho E, Solenen JT. The Kuopio Atherosclerosis Prevention Study (KAPS): Effect of pravastatin treatment on lipids, oxidation resistance of lipoproteins, and atherosclerotic progression. Am. J. Cardiol. 1995; 76: C34-9.
    • (1995) Am. J. Cardiol. , vol.76
    • Solenen, R.1    Nyssonen, K.2    Porkkala-Sarataho, E.3    Solenen, J.T.4
  • 34
    • 0024461808 scopus 로고
    • Tissue selective acute effects of inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase on cholesterol biosynthesis in lens
    • Mosley St, Kalinoswki SS, Schafer BL, Tanaka RD. Tissue selective acute effects of inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase on cholesterol biosynthesis in lens. J. Lipid Res. 1989; 30: 1411-20.
    • (1989) J. Lipid Res. , vol.30 , pp. 1411-1420
    • Mosley, St.1    Kalinoswki, S.S.2    Schafer, B.L.3    Tanaka, R.D.4
  • 35
    • 0026814425 scopus 로고
    • Comparative pharmacokinetics of lovastatin, simvastatin and pravastatin in humans
    • Pentikainen PJ, Saraheimo M, Schartz JI et al. Comparative pharmacokinetics of lovastatin, simvastatin and pravastatin in humans. J. Clin. Pharmacol. 1992; 32: 136-40.
    • (1992) J. Clin. Pharmacol. , vol.32 , pp. 136-140
    • Pentikainen, P.J.1    Saraheimo, M.2    Schartz, J.I.3
  • 37
    • 0024972452 scopus 로고
    • Animal safely and toxicology of sivastatin and related hydroxy-methylglutaryl-coenzyme A reductase inhibitors
    • Gerson RJ, Macdonald JS, Alberts AW et al. Animal safely and toxicology of sivastatin and related hydroxy-methylglutaryl-coenzyme A reductase inhibitors. Am. J. Med. 1988; 87: 4A-28S-38.
    • (1988) Am. J. Med. , vol.87
    • Gerson, R.J.1    Macdonald, J.S.2    Alberts, A.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.