Multidrug resistance-related proteins in primary choroidal melanomas and in vitro cell lines

Investigative Ophthalmology and Visual Science

Volumn 38, Issue 12, 1997, Pages 2523-2530

  Van Der Pol, Jeroen P ^a   Blom, Derk J R ^b   Flens, Marcel J ^c   Luyten, Gre P M ^d   De Waard Siebinga, Itte ^b   Koornneef, Leo ^a   Scheper, Rik J ^c   Jager, Martine J ^b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^d ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Cell lines; Immunohistochemistry; Melanoma; Multidrug resistance; Uvea

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCEIN; GLYCOPROTEIN P; MONOCLONAL ANTIBODY; RHODAMINE 123; VALSPODAR;

ARTICLE; CELL CULTURE; CHOROID MELANOMA; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOTHERAPY; METASTASIS; MULTIDRUG RESISTANCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; UVEA MELANOMA;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; CHOROID NEOPLASMS; DRUG RESISTANCE, MULTIPLE; FLOW CYTOMETRY; FLUORESCEINS; FLUORESCENT DYES; HUMANS; IMMUNOENZYME TECHNIQUES; MELANOMA; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; P-GLYCOPROTEIN; RHODAMINE 123; RHODAMINES; TUMOR CELLS, CULTURED; VAULT RIBONUCLEOPROTEIN PARTICLES;

