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Volumn 45, Issue 3-4, 1997, Pages 190-192

Redirected cellular cytotoxicity employing bispecific antibodies and other multifunctional binding proteins

Author keywords

Bispecific antibody; Cytotoxicity; HER2 neu CD16; Staphylococcal enterotoxin A

Indexed keywords

BISPECIFIC ANTIBODY; HYBRID PROTEIN; MONOCLONAL ANTIBODY; NACOLOMAB TAFENATOX; STAPHYLOCOCCUS ENTEROTOXIN A; SUPERANTIGEN; UNCLASSIFIED DRUG;

EID: 0030783183     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002620050430     Document Type: Article
Times cited : (11)

References (10)
  • 1
    • 4243638318 scopus 로고    scopus 로고
    • Overview of clinical trials employing antibody-targeted superantigens
    • in press
    • Alpaugh RK, Weiner LM (1997) Overview of clinical trials employing antibody-targeted superantigens. Adv Drug Rev (in press)
    • (1997) Adv Drug Rev
    • Alpaugh, R.K.1    Weiner, L.M.2
  • 3
    • 0028863319 scopus 로고
    • Antibody-targeted superantigens are potent inducers of tumor-infiltrating T lymphocytes in vivo
    • Dohlsten M, Hansson J, Ohlsson L et al. (1995) Antibody-targeted superantigens are potent inducers of tumor-infiltrating T lymphocytes in vivo. Proc Natl Acad Sci USA 92:9791
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9791
    • Dohlsten, M.1    Hansson, J.2    Ohlsson, L.3
  • 4
    • 0025245397 scopus 로고
    • Potentiation of tumor lysis by a bispecific antibody that binds to CA19-9 antigen and Fcγ receptor expressed by human large granular lymphocytes
    • Garcia de Palazzo IE, Gercel-Taylor C, Kitson J, Weiner LM (1990) Potentiation of tumor lysis by a bispecific antibody that binds to CA19-9 antigen and Fcγ receptor expressed by human large granular lymphocytes. Cancer Res 50:7123.
    • (1990) Cancer Res , vol.50 , pp. 7123
    • Garcia De Palazzo, I.E.1    Gercel-Taylor, C.2    Kitson, J.3    Weiner, L.M.4
  • 7
    • 0027388920 scopus 로고
    • A human tumor xenograft model of therapy with a bispecific monoclonal antibody targeting c-erbB-2 and CD16
    • Weiner LM, Holmes M, Adams GP, LaCreta F, Watts P, Garcia de Palazzo IG (1993) A human tumor xenograft model of therapy with a bispecific monoclonal antibody targeting c-erbB-2 and CD16. Cancer Res 53:94
    • (1993) Cancer Res , vol.53 , pp. 94
    • Weiner, L.M.1    Holmes, M.2    Adams, G.P.3    LaCreta, F.4    Watts, P.5    Garcia De Palazzo, I.G.6
  • 9
    • 0028883695 scopus 로고
    • Clinical development of 2B1, a bispecific murine monoclonal antibody targeting c-erbB-2 and FcγRIII
    • Weiner LM, Clark JI, Ring DB, Alpaugh RK (1995) Clinical development of 2B1, a bispecific murine monoclonal antibody targeting c-erbB-2 and FcγRIII. J Hematother 4:453
    • (1995) J Hematother , vol.4 , pp. 453
    • Weiner, L.M.1    Clark, J.I.2    Ring, D.B.3    Alpaugh, R.K.4
  • 10
    • 4243680181 scopus 로고    scopus 로고
    • Superantigen-targeted therapy: Phase I escalating repeat dose trial of PNU-214565, a fusion protein composed of staphylococcal enterotoxin A (SEA) and C242 antibody Fab fragment in patients with advanced gastrointestinal malignancies
    • Weiner LM, McAleer C, Schultz J, Persson B, Persson R, Dohlsten M, Vitek L, Giantonio BJ, Nielsen SE, Alpaugh RK (1997) Superantigen-targeted therapy: phase I escalating repeat dose trial of PNU-214565, A fusion protein composed of staphylococcal enterotoxin A (SEA) and C242 antibody Fab fragment in patients with advanced gastrointestinal malignancies. Proc Am Soc Clin Oncol 16:436a
    • (1997) Proc Am Soc Clin Oncol , vol.16
    • Weiner, L.M.1    McAleer, C.2    Schultz, J.3    Persson, B.4    Persson, R.5    Dohlsten, M.6    Vitek, L.7    Giantonio, B.J.8    Nielsen, S.E.9    Alpaugh, R.K.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.