The fetoplacental pressor effects of low-dose acetylsalicylic acid and angiotensin II in the ex vivo cotyledon model

American Journal of Obstetrics and Gynecology

Volumn 177, Issue 5, 1997, Pages 1093-1096

  Napolitano, P G ^a   Hoeldtke, N J ^a   Moore, K H ^a   Calhoun, B C ^a   Christensen, E D ^a   Markenson, G R ^a   Hume R F , Jr ^a  

^a DAVID GRANT MEDICAL CENTER   (United States)

Author keywords

Acetylsalicylic acid; Angiotensin II; Aspirin; Placental perfusion

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOTENSIN; PROSTACYCLIN; THROMBOXANE A2;

BLOOD VESSEL REACTIVITY; CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; FETOPLACENTAL UNIT; HUMAN; HUMAN TISSUE; HYPERTENSION; PERFUSION PRESSURE; PREECLAMPSIA; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; VASOSPASM;

EID: 0030782501     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9378(97)70021-8     Document Type: Conference Paper

References (20)

1. DJ Fitzgerald G Mayo F Catella SS Entman GA. Fitzgerald Increased thromboxane synthesis in normal pregnancy is mainly derived from platelets Am J Obstet Gynecol 157 1987 325 330
2. 2 production but normal prostacyclin by the placenta in hypertensive pregnancies Prostaglandins 27 1984 87 95
3. SW. Walsh Preeclampsia: an imbalance in placental prostacyclin and thromboxane production Am J Obstet Gynecol 152 1985 335 340
4. M Hamberg J Svensson B. Samuelsson Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides Proc Natl Acad Sci U S A 72 1975 2994 2998
5. 2 Nature 315 1985 511 513
6. SW Walsh MJ Behr NH. Allen Placental prostacyclin production in normal and toxemic pregnancies Am J Obstet Gynecol 151 1985 10 15
7. S Bunting R Gryglewski S Moncada JR. Vane Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac arteries and inhibits platelet aggregation Prostaglandins 12 1976 897 913
8. S Maigaard A Forman K-E. Andersson Differential effects of angiotensin, vasopressin and oxytocin on various smooth muscle tissues within the human uteroplacental unit Acta Physiol Scand 128 1986 23 31
9. TN. Tulenko The actions of prostaglandins and cyclo-oxygenase inhibition on the resistance vessels supplying the human fetal placenta Prostaglandins 21 1981 1033 1043
10. NF Gant GL Daley S Chand PJ Whalley PC. MacDonald A study of angiotensin II pressor response throughout pregnancy J Clin Invest 52 1973 2682 2689
11. T Oney H. Kaulhaousen The value of the angiotensin sensitivity test in the early diagnosis of hypertensive disorders in pregnancy Am J Obstet Gynecol 142 1982 17 20
12. RB Everett RJ Worley PC MacDonald NF. Gant Effect of prostaglandin synthetase inhibitors on pressor response to angiotensin II in human pregnancy J Clin Endocrinol Metab 46 1978 1007 1010
13. L Sanchez-Ramos MJ O'Sullivan J. Garrido-Calderon Effect of low-dose aspirin on angiotensin II pressor response in human pregnancy Am J Obstet Gynecol 156 1987 193 194
14. B Spitz RR Magness SM Cox CE Brown CR Rosenfeld NF. Gant I: Effects on angiotensin II pressor responses and blood prostaglandin concentrations in pregnant women sensitive to angiotensin II Am J Obstet Gynecol 159 1988 1035 1043
15. CE Brown NF Cant K Cox B Spitz CR Rosenfeld RR. Magness Low-dose aspirin, II: relationship of angiotensin II pressor responses, circulating eicosanoids, and pregnancy outcomes Am J Obstet Gynecol 163 1990 1853 1861
16. RL Jacobson A Brewer A Eis TA Siddiqi L. Myatt Transfer of aspirin across the perfused human placental cotyledon Am J Obstet Gynecol 165 1991 939 944
17. DG Glance MG EIder DL Bloxam L. Myatt The effects of the components of the renin-angiotensin system on the isolated perfused human placental cotyledon Am J Obstet Gynecol 149 1984 450 454
18. GR Markenson K Foley AS Maslow JN. Kopelman The effect of atrial natriuretic factor and angiotensin II on fetal-placental perfusion in the ex vivo cotyledon model Am J Obstet Gynecol 173 1995 1143 1147
19. DG Glance MG Elder L. Myatt The actions of prostaglandins and their interactions with angiotensin II in the isolated perfused human placental cotyledon Br J Obstet Gynaecol 93 1986 488 494
20. JA Thorp SW Walsh PC. Brath Low-dose aspirin inhibits thromboxane, but not prostacyclin, production by human placental arteries Am J Obstet Gynecol 159 1988 1381 1384