EID: 0030782442     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Seddon JM, Albert DM, Lavin PT, Robinson N. A prognostic factor study of disease-free interval and survival following enucleation of disseminated uveal melanoma. Arch Ophthalmol. 1983;101:1894-1899.
2. Kath R, Hayungs J, Bornfeld N, Sauerwein W, Hoffken K, Seeber S. Prognosis and treatment of disseminated uveal melanoma. Cancer. 1993;72(7):2219-2223.
3. De Vita VT Jr. Principles of chemotherapy. In: De Vita VT, Hellman S, Rosenberg SA, eds. Principles and Practice of Oncology. Philadelphia: JB Lippincott; 1989:276-300.
4. Gottesman MM. How cancer cells evade chemotherapy. Cancer Res. 1993;53:747-754.
5. Kartner N, Evernden-Porelle D, Bradley G, Ling V. Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies. Nature. 1985;316:820
6. Ueda K, Cornwell MM, Gottesman MM, et al. The mdrl gene, responsible for multidrug resistance, codes for P-glycoprotein. Biochem Biophys Res Comm. 1986;141:956.
7. Willingham MC, Richert ND, Cornwell MM, et al. Immunocytochemical localization of P170 at the plasma membrane of multidrug-resistant human cells. J Histochem Cytochem. 1987;35:1451.
8. Gottesman MM, Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Ann Rev Biochem. 1993;62:385-427.
9. Cordon-Cardo C, O'Brien JP, Boccia J, Casals D, Bertino JR, Melamed MR. Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues. J Histol Cytol. 1990;38:1277.
10. Rischin D, Ling V. Multidrug resistance in leukemia. In: Freireich EJ, Kantarnan H, eds. Leukemia: Advances, Research and Treatment. Amsterdam: Kluwer Academic Publishers; 1993:269-293.
11. Georges E, Sharom FJ, Ling V. Multidrug resistance and chemosensitization: Therapeutic implications for cancer chemotherapy. Adv Pharmacol. 1990;21:185-220.
12. Ford JM, Hait WN. Pharmacology of drugs that alter multidrug resistance in cancer. Pharmacol Rev. 1990;42:155-199.
13. Dalton WS, Grogan TM, Meltzer PS, et al. Drug resistance in multiple myeloma and non-Hodgkin's lymphoma: Detection of P-glycoprotein and potential circumvention by addition of verapamil to chemotherapy. J Clin Oncol. 1989; 7:415-424.
14. Sonneveld P, Durie BGM, Lokhorst HM, et al. Modulation of multidrug-resistant multiple myeloma by cyclosporin. Lancet. 1992;340:255-259.
15. Slovack ML, Pelkey HJ, Bhardwaj G, Kurz EU, Deeley RG, Cole SPS. Localization of a novel multidrug resistance-associated gene in the HT1080/DR4 and H69AR human tumor cell lines. Cancer Res. 1993; 53:3221-3225.
16. Zaman GLR, Versantvoort CHM, Smit JJM, et al. Analysis of the expression of MRP, the gene for a new putative transmembrane drug transporter, in human multidrug-resistant lung cancer cell lines. Cancer Res. 1993;53:1747-1750.
17. Grant CE, Valdimarsson G, Hipfner DR, Almquist KC, Cole SPC, Deeley RG. Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs. Cancer Res. 1994; 54:357-361.
18. Childs S, Ling V. The MDR superfamily of genes and its biological implications. In DeVita VT, Hellman S, Rosenberg SA, eds. Important Advances in Oncology. Philadelphia: JB Lippincott; 1994:21-36.
19. Zaman GLR, Flens MJ, van Leusden MR, et al. The human multidrug resistance-associated protein (MRP) is a plasma membrane drug efflux pump. Proc Natl Acad Sci USA. 1994;91:8822-8826.
20. Scheper RJ, Broxterman HJ, Scheffer GL, et al. Over-expression of a 110-kD vesicular protein in non-P-glycoprotein-mediated multidrug resistance. Cancer Res. 1993;53:1475-1479.
21. Scheffer GL, Wijngaard PLJ, Flens MJ, et al. The drug resistance-related protein LRP is a major vault protein. Nature Med. 1995;1:578-582.
22. Scheper RJ, Scheffer GL, Flens MJ, et al. Role of LRP-major vault protein in multidrug resistance. In: Gupta S, Tsuruo T, eds. Multidrug Resistance in Cancer Cells: Cellular, Biochemical, Molecular and Biological Aspects. New York: John Wiley & Sons; 1996:109-119.
23. List A, Spier CS, Grogan TM, et al. Overexpression of the major vault transporter protein LRP predicts treatment outcome in AML. Blood. 1995;87:2464-2469.
24. Izquierdo MA, van der Zee AGJ, Vermorken JB, et al. Drug resistance-associated marker LRP for prediction of response to chemotherapy and prognoses in advanced ovarian carcinoma. J Natl Cancer Inst. 1995;87:1230-1237.
25. Georges E, Bradley G, Gariepy J, Ling V. Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies. Proc Natl Acad Sci USA. 1990;87:152-156.
26. Scheper RJ, Bulte JWM, Brakkee JGM, et al. Monoclonal antibody JSB-1 detects a highly conserved epitope on the P-glycoprotein associated with multidrug resistance. Int J Cancer. 1988;42:389-394.
27. Flens MJ, Izquierdo MA, Scheffer GL, et al. Immunochemical detection of MRP in human multidrug-resistant tumor cells by monoclonal antibodies. Cancer Res. 1994;4:4557-4563.
28. Waard-Siebinga I de, Blom DJR, Griffioen M, et al. Establishment and characterization of an uveal melanoma cell line. Int J Cancer. 1995;62:155-162.
29. Luyten GPM, Naus NC, Mooy CM, et al. Establishment and characterization of primary and metastatic uveal melanoma cell lines. Int J Cancer. 1996;66:1-8.
30. Kan-Mitchell J, Mitchell MS, Rao N, Liggett PE. Characterization of uveal melanoma cell lines that grow as xenografts in rabbit eyes. Invest Ophthalmol Vis Sci. 1989;30:829-834.
31. Ksander BR, Rubsamen PE, Olsen KR, Cousins SW, Streilein JW. Studies of tumor-infiltrating lymphocytes from a human choroidal melanoma. Invest Ophthalmol Vis Sci. 1991;32:3198-3208.
32. Hamada H, Tsuruo T. Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells revealed by monoclonal antibodies. Proc Natl Acad Sci USA. 1986;83:7758-7789.
33. Zijlstra JG, de Vries EGE, Mulder NH. Multifactorial drug resistance in an adriamycin-resistant human small cell lung carcinoma cell line. Cancer Res. 1987;47:1780-1784.
34. Shen DW, Fojo A, Chin JE, et al. Human multidrug-resistant cell lines: Increased mdrl expression can precede gene amplification. Science. 1986;232:643-645.
35. Arceci RJ, Stieglitz K, Bras J, Schinkel A, Baas F, Croop J. Monoclonal antibody to an external epitope of the human mdrl P-glycoprotein. Cancer Res. 1993;53:310-317.
36. Feller N, Kuiper CM, Lankelma J, et al. Functional detection of MDR1/P170 and MRP/P190-mediated multidrug resistance in tumor cells by flow cytometry. Br J Cancer. 1995;72:543-549.
37. McNamara M, Clyne M, Dunne B, et al. Multidrug resistance in ocular melanoma. Br J Ophthalmol. 1996; 80:1009-1012.
38. Broxterman HJ, Lankelma J, Pinedo HM. How to probe clinical tumor samples for P-glycoprotein and multidrug resistance protein. Eur J Cancer. 1996; 32A:1024-1033.
39. Schadendorf D, Makki A, Stahr C, et al. Membrane transport proteins associated with drug resistance expressed in human melanoma. Am J Pathol. 1995; 147:1545-1552.