2'-O-methylthiomethyl modifications in hammerhead ribozymes

Nucleosides and Nucleotides

Volumn 16, Issue 7-9, 1997, Pages 955-958

  Karpeisky, Alexander ^a   Gonzalez, Carolyn ^a   Burgin, Alex B ^a   Usman, Nassim ^a   Beigelman, Leonid ^a  

^a Sirna Therapeutics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEASE; PHOSPHORAMIDIC ACID DERIVATIVE; RIBOZYME;

CONFERENCE PAPER; DRUG STABILITY; DRUG SYNTHESIS; RNA CLEAVAGE; SERUM;

EID: 0030784503     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/07328319708006114     Document Type: Conference Paper

References (10)

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2. Beigelman, L.; Mcswiggen, J. A.; Draper, K. G.; Gonzalez, C.; Jensen, K.; Karpeisky, A. M.; Modak, A. S.; Matulic-Adamic, J.; Direnzo, A. B.; Haeberli, P.; Sweedler, D.; Tracz, D.; Grimm, S.; Wincott, F. E.; Thackray, V. G.; Usman, N. J Biol Chem 1995, 270, 25702-25708.
3. Beigelman, L.; Karpeisky, A.; Matulicadamic, J.; Haeberli, P.; Sweedler, D.; Usman, N. Nucleic Acids Res 1995, 23, 4434-4442.
4. Corey, E. J.; Bock, M. J. Tetrahedron Lett 1975, , 3269.
5. Pojer, P. M.; Angual, S. Austr J Chem 1978, 31, 1031-1040.
6. Zavgorodny, S.; Polianski, M.; Besidsky, E.; Kriukov, V.; Sanin, A.; Pokrovskaya, M.; Gurskaya, G.; Lonnberg, H.; Azhayev, A. Tetrahedron Lett 1991, 32, 7593-7596.
7. Medina, J. S.; Salomon, M.; Kyler, K. S. Tetrahedron Lett. 1988, 29, 3773-3776.
8. Veeneman, G. H.; van der Marel, G. A.; van den Elst, H.; van Boom, J. H. Rec Trav Chim 1990, 109, 449-451.
9. Wincott, F. E.; DiRenzo, A.; Shaffer, C.; Grimm, S.; Tracz, D.; Workman, C.; Sweedler, D.; Gonzalez, C.; Scaringe, S.; Usman, N. Nucleic Acids Res. 1995, 23, 2677-2684.
10. Scaringe, S. A.; Franklyn, C.; Usman, N. Nucleic Acid Res 1990, 18, 5433